Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia (Q33456516)

26 July 2017

title

Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia (English)

1 reference

26 July 2017

1 reference

1 reference

Xinchun Jin

1 reference

26 July 2017

Jie Liu

1 reference

26 July 2017

Ke J Liu

1 reference

26 July 2017

Gary A Rosenberg

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26 July 2017

Yi Yang

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26 July 2017

Wenlan Liu

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26 July 2017

language of work or name

English

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publication date

26 November 2012

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26 July 2017

published in

Experimental Neurology

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26 July 2017

volume

240

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26 July 2017

page(s)

9-16

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Delivering minocycline into brain endothelial cells with liposome-based technology

26 July 2017

cites work

1 reference

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21 June 2018

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Normobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke

21 June 2018

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Minocycline development for acute ischemic stroke

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Oxygen therapy improves energy metabolism in focal cerebral ischemia

21 June 2018

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MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemia

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Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke

21 June 2018

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Targeting the ischemic penumbra

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Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding study

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Inhibition of gp91(phox) contributes towards normobaric hyperoxia afforded neuroprotection in focal cerebral ischemia

21 June 2018

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Oxygen therapy reduces secondary hemorrhage after thrombolysis in thromboembolic cerebral ischemia

21 June 2018

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Increased nuclear apoptosis-inducing factor after transient focal ischemia: a 12/15-lipoxygenase-dependent organelle damage pathway.

21 June 2018

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Increased intranuclear matrix metalloproteinase activity in neurons interferes with oxidative DNA repair in focal cerebral ischemia.

21 June 2018

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Normobaric hyperoxia reduces the neurovascular complications associated with delayed tissue plasminogen activator treatment in a rat model of focal cerebral ischemia

21 June 2018

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Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

21 June 2018

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21 June 2018

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Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke

21 June 2018

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Synergistic effect of an endothelin type A receptor antagonist, S-0139, with rtPA on the neuroprotection after embolic stroke

21 June 2018

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21 June 2018

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Minocycline treatment in acute stroke: an open-label, evaluator-blinded study.

21 June 2018

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Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia

21 June 2018

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Effect of synthetic matrix metalloproteinase inhibitors on lipopolysaccharide-induced blood-brain barrier opening in rodents: Differences in response based on strains and solvents

21 June 2018

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Reperfusion injury following cerebral ischemia: pathophysiology, MR imaging, and potential therapies

21 June 2018

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Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke

21 June 2018

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Venturi mask adjuvant oxygen therapy in severe acute ischemic stroke.

21 June 2018

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21 June 2018

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Matrix metalloproteinases in early diabetic retinopathy and their role in alteration of the blood-retinal barrier

21 June 2018

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Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

21 June 2018

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Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy

21 June 2018

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21 June 2018

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Mitochondrially localized active caspase-9 and caspase-3 result mostly from translocation from the cytosol and partly from caspase-mediated activation in the organelle. Lack of evidence for Apaf-1-mediated procaspase-9 activation in the mitochondria

21 June 2018

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Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia

21 June 2018

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21 June 2018

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Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation

21 June 2018

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Delayed minocycline but not delayed mild hypothermia protects against embolic stroke

21 June 2018

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A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

21 June 2018

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Pathobiology of ischaemic stroke: an integrated view

21 June 2018

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Ischemic penumbra: the therapeutic window

21 June 2018

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Reperfusion Injury: Demonstration of Brain Damage Produced by Reperfusion after Transient Focal Ischemia in Rats

21 June 2018

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Expression of interleukin-1 beta converting enzyme gene family and bcl-2 gene family in the rat brain following permanent occlusion of the middle cerebral artery

21 June 2018

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Increased blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia: role of lipid peroxidation and calpain-1/2, matrix metalloproteinase-2/9, and RhoA overactivation.

21 June 2018

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Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Delayed treatment with minocycline ameliorates neurologic impairment through activated microglia expressing a high-mobility group box1-inhibiting mechanism

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Minocycline and hypothermia for reperfusion injury after focal cerebral ischemia in the rat: effects on BBB breakdown and MMP expression in the acute and subacute phase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Normobaric hyperoxia delays perfusion/diffusion mismatch evolution, reduces infarct volume, and differentially affects neuronal cell death pathways after suture middle cerebral artery occlusion in rats

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Delayed minocycline treatment reduces long-term functional deficits and histological injury in a rodent model of focal ischemia.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Electron paramagnetic resonance-guided normobaric hyperoxia treatment protects the brain by maintaining penumbral oxygenation in a rat model of transient focal cerebral ischemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Apoptotic cell death progression after photothrombotic focal cerebral ischaemia: effects of the lipophilic iron chelator 2,2'-dipyridyl.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

A pilot study of normobaric oxygen therapy in acute ischemic stroke

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Minocycline protects against permanent cerebral ischemia in wild type but not in matrix metalloprotease-9-deficient mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Induction of caspase-mediated cell death by matrix metalloproteinases in cerebral endothelial cells after hypoxia-reoxygenation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: influence of astrocyte contact

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563388

Normobaric hyperoxia - a promising approach to expand the time window for acute stroke treatment

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23195595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tight junctions contain oligomeric protein assembly critical for maintaining blood-brain barrier integrity in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23195595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interstitial pO2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23195595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EXPNEUROL.2012.11.018

1 reference

26 July 2017

1 reference

26 July 2017

1 reference