Autoubiquitylation of the V(D)J recombinase protein RAG1 (Q28508279)

24 January 2017

title

Autoubiquitylation of the V(D)J recombinase protein RAG1 (English)

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Recombination activating 1

24 January 2017

main subject

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GOA release 2020-03-11

Jessica M. Jones

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24 January 2017

Martin Gellert

series ordinal

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24 January 2017

language of work or name

English

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publication date

23 December 2003

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Proceedings of the National Academy of Sciences of the United States of America

24 January 2017

published in

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24 January 2017

volume

100

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24 January 2017

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24 January 2017

page(s)

15446–15451

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describes a project that uses

24 January 2017

ImageQuant

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC307587/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

19 March 2017

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29 September 2017

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Intermediates in V(D)J recombination: a stable RAG1/2 complex sequesters cleaved RSS ends.

29 September 2017

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V(D)J recombination: links to transposition and double-strand break repair.

29 September 2017

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N-terminal RAG1 frameshift mutations in Omenn's syndrome: internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role in vivo for the N-terminal domains.

29 September 2017

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Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain

29 September 2017

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Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

29 September 2017

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Substrate targeting in the ubiquitin system

29 September 2017

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Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

29 September 2017

1 reference

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Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly

29 September 2017

1 reference

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Complementation of V(D)J recombination deficiency in RAG-1(-/-) B cells reveals a requirement for novel elements in the N-terminus of RAG-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Analysis of regions of RAG-2 important for V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Definition of a core region of RAG-2 that is functional in V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Initiation of V(D)J recombination in a cell-free system.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

The V(D)J recombination activating gene, RAG-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

Formation and resolution of double-strand break intermediates in V(D)J rearrangement

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

RAG2 is down-regulated by cytoplasmic sequestration and ubiquitin-dependent degradation

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2637012100

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2637012100

Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2637012100

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2637012100

N-terminal truncated human RAG1 proteins can direct T-cell receptor but not immunoglobulin gene rearrangements

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307587

A zinc-binding domain involved in the dimerization of RAG1

27 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2637012100

21 January 2018

Identifiers

DOI

10.1073/PNAS.2637012100

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ADS bibcode

2003PNAS..10015446J

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1 reference

1 reference

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