Chk1 Kinase Negatively Regulates Mitotic Function of Cdc25A Phosphatase through 14-3-3 Binding (Q33292076)

25 July 2017

title

Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding (English)

1 reference

25 July 2017

Chk1 Kinase Negatively Regulates Mitotic Function of Cdc25A Phosphatase through 14-3-3 Binding (English)

1 reference

https://api.crossref.org/works/10.1128/MCB.23.21.7488-7497.2003

21 March 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.23.21.7488-7497.2003

21 March 2024

Mei-Shya Chen

1 reference

25 July 2017

Helen Piwnica-Worms

series ordinal

1 reference

25 July 2017

Christine E. Ryan

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14559997

21 March 2024

language of work or name

English

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publication date

1 November 2003

1 reference

full work available at URL

25 July 2017

https://europepmc.org/articles/pmc207598?pdf=render

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14559997

https://europepmc.org/articles/PMC207598

21 March 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14559997

https://europepmc.org/articles/PMC207598?pdf=render

21 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14559997

https://doi.org/10.1128/mcb.23.21.7488-7497.2003

21 March 2024

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14559997

https://journals.asm.org/doi/pdf/10.1128/MCB.23.21.7488-7497.2003

21 March 2024

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https://api.crossref.org/works/10.1128/MCB.23.21.7488-7497.2003

https://www.tandfonline.com/doi/pdf/10.1128/MCB.23.21.7488-7497.2003

21 March 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.23.21.7488-7497.2003

Molecular and Cellular Biology

21 March 2024

published in

1 reference

25 July 2017

1 reference

25 July 2017

1 reference

25 July 2017

page(s)

7488-7497

1 reference

Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint

25 July 2017

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21 June 2018

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Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

21 June 2018

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21 June 2018

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Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

21 June 2018

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21 June 2018

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21 June 2018

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The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 June 2018

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Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

21 June 2018

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Positive regulation of Wee1 by Chk1 and 14-3-3 proteins

21 June 2018

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21 June 2018

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Role of the Cdc25A phosphatase in human breast cancer

21 June 2018

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Rapid destruction of human Cdc25A in response to DNA damage

21 June 2018

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The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 June 2018

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Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle

21 June 2018

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14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

21 June 2018

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DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding

21 June 2018

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21 June 2018

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CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 June 2018

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Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases

21 June 2018

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Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site

21 June 2018

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Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25.

21 June 2018

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Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import

21 June 2018

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A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

21 June 2018

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14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

21 June 2018

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Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase

21 June 2018

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Cdc25A is a novel phosphatase functioning early in the cell cycle

21 June 2018

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21 June 2018

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CDC25 phosphatases as potential human oncogenes

21 June 2018

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14-3-3 proteins associate with cdc25 phosphatases

21 June 2018

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Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

21 June 2018

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Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner

21 June 2018

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Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

21 June 2018

1 reference

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 June 2018

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14-3-3 binding regulates catalytic activity of human Wee1 kinase

21 June 2018

1 reference

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The C-terminal tail of the dual-specificity Cdc25B phosphatase mediates modular substrate recognition

31 October 2018

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Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=207598

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=207598

Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=207598

Identification of a C-terminal cdc25 sequence required for promotion of germinal vesicle breakdown

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=207598

A maternal form of the phosphatase Cdc25A regulates early embryonic cell cycles in Xenopus laevis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=207598

Mechanisms of p34cdc2 regulation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=207598

Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=207598

Overexpression of CDC25A and CDC25B in head and neck cancers

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14559997

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

cdc25a and the splicing variant cdc25b2, but not cdc25B1, -B3 or -C, are over-expressed in aggressive human non-Hodgkin's lymphomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14559997

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of CDC25B phosphatases subcellular localization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14559997

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

2366

Gasparotto D.

1997

1 reference

https://api.crossref.org/works/10.1128/MCB.23.21.7488-7497.2003

21 March 2024

Identifiers

1 reference

25 July 2017

1 reference

25 July 2017

1 reference