Biochemical mechanisms of the RNA-induced silencing complex (Q33274614)

25 July 2017

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title

Biochemical mechanisms of the RNA-induced silencing complex (English)

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25 July 2017

Zain Paroo

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25 July 2017

Qinghua Liu

series ordinal

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25 July 2017

Xiaodong Wang

series ordinal

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25 July 2017

language of work or name

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1 March 2007

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25 July 2017

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25 July 2017

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25 July 2017

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25 July 2017

page(s)

187-194

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Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

25 July 2017

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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A species of small antisense RNA in posttranscriptional gene silencing in plants

21 January 2018

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Targeted mRNA degradation by double-stranded RNA in vitro

21 January 2018

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 January 2018

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RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

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MicroRNAs: small RNAs with a big role in gene regulation

21 January 2018

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Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

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R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

21 January 2018

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

21 January 2018

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

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Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

21 January 2018

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A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

21 January 2018

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Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

21 January 2018

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Single processing center models for human Dicer and bacterial RNase III

21 January 2018

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Argonaute2, a link between genetic and biochemical analyses of RNAi

21 January 2018

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Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity

21 January 2018

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The rde-1 gene, RNA interference, and transposon silencing in C. elegans

21 January 2018

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AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals

21 January 2018

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Slicer function of Drosophila Argonautes and its involvement in RISC formation

21 January 2018

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Crystal structure of Argonaute and its implications for RISC slicer activity

21 January 2018

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Purified Argonaute2 and an siRNA form recombinant human RISC

21 January 2018

1 reference

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Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

21 January 2018

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Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes

21 January 2018

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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

21 January 2018

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Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

21 January 2018

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

21 January 2018

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The role of PACT in the RNA silencing pathway

21 January 2018

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RISC assembly defects in the Drosophila RNAi mutant armitage.

21 January 2018

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ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Mechanisms of gene silencing by double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Identification of novel argonaute-associated proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

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A protein sensor for siRNA asymmetry

21 January 2018

1 reference

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Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila

21 January 2018

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

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Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

21 January 2018

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

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Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

21 January 2018

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A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

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Short RNAs repress translation after initiation in mammalian cells.

21 January 2018

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Kinetic analysis of the RNAi enzyme complex

21 January 2018

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Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells

21 January 2018

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MicroRNA-directed cleavage of HOXB8 mRNA

21 January 2018

1 reference

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Inhibition of translational initiation by Let-7 MicroRNA in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Relief of microRNA-mediated translational repression in human cells subjected to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

A role for the P-body component GW182 in microRNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

A distinct small RNA pathway silences selfish genetic elements in the germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

Characterization of the piRNA Complex from Rat Testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

A novel class of small RNAs bind to MILI protein in mouse testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

inferred from DOI database lookup

7 January 2021

based on heuristic

A germline-specific class of small RNAs binds mammalian Piwi proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7310148

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CR.7310148

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Dimensions Publication ID

25 July 2017

1017764357

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