Kinetic analysis of the RNAi enzyme complex (Q38340658)

2 September 2017

title

Kinetic analysis of the RNAi enzyme complex (English)

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2 September 2017

Phillip D Zamore

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Benjamin Haley

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2 September 2017

publication date

30 May 2004

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Nature Structural & Molecular Biology

2 September 2017

published in

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2 September 2017

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2 September 2017

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2 September 2017

page(s)

599-606

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

2 September 2017

cites work

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RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

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ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Tolerance for mutations and chemical modifications in a siRNA.

21 January 2018

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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

21 January 2018

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21 January 2018

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A biochemical framework for RNA silencing in plants

21 January 2018

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Small interfering RNA molecules as potential anti-human rhinovirus agents: in vitro potency, specificity, and mechanism

21 January 2018

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Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis

21 January 2018

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Expression profiling reveals off-target gene regulation by RNAi

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MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

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Computational identification of microRNA targets.

21 January 2018

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Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

21 January 2018

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Specificity of microRNA target selection in translational repression

21 January 2018

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siRNA function in RNAi: a chemical modification analysis

21 January 2018

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A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

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Sequence-specific inhibition of small RNA function

21 January 2018

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Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

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Prediction of mammalian microRNA targets

21 January 2018

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Prediction of plant microRNA targets

21 January 2018

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Identification of Drosophila MicroRNA targets

21 January 2018

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RNAi in human cells: basic structural and functional features of small interfering RNA.

21 January 2018

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Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids

21 January 2018

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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

21 January 2018

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RISC assembly defects in the Drosophila RNAi mutant armitage.

21 January 2018

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Rational siRNA design for RNA interference

21 January 2018

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RISC is a 5' phosphomonoester-producing RNA endonuclease

21 January 2018

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A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

21 January 2018

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MicroRNA targets in Drosophila

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

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bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

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The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs.

21 January 2018

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The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

21 January 2018

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The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

21 January 2018

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A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

21 January 2018

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In vitro analysis of RNA interference in Drosophila melanogaster.

21 January 2018

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The RNA-induced silencing complex is a Mg2+-dependent endonuclease.

21 January 2018

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Investigating the structure of human RNase H1 by site-directed mutagenesis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NSMB780

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2 September 2017

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