Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc. (Q39919668)

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26 December 2019

title

Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc (English)

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26 December 2019

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26 December 2019

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26 December 2019

David Givol

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26 December 2019

Gideon Rechavi

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26 December 2019

Rosa Puca

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26 December 2019

Lavinia Nardinocchi

series ordinal

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26 December 2019

Ada Sacchi

series ordinal

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26 December 2019

language of work or name

English

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publication date

28 October 2008

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Experimental Cell Research

26 December 2019

published in

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26 December 2019

volume

315

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26 December 2019

issue

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26 December 2019

page(s)

67-75

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p53 in health and disease

26 December 2019

cites work

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Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

7 January 2021

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

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Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis

7 January 2021

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Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells.

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Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown

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HIPK2: a multitalented partner for transcription factors in DNA damage response and development.

7 January 2021

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Modulation of p53 protein conformation and DNA-binding activity by intracellular chelation of zinc.

7 January 2021

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Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells

7 January 2021

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Induction, regulation, degradation, and biological significance of mammalian metallothioneins.

7 January 2021

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Zinc deficiency, DNA damage and cancer risk

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Metallothioneins in human tumors and potential roles in carcinogenesis

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Metallothionein expression in human breast cancer

7 January 2021

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Metallothionein 2A expression is associated with cell proliferation in breast cancer

7 January 2021

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Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

7 January 2021

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Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

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Tetracycline-reversible silencing of eukaryotic promoters

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HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations.

7 January 2021

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HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage

7 January 2021

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Metal-responsive elements act as positive modulators of human metallothionein-IIA enhancer activity

7 January 2021

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DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage

7 January 2021

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Enhanced Apoptosis in Metallothionein Null Cells

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YEXCR.2008.10.018

1 reference

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26 December 2019

1 reference

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