Apoptosis: biochemical aspects and clinical implications (Q33185094)

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7 January 2021

The biology of apoptosis

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Apoptosis: a guide for the perplexed.

7 January 2021

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The case against apoptosis

7 January 2021

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Apoptosis and necrosis in cerebrovascular disease

7 January 2021

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Apoptosis in relevant clinical situations: contribution of apoptosis in myocardial infarction

7 January 2021

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"Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation: analysis by immunogold electron microscopy combined with In situ nick end-labeling

7 January 2021

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Apoptotic versus autophagic cell death in heart failure

7 January 2021

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

7 January 2021

1 reference

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Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

7 January 2021

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7 January 2021

Apoptosis in development

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Pathways of apoptosis in lymphocyte development, homeostasis, and disease

7 January 2021

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On the origin, evolution, and nature of programmed cell death: a timeline of four billion years

7 January 2021

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Apoptosis in the nervous system

7 January 2021

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Survival factors regulating ovarian apoptosis -- dependence on follicle differentiation.

7 January 2021

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Mutations in apoptosis genes: a pathogenetic factor for human disease

7 January 2021

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Investigation of suspected deficient Fas-mediated apoptosis in a father and son

7 January 2021

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2001 Warkany lecture: to die or not to die, the role of apoptosis in normal and abnormal mammalian development

7 January 2021

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7 January 2021

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The machinery of programmed cell death.

7 January 2021

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7 January 2021

Mechanisms of apoptosis

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Predominant identification of RNA-binding proteins in Fas-induced apoptosis by proteome analysis

7 January 2021

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Microarray analysis of eosinophils reveals a number of candidate survival and apoptosis genes

7 January 2021

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The frequency of U-shaped dose responses in the toxicological literature

7 January 2021

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Apoptosis: biphasic dose responses.

7 January 2021

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Defying death after DNA damage.

7 January 2021

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p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

7 January 2021

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ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

7 January 2021

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

7 January 2021

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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

7 January 2021

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Apoptotic pathways: paper wraps stone blunts scissors

7 January 2021

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Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells

7 January 2021

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The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

7 January 2021

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Apaf1 in developmental apoptosis and cancer: how many ways to die?

7 January 2021

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

7 January 2021

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The biochemistry of apoptosis

7 January 2021

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Bax and Bak independently promote cytochrome C release from mitochondria

7 January 2021

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The dynamic process of apoptosis analyzed by flow cytometry using Annexin-V/propidium iodide and a modified in situ end labeling technique

7 January 2021

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Detection of localized caspase activity in early apoptotic cells by laser scanning cytometry

7 January 2021

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Phosphatidylserine, a death knell

7 January 2021

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Identification of a factor that links apoptotic cells to phagocytes

7 January 2021

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

7 January 2021

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Detection of apoptosis in tissue sections.

7 January 2021

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Morphological and biochemical characterization and analysis of apoptosis

7 January 2021

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Texture analysis of fluorescence lifetime images of AT- and GC-rich regions in nuclei.

7 January 2021

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A flow cytometric method using Hoechst 33342 and propidium iodide for simultaneous cell cycle analysis and apoptosis determination in unfixed cells

7 January 2021

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Sensitive analysis of apoptosis using confocal laser scan microscopy

7 January 2021

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Images in clinical medicine. Apoptosis in myelodysplastic syndromes

7 January 2021

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Detection of apoptotic cells in human colorectal cancer by two different in situ methods: antibody against single-stranded DNA and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling (TUNEL) methods.

7 January 2021

1 reference

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Improved detection of apoptotic cells using a modified in situ TUNEL technique

7 January 2021

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Measurement of apoptosis by the TUNEL method using scintillating microplates.

7 January 2021

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Silver-stained comet assay for detection of apoptosis

7 January 2021

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Comet assay and early apoptosis

7 January 2021

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Contribution of apoptosis to responses in the comet assay

7 January 2021

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A simple method for accurate estimation of apoptotic cells

7 January 2021

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Capillary electrophoresis of DNA damage after irradiation: apoptosis and necrosis

7 January 2021

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Flow cytometry in analysis of cell cycle and apoptosis

7 January 2021

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Analysis of apoptosis by laser scanning cytometry

7 January 2021

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Serum-soluble fas level determines clinical symptoms and outcome of patients with aggressive non-Hodgkin's lymphoma

7 January 2021

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Apoptosis in the skeletal muscle of patients with heart failure: investigation of clinical and biochemical changes.

7 January 2021

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Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 cells.

7 January 2021

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Phosphatidylserine induces apoptosis in CHO cells without mitochondrial dysfunction in a manner dependent on caspases other than caspases-1, -3, -8 and -9.

7 January 2021

1 reference

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Hoechst 33342 induces apoptosis and alters tata box binding protein/DNA complexes in nuclei from BC3H-1 myocytes

7 January 2021

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Disruption of replication protein A/single-stranded DNA complexes during apoptosis in HL-60 cells

7 January 2021

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Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342

7 January 2021

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Synthetic DNA minor groove-binding drugs

7 January 2021

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Replication Protein A (RPA): The Eukaryotic SSB

7 January 2021

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Functional analysis of the four DNA binding domains of replication protein A. The role of RPA2 in ssDNA binding

7 January 2021

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Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A

7 January 2021

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RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

7 January 2021

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Gal4-VP16 and Gal4-AH increase the orientational and axial specificity of TATA box recognition by TATA box binding protein

7 January 2021

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Identification of novel E2F1-regulated genes by microarray

7 January 2021

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E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

7 January 2021

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The transcription factor E2F1 modulates apoptosis of neurons

7 January 2021

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A structural model for the ternary cleavable complex formed between human topoisomerase I, DNA, and camptothecin

7 January 2021

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Clinical applications of the camptothecins.

7 January 2021

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How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair?

7 January 2021

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Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

7 January 2021

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Nitric oxide. Biochemistry, pathophysiology, and detection

7 January 2021

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Nitric oxide synthases: structure, function and inhibition

7 January 2021

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Regulation of endothelial nitric oxide synthase: location, location, location

7 January 2021

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Relationship of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and early-onset coronary artery disease

7 January 2021

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Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy

7 January 2021

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Endothelial nitric oxide synthase gene polymorphism in women with idiopathic recurrent miscarriage

7 January 2021

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Nitric oxide in immunity and inflammation

7 January 2021

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Altered immune responses in mice lacking inducible nitric oxide synthase

7 January 2021

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Oxidation of nitric oxide by oxygen in biological systems monitored by porphyrinic sensor

7 January 2021

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Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors.

7 January 2021

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Simulation of the diffusion and reaction of endogenously produced nitric oxide

7 January 2021

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Kinetics of nitric oxide binding to R-state hemoglobin

7 January 2021

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Nitric oxide can inhibit apoptosis or switch it into necrosis

7 January 2021

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Nitric oxide (NO): an effector of apoptosis

7 January 2021

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The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta

7 January 2021

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Nitric Oxide-Mediated Apoptosis in Murine Mastocytoma

7 January 2021

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Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta

7 January 2021

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Genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells exposed to peroxynitrite generated from SIN-1.

7 January 2021

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Rapid attenuation of AP-1 transcriptional factors associated with nitric oxide (NO)-mediated neuronal cell death

7 January 2021

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Dissociation of DNA fragmentation from other hallmarks of apoptosis in nitric oxide-treated neutrophils: differences between individual nitric oxide donor drugs

7 January 2021

1 reference

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Expression of Nitric-Oxide Synthase (NOS) in Injured CNS Neurons as Shown by NADPH Diaphorase Histochemistry

7 January 2021

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Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor

7 January 2021

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Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation.

7 January 2021

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Nitric oxide in excitable tissues: physiological roles and disease

7 January 2021

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Redox signaling: nitrosylation and related target interactions of nitric oxide

7 January 2021

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Impairment of brain mitochondrial function by reactive nitrogen species: the role of glutathione in dictating susceptibility

7 January 2021

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Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells

7 January 2021

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Requirement for cGMP in Nerve Cell Death Caused by Glutathione Depletion

7 January 2021

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Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression

7 January 2021

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5-s-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons

7 January 2021

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Bcl-2 protects macrophages from nitric oxide-induced apoptosis

7 January 2021

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Transcription factors p53 and HIF-1alpha as targets of nitric oxide

7 January 2021

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Regulation of gene expression by nitric oxide

7 January 2021

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Nitric oxide and the regulation of gene expression

7 January 2021

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Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-kappaB binding to DNA.

7 January 2021

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Alteration of NF-κB p50 DNA Binding Kinetics by S-Nitrosylation

7 January 2021

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Nitric oxide (NO) disrupts specific DNA binding of the transcription factor c-Myb in vitro

7 January 2021

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Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

7 January 2021

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Nitric Oxide Inhibits Fas-induced Apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation

7 January 2021

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Stretch-induced programmed myocyte cell death

7 January 2021

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Nitric Oxide Inhibits Apoptosis by Preventing Increases in Caspase-3-like Activity via Two Distinct Mechanisms

7 January 2021

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Nitric oxide-mediated inhibition of follicular apoptosis is associated with HSP70 induction and Bax suppression

7 January 2021

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Potential cardioprotective actions of no-releasing aspirin

7 January 2021

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‘Centennial’ Nobel Conference on apoptosis and human disease

7 January 2021

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Inducible gene expression in apoptosis

7 January 2021

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Signal Transduction and the Control of Gene Expression

7 January 2021

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

7 January 2021

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Regulation of E2F: a family of transcription factors involved in proliferation control

7 January 2021

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Transcription-factor mutations and disease

7 January 2021

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Functional interactions and signaling properties of mammalian DNA mismatch repair proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Identification of hTAF(II)80 delta links apoptotic signaling pathways to transcription factor TFIID function

7 January 2021

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Transcription activator protein 1 (AP-1) mediates NO-induced apoptosis of adult cardiomyocytes

7 January 2021

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c-Jun mediates axotomy-induced dopamine neuron death in vivo

7 January 2021

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The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor

7 January 2021

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CCAAT/enhancer-binding protein beta plays a regulatory role in differentiation and apoptosis of neuroblastoma cells

7 January 2021

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Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1

7 January 2021

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Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

7 January 2021

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Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Nuclear factor-kappaB to the rescue of cytokine-induced neuronal survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

AP-1 in cell proliferation and survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

p53 is required for radiation-induced apoptosis in mouse thymocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Thymocyte apoptosis induced by p53-dependent and independent pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Activation of caspases in p53-induced transactivation-independent apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Induction of apoptosis in HeLa cells by trans-activation-deficient p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Tumor surveillance via the ARF-p53 pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Role of p73 in malignancy: tumor suppressor or oncogene?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Death signals changes in TFIID.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

The NF-kappa B and I kappa B proteins: new discoveries and insights

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Missing pieces in the NF-kappaB puzzle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

IκB kinase: Beginning, not the end

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Neurotrophins: roles in neuronal development and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Activation of nuclear factor kappaB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

STATs: signal transducers and activators of transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

The role of STATs in transcriptional control and their impact on cellular function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

From bench to clinic with apoptosis-based therapeutic agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Drug delivery to mitochondria: the key to mitochondrial medicine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Cellular stress response and apoptosis in cancer therapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Therapeutic applications of apoptosis research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Caspase inhibitors for liver disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Endogenous endothelium-derived nitric oxide inhibits myocardial caspase activity: implications for treatment of end-stage heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Controlling apoptosis by inhibition of caspases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Adenovirus-mediated E2F-1 gene transfer efficiently induces apoptosis in melanoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

E2F-1 is essential for normal epidermal wound repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Death and anti-death: tumour resistance to apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Cellular mechanisms for the repression of apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

Protein thiol modification and apoptotic cell death as cGMP-independent nitric oxide (NO) signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8

inferred from DOI database lookup

7 January 2021

based on heuristic

DNA damage and nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0009-8981%2802%2900297-8