Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze? (Q33392127)

26 July 2017

8 references

25 April 2019

20 June 2019

19 September 2019

22 October 2019

4 November 2019

19 December 2019

20 December 2019

3 December 2020

Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze? (English)

1 reference

biomedical investigative technique

26 July 2017

4 references

25 April 2019

20 June 2019

19 September 2019

22 October 2019

1 reference

19 September 2019

1 reference

22 October 2019

1 reference

4 November 2019

1 reference

19 December 2019

Parkinson disease associated proteins

1 reference

20 December 2019

1 reference

1 reference

3 December 2020

Vladimir L Buchman

1 reference

26 July 2017

Natalia Ninkina

series ordinal

1 reference

26 July 2017

publication date

1 December 2008

9 references

26 July 2017

25 April 2019

20 June 2019

19 September 2019

22 October 2019

4 November 2019

19 December 2019

20 December 2019

3 December 2020

Neurotoxicity Research

9 references

26 July 2017

25 April 2019

20 June 2019

19 September 2019

22 October 2019

4 November 2019

19 December 2019

20 December 2019

3 December 2020

1 reference

26 July 2017

1 reference

26 July 2017

page(s)

329-341

1 reference

Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression

26 July 2017

cites work

1 reference

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Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation

21 June 2018

2 references

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21 June 2018

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Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis

31 October 2018

1 reference

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The aggregation and fibrillation of alpha-synuclein

21 June 2018

1 reference

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Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein

21 June 2018

1 reference

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Influence of different promoters on the expression pattern of mutated human alpha-synuclein in transgenic mice.

21 June 2018

1 reference

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Effects of the cholesterol-lowering compound methyl-beta-cyclodextrin in models of alpha-synucleinopathy

21 June 2018

1 reference

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Mice lacking alpha-synuclein are resistant to mitochondrial toxins

21 June 2018

1 reference

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Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.

21 June 2018

1 reference

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Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

21 June 2018

1 reference

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Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein

21 June 2018

1 reference

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Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy

21 June 2018

1 reference

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Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

21 June 2018

1 reference

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Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

21 June 2018

1 reference

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Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice

21 June 2018

1 reference

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Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

21 June 2018

1 reference

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Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons

21 June 2018

1 reference

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Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications

21 June 2018

1 reference

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alpha-Synuclein locus triplication causes Parkinson's disease

21 June 2018

1 reference

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Clinical overview of the synucleinopathies

21 June 2018

1 reference

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Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease.

21 June 2018

1 reference

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 June 2018

1 reference

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The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease

21 June 2018

1 reference

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Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice

21 June 2018

1 reference

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Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

21 June 2018

1 reference

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Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

21 June 2018

1 reference

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Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

21 June 2018

1 reference

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Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

21 June 2018

1 reference

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Amino acid determinants of alpha-synuclein aggregation: putting together pieces of the puzzle

21 June 2018

1 reference

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Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

21 June 2018

1 reference

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Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes

21 June 2018

1 reference

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Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

21 June 2018

1 reference

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beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

21 June 2018

1 reference

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Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

21 June 2018

1 reference

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beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

21 June 2018

1 reference

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alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

21 June 2018

1 reference

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The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.

21 June 2018

1 reference

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Synucleinopathies: clinical and pathological implications

21 June 2018

1 reference

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Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

21 June 2018

1 reference

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A Drosophila model of Parkinson's disease

21 June 2018

1 reference

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

21 June 2018

1 reference

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 June 2018

1 reference

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α-Synuclein in Lewy bodies

21 June 2018

1 reference

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 June 2018

1 reference

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Identification of two distinct synucleins from human brain

21 June 2018

1 reference

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Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

21 June 2018

1 reference

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The rat brain synucleins; family of proteins transiently associated with neuronal membrane

21 June 2018

1 reference

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A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.

21 June 2018

1 reference

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Transgenic mice overexpressing tyrosine-to-cysteine mutant human alpha-synuclein: a progressive neurodegenerative model of diffuse Lewy body disease

31 October 2018

1 reference

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Rasagiline is neuroprotective in a transgenic model of multiple system atrophy

31 October 2018

1 reference

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Accumulation of phosphorylated alpha-synuclein in dopaminergic neurons of transgenic mice that express human alpha-synuclein

31 October 2018

1 reference

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High dose levodopa therapy is not toxic in multiple system atrophy: experimental evidence

31 October 2018

1 reference

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Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

31 October 2018

1 reference

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Selective loss of nigral dopamine neurons induced by overexpression of truncated human alpha-synuclein in mice

31 October 2018

1 reference

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Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice

31 October 2018

1 reference

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Proteasome dysfunction in aged human alpha-synuclein transgenic mice

31 October 2018

1 reference

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Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

31 October 2018

1 reference

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Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

31 October 2018

1 reference

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Familial Parkinson mutant alpha-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans

31 October 2018

1 reference

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Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human alpha-synuclein in mice

31 October 2018

1 reference

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Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

31 October 2018

1 reference

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Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

31 October 2018

1 reference

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Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease

31 October 2018

1 reference

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Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

31 October 2018

1 reference

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An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Lipid rafts mediate the synaptic localization of alpha-synuclein.

31 October 2018

1 reference

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Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

31 October 2018

1 reference

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Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice

31 October 2018

1 reference

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Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Lewy body diseases and multiple system atrophy as alpha-synucleinopathies

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153657

Human Wild-Type α-Synuclein Impairs Neurogenesis

31 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF03033857

The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease

21 January 2018

1 reference

12 December 2020

Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

1 reference

12 December 2020

Microglial activation mediates neurodegeneration related to oligodendroglial α-synucleinopathy: Implications for multiple system atrophy

1 reference

12 December 2020

Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration

1 reference

12 December 2020

Neuropathology in mice expressing human alpha-synuclein

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03033857

1 reference

Dimensions Publication ID

26 July 2017

1043900333

0 references

Fatcat ID

release_zbbkf3kk6ffyfnezctp4rwwjnm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zbbkf3kk6ffyfnezctp4rwwjnm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3153657

1 reference

26 July 2017

1 reference