A "no-hybrids" screen for functional antagonizers of human p53 transactivator function: dominant negativity in fission yeast. (Q31015221)

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12 November 2019

title

A "no-hybrids" screen for functional antagonizers of human p53 transactivator function: dominant negativity in fission yeast (English)

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12 November 2019

author

Tassula Proikas-Cezanne

series ordinal

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12 November 2019

Waddell S

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12 November 2019

Jenkins JR

series ordinal

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12 November 2019

language of work or name

English

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publication date

1 September 2001

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12 November 2019

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12 November 2019

volume

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12 November 2019

issue

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12 November 2019

page(s)

6001-6008

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Regulation of p53 stability

12 November 2019

cites work

1 reference

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Suppression of human colorectal carcinoma cell growth by wild-type p53

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Human p53 inhibits growth in Schizosaccharomyces pombe

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Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

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Drosophila p53 binds a damage response element at the reaper locus

21 January 2018

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Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay

21 January 2018

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p53 functions as a cell cycle control protein in osteosarcomas

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JNK targets p53 ubiquitination and degradation in nonstressed cells

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A transcriptionally active DNA-binding site for human p53 protein complexes

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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The Mdm2 oncoprotein interacts with the cell fate regulator Numb

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Regulation of p53 stability by Mdm2

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Regulation of Mdm2-directed degradation by the C terminus of p53.

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

21 January 2018

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Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

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Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

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Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

21 January 2018

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Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

21 January 2018

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Mammalian p53 can function as a transcription factor in yeast

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

21 January 2018

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DNA sequence analysis of the ade6 gene of Schizosaccharomyces pombe. Wild-type and mutant alleles including the recombination host spot allele ade6-M26.

21 January 2018

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Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

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arg3+, a new selection marker system for Schizosaccharomyces pombe: application of ura4+ as a removable integration marker

21 January 2018

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Defining the minimal requirements for papilloma viral E6-mediated inhibition of human p53 activity in fission yeast.

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

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MDM2 suppresses p73 function without promoting p73 degradation

21 January 2018

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TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility

21 January 2018

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7 January 2021

Mdm2 binding to a conformationally sensitive domain on p53 can be modulated by RNA

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7 January 2021

p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in human tumors

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7 January 2021

Screening patients for heterozygous p53 mutations using a functional assay in yeast

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7 January 2021

Thiamine-repressible expression vectors pREP and pRIP for fission yeast

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Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA

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Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

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The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation.

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11593407%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 November 2019

1052315370

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11593407%20AND%20SRC:MED&resulttype=core&format=json