Cholinergic neuronal defect without cell loss in Huntington's disease (Q33258207)

24 July 2017

title

Cholinergic neuronal defect without cell loss in Huntington's disease (English)

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24 July 2017

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Lesley Colgan

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Raymund A C Roos

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24 July 2017

Richard L M Faull

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24 July 2017

Patrik Brundin

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24 July 2017

Jia-Yi Li

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Ruben Smith

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24 July 2017

Hinfan Chung

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24 July 2017

Sara Rundquist

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24 July 2017

Marion L C Maat-Schieman

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24 July 2017

Elisabet Englund

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24 July 2017

Yong-Jian Liu

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24 July 2017

publication date

20 September 2006

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24 July 2017

published in

Human Molecular Genetics

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24 July 2017

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24 July 2017

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24 July 2017

page(s)

3119-3131

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

24 July 2017

cites work

1 reference

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

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21 January 2018

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Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: implications for ischemia and Huntington's disease

21 January 2018

1 reference

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Sparing of cholinergic neurons following quinolinic acid lesions of the rat striatum

21 January 2018

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Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease

21 January 2018

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Regional distribution of choline acetyltransferase in the human brain: changes in Huntington's chorea

21 January 2018

1 reference

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Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia

21 January 2018

1 reference

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Brain muscarinic cholinergic receptors in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL252

Neurochemical alterations in Huntington's chorea: a study of post-mortem brain tissue

21 January 2018

1 reference

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Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers

21 January 2018

1 reference

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Choline therapy in Huntington chorea

21 January 2018

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Physostigmine in choreiform movement disorders

21 January 2018

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Donepezil for Huntington's disease

21 January 2018

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Effects of rivastigmine on motor and cognitive impairment in Huntington's disease

21 January 2018

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Rivastigmine in the treatment of Huntington's disease

21 January 2018

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A combination drug therapy improves cognition and reverses gene expression changes in a mouse model of Huntington's disease.

21 January 2018

1 reference

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The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies

21 January 2018

1 reference

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Regulation of the cholinergic gene locus by the repressor element-1 silencing transcription factor/neuron restrictive silencer factor (REST/NRSF)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL252

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

21 January 2018

1 reference

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

21 January 2018

1 reference

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Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation

21 January 2018

1 reference

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Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease

21 January 2018

1 reference

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

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Transcriptional abnormalities in Huntington disease

21 January 2018

1 reference

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Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

21 January 2018

1 reference

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In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets

21 January 2018

1 reference

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Plastic and behavioral abnormalities in experimental Huntington's disease: a crucial role for cholinergic interneurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL252

Evidence for specific cognitive deficits in preclinical Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL252

Behavioral changes after acetylcholinesterase inhibition with physostigmine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL252

Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL252

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

21 January 2018

1 reference

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Developments of a water-maze procedure for studying spatial learning in the rat

21 January 2018

1 reference

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A new and rapid colorimetric determination of acetylcholinesterase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL252

21 January 2018

Identifiers

DOI

10.1093/HMG/DDL252

1 reference

release_fhfht6uljrgybapm2ae6koli6a

24 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fhfht6uljrgybapm2ae6koli6a

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference