Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition (Q40793182)

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20 October 2019

title

Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition (English)

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16 May 2024

I. Hoffmann

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G. Draetta

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E. Karsenti

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English

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publication date

1 September 1994

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15 September 1994

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National Center for Biotechnology Information

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full work available at URL

16 May 2024

https://europepmc.org/articles/pmc395357?pdf=render

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open access

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16 May 2024

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16 May 2024

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fj.1460-2075.1994.tb06750.x

16 May 2024

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10.1002/J.1460-2075.1994.TB06750.X

Crossref

DOI

https://api.crossref.org/works/10.1002/J.1460-2075.1994.TB06750.X

http://onlinelibrary.wiley.com/wol1/doi/10.1002/j.1460-2075.1994.tb06750.x/fullpdf

16 May 2024

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10.1002/J.1460-2075.1994.TB06750.X

Crossref

DOI

https://api.crossref.org/works/10.1002/J.1460-2075.1994.TB06750.X

16 May 2024

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20 October 2019

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4302-4310

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Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15

20 October 2019

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Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts

24 September 2017

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Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

24 September 2017

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Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis

24 September 2017

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Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts.

24 September 2017

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Cyclins and cyclin-dependent kinases: take your partners

24 September 2017

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

24 September 2017

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p21 is a universal inhibitor of cyclin kinases

24 September 2017

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

24 September 2017

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Cdc25A is a novel phosphatase functioning early in the cell cycle

24 September 2017

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Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior phosphorylation of cdc25C by p34cdc2 on sites phosphorylated at mitosis

24 September 2017

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Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase

24 September 2017

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

24 September 2017

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Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

24 September 2017

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Automatic microinjection system facilitates detection of growth inhibitory mRNA

24 September 2017

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Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2

24 September 2017

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Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication

24 September 2017

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p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

24 September 2017

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Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites

24 September 2017

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Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

24 September 2017

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Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

24 September 2017

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Cell Cycle Regulation in the Yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe

24 September 2017

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Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation

24 September 2017

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mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2.

24 September 2017

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An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells.

24 September 2017

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Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates

24 September 2017

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Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

24 September 2017

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A family of human cdc2-related protein kinases

24 September 2017

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Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

24 September 2017

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Role of phosphorylation in p34cdc2 activation: identification of an activating kinase

24 September 2017

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Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

24 September 2017

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24 September 2017

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Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner

24 September 2017

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Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

24 September 2017

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Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity

24 September 2017

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Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase

24 September 2017

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p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15

24 September 2017

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cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2

24 September 2017

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p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast

24 September 2017

1 reference

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Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

25 September 2017

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Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis

17 June 2018

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cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

17 June 2018

1 reference

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Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase

17 June 2018

1 reference

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The cdc25 protein contains an intrinsic phosphatase activity

17 June 2018

1 reference

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Regulation of the cdc25 protein during the cell cycle in Xenopus extracts

17 June 2018

1 reference

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A mouse cdc25 homolog is differentially and developmentally expressed

17 June 2018

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

17 June 2018

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Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

19 August 2018

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12 December 2020

Performance of an automated system for capillary microinjection into living cells

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12 December 2020

Dephosphorylation and activation of Xenopusp34 cdc2 protein kinase during the cell cycle

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12 December 2020

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

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12 December 2020

Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex

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12 December 2020

Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement

1 reference

12 December 2020

10.1002/J.1460-2075.1994.TB06750.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7523110%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7523110%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7523110%20AND%20SRC:MED&resulttype=core&format=json