Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding (Q31014507)

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English	Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

18 October 2017

Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding (English)

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Europe PubMed Central

PMC publication ID

18 October 2017

Karla K Rodgers

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Karla K Rodgers

5

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ORCID Public Data File 2021

author name string

Janeen L Arbuckle

1

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Europe PubMed Central

PMC publication ID

18 October 2017

Negar S Rahman

2

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Europe PubMed Central

PMC publication ID

18 October 2017

Shuying Zhao

3

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Europe PubMed Central

PMC publication ID

18 October 2017

William Rodgers

4

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Europe PubMed Central

PMC publication ID

18 October 2017

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20 May 2011

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Europe PubMed Central

PMC publication ID

18 October 2017

BMC Biochemistry

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Europe PubMed Central

PMC publication ID

18 October 2017

12

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Europe PubMed Central

PMC publication ID

18 October 2017

23

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Europe PubMed Central

PMC publication ID

18 October 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3124419/fullTextXML

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The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3.

1 reference

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The RING domain of RAG1 ubiquitylates histone H3: a novel activity in chromatin-mediated regulation of V(D)J joining

1 reference

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The origins of the Rag genes--from transposition to V(D)J recombination

1 reference

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21 June 2018

Early steps of V(D)J rearrangement: insights from biochemical studies of RAG-RSS complexes.

1 reference

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Assessment of domain boundary predictions and the prediction of intramolecular contacts in CASP8.

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A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity

1 reference

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21 June 2018

Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis

1 reference

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The roles of the RAG1 and RAG2 "non-core" regions in V(D)J recombination and lymphocyte development

1 reference

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21 June 2018

A WW-like module in the RAG1 N-terminal domain contributes to previously unidentified protein-protein interactions

1 reference

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21 June 2018

Full-length RAG1 promotes contact with coding and intersignal sequences in RAG protein complexes bound to recombination signals paired in cis.

1 reference

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21 June 2018

A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2

1 reference

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21 June 2018

Karyopherin alpha 1 is a putative substrate of the RAG1 ubiquitin ligase

1 reference

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21 June 2018

Evidence for Ku70/Ku80 association with full-length RAG1.

1 reference

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21 June 2018

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

1 reference

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21 June 2018

The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2

1 reference

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1 reference

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A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement

1 reference

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The generation of new protein functions by the combination of domains

1 reference

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An ancient evolutionary origin of the Rag1/2 gene locus

1 reference

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21 June 2018

Single-strand recombination signal sequence nicks in vivo: evidence for a capture model of synapsis

1 reference

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21 June 2018

A PHD finger motif in the C terminus of RAG2 modulates recombination activity

1 reference

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21 June 2018

RAG1 core and V(D)J recombination signal sequences were derived from Transib transposons

1 reference

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Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences

1 reference

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1 reference

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Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice

1 reference

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1 reference

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The bounty of RAGs: recombination signal complexes and reaction outcomes

1 reference

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21 June 2018

Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1

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Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

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1 reference

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Autoubiquitylation of the V(D)J recombinase protein RAG1

1 reference

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Full-length RAG-2, and Not Full-length RAG-1, Specifically Suppresses RAG-mediated Transposition but Not Hybrid Joint Formation or Disintegration

1 reference

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Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.

1 reference

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Overlapping signals for protein degradation and nuclear localization define a role for intrinsic RAG-2 nuclear uptake in dividing cells

1 reference

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Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase.

1 reference

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The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer

1 reference

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The RAG1 N-terminal domain is an E3 ubiquitin ligase

1 reference

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Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice

1 reference

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The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

1 reference

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Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination

1 reference

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21 June 2018

A short peptide at the C terminus is responsible for the nuclear localization of RAG2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

V(D)J recombination: RAG proteins, repair factors, and regulation

1 reference

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Transient association of Ku with nuclear substrates characterized using fluorescence photobleaching

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Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex

1 reference

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21 June 2018

High mobility of proteins in the mammalian cell nucleus

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21 June 2018

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

1 reference

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21 June 2018

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

1 reference

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21 June 2018

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

1 reference

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21 June 2018

Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step

1 reference

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1 reference

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1 reference

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Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage

1 reference

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21 June 2018

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1 reference

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21 June 2018

A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2.

1 reference

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21 June 2018

Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3124419

21 June 2018

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1 reference

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21 June 2018

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1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-12-23

21 January 2018

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1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-12-23

21 January 2018

H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations

1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-12-23

21 January 2018

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.

1 reference

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21 January 2018

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21 January 2018

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25 November 2018

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1 reference

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25 November 2018

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

1 reference

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25 November 2018

Cell-free V(D)J recombination

1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-12-23

21 January 2018

Regions of RAG1 protein critical for V(D)J recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/21599978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A zinc-binding domain involved in the dimerization of RAG1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21599978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of a large region of RAG1 that is important for coimmunoprecipitation of RAG2

1 reference

https://pubmed.ncbi.nlm.nih.gov/21599978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of two topologically independent domains in RAG1 and their role in macromolecular interactions relevant to V(D)J recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/21599978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coding joint formation in a cell-free V(D)J recombination system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21599978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21599978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2091-12-23

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

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0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

ResearchGate publication ID

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