Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease (Q34763178)

4 August 2017

title

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease (English)

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4 August 2017

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4 August 2017

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4 August 2017

Xianbo Zhou

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Emma Hockly

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4 August 2017

Victoria M Richon

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4 August 2017

Benjamin Woodman

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4 August 2017

Donna L Smith

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4 August 2017

Eddie Rosa

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4 August 2017

Kirupa Sathasivam

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4 August 2017

Shabnam Ghazi-Noori

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4 August 2017

Amarbirpal Mahal

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4 August 2017

Philip A S Lowden

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4 August 2017

Joan S Steffan

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4 August 2017

J Lawrence Marsh

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4 August 2017

Leslie M Thompson

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4 August 2017

Paul A Marks

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4 August 2017

language of work or name

English

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publication date

7 February 2003

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

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inferred from page(s)

published in

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4 August 2017

volume

100

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4 August 2017

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4 August 2017

page(s)

2041-2046

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Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

4 August 2017

cites work

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Histone deacetylases and cancer: causes and therapies

7 July 2018

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Interaction of Huntington disease protein with transcriptional activator Sp1

7 July 2018

1 reference

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Histone deacetylase inhibitors reduce polyglutamine toxicity

7 July 2018

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Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients

7 July 2018

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Altered transcription in yeast expressing expanded polyglutamine

7 July 2018

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

7 July 2018

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Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

7 July 2018

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

7 July 2018

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Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

7 July 2018

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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

7 July 2018

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Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

7 July 2018

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

7 July 2018

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Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

7 July 2018

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Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

7 July 2018

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

7 July 2018

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

7 July 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

7 July 2018

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More powerful procedures for multiple significance testing

7 July 2018

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Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

7 July 2018

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Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

26 October 2018

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Environmental enrichment slows disease progression in R6/2 Huntington's disease mice

26 October 2018

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Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine

26 October 2018

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Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles

26 October 2018

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Inhibitors of histone deacetylase are potentially effective anticancer agents

26 October 2018

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Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

26 October 2018

1 reference

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Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.

26 October 2018

1 reference

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Chemoprevention of carcinogen-induced mammary tumorigenesis by the hybrid polar cytodifferentiation agent, suberanilohydroxamic acid (SAHA)

26 October 2018

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Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

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12 December 2020

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

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12 December 2020

The T-lineage-affiliated CD2 gene lies within an open chromatin environment in acute promyelocytic leukemia cells

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12 December 2020

Cyclodextrin Drug Carrier Systems

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0437870100

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4 August 2017

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4 August 2017

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