AlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of Tau-Fyn SH3 interaction inhibitors for Alzheimer disease (Q30009327)

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scientific article published on 25 August 2014

Language	Label	Description	Also known as
English	AlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of Tau-Fyn SH3 interaction inhibitors for Alzheimer disease	scientific article published on 25 August 2014

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

AlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of Tau-Fyn SH3 interaction inhibitors for Alzheimer disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

0 references

Alzheimer's disease

1 reference

based on heuristic

inferred from title

bioluminescence

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FYN proto-oncogene, Src family tyrosine kinase

1 reference

GOA release 2020-03-11

identical protein binding

1 reference

GOA release 2020-03-11

0 references

author name string

J Nicholas Cochran

1

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Pauleatha V Diggs

2

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Europe PubMed Central

PubMed publication ID

21 May 2017

N Miranda Nebane

3

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Lynn Rasmussen

4

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

E Lucile White

5

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Robert Bostwick

6

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Joseph A Maddry

7

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Mark J Suto

8

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Erik D Roberson

9

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

publication date

25 August 2014

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Europe PubMed Central

PubMed publication ID

21 May 2017

Journal of Biomolecular Screening

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Europe PubMed Central

PubMed publication ID

21 May 2017

19

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Europe PubMed Central

PubMed publication ID

21 May 2017

10

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Europe PubMed Central

PubMed publication ID

21 May 2017

1338-1349

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4318572/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The dendritic hypothesis for Alzheimer's disease pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Structural polymorphism of 441-residue tau at single residue resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Tau interacts with src-family non-receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

22 May 2017

Seizure resistance without parkinsonism in aged mice after tau reduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Fyn kinase inhibition as a novel therapy for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Antisense reduction of tau in adult mice protects against seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Far-red fluorescent tags for protein imaging in living tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Quantitative comparison of click beetle and firefly luciferases for in vivo bioluminescence imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Medicinal chemical properties of successful central nervous system drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Acquisition of Fyn-selective SH3 domain ligands via a combinatorial library strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Identification and specificity studies of small-molecule ligands for SH3 protein domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Synthetic inhibitors of proline-rich ligand-mediated protein-protein interaction: potent analogs of UCS15A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Higher seizure susceptibility and enhanced tyrosine phosphorylation of N-methyl-D-aspartate receptor subunit 2B in fyn transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Complementary DNA coding click beetle luciferases can elicit bioluminescence of different colors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318572

3 June 2018

Disease-related modifications in tau affect the interaction between Fyn and Tau.

1 reference

https://api.crossref.org/works/10.1177%2F1087057114547232

21 January 2018

Aβ Oligomers Cause Localized Ca2+Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

1 reference

https://api.crossref.org/works/10.1177%2F1087057114547232

21 January 2018

Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation

1 reference

https://api.crossref.org/works/10.1177%2F1087057114547232

21 January 2018

The "jaws" of the tau-microtubule interaction.

1 reference

https://api.crossref.org/works/10.1177%2F1087057114547232

21 January 2018

A Multiple Comparison Procedure for Comparing Several Treatments with a Control

1 reference

https://api.crossref.org/works/10.1177%2F1087057114547232

21 January 2018

Protein-protein interaction inhibitors get into the groove

1 reference

https://pubmed.ncbi.nlm.nih.gov/25156556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fyn tyrosine kinase is required for normal amygdala kindling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25156556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/1087057114547232

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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