Selection of hyperfunctional siRNAs with improved potency and specificity (Q39784931)

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scientific article published on December 2009

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English	Selection of hyperfunctional siRNAs with improved potency and specificity	scientific article published on December 2009

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instance of

scholarly article

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Europe PubMed Central

PMC publication ID

2794195

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14 September 2017

title

Selection of hyperfunctional siRNAs with improved potency and specificity (English)

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Europe PubMed Central

PMC publication ID

2794195

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14 September 2017

author name string

Xiaowei Wang

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1

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PMC publication ID

2794195

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14 September 2017

Xiaohui Wang

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Europe PubMed Central

PMC publication ID

2794195

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14 September 2017

Rajeev K Varma

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2794195

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14 September 2017

Lesslie Beauchamp

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2794195

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14 September 2017

Susan Magdaleno

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5

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2794195

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14 September 2017

Timothy J Sendera

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6

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2794195

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14 September 2017

language of work or name

English

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publication date

1 December 2009

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Europe PubMed Central

PMC publication ID

2794195

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14 September 2017

published in

Nucleic Acids Research

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Europe PubMed Central

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2794195

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14 September 2017

volume

37

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2794195

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14 September 2017

issue

22

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2794195

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14 September 2017

page(s)

e152

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2794195

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14 September 2017

cites work

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Improving model predictions for RNA interference activities that use support vector machine regression by combining and filtering features

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22 September 2017

More complete gene silencing by fewer siRNAs: transparent optimized design and biophysical signature

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22 September 2017

On the art of identifying effective and specific siRNAs

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22 September 2017

Demonstration of two novel methods for predicting functional siRNA efficiency

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22 September 2017

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

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22 September 2017

Computational models with thermodynamic and composition features improve siRNA design

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22 September 2017

Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency.

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22 September 2017

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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22 September 2017

Design of a genome-wide siRNA library using an artificial neural network

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22 September 2017

Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions

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22 September 2017

The contributions of dsRNA structure to Dicer specificity and efficiency

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22 September 2017

siRNA target site secondary structure predictions using local stable substructures

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22 September 2017

Assembly and function of RNA silencing complexes

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22 September 2017

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22 September 2017

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

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22 September 2017

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

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22 September 2017

Rational siRNA design for RNA interference

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22 September 2017

Functional siRNAs and miRNAs Exhibit Strand Bias

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22 September 2017

Asymmetry in the assembly of the RNAi enzyme complex

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PubMed Central

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22 September 2017

Vienna RNA secondary structure server

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PubMed Central

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22 September 2017

Expression profiling reveals off-target gene regulation by RNAi

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PubMed Central

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22 September 2017

RNAi: an ever-growing puzzle

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PubMed Central

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22 September 2017

RNA interference

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PubMed Central

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22 September 2017

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

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22 September 2017

Assessment of the sensitivity and specificity of oligonucleotide (50mer) microarrays

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22 September 2017

Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs

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PubMed Central

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22 September 2017

Analysis of compositionally biased regions in sequence databases

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22 September 2017

Dominant-negative polo-like kinase 1 induces mitotic catastrophe independent of cdc25C function

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25 September 2017

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

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17 June 2018

The impact of target site accessibility on the design of effective siRNAs

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20 August 2018

Sequence characteristics of functional siRNAs

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PubMed Central

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20 August 2018

Prediction of siRNA functionality using generalized string kernel and support vector machine

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PubMed Central

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20 August 2018

Predicting the efficacy of short oligonucleotides in antisense and RNAi experiments with boosted genetic programming.

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20 August 2018

Selection of oligonucleotide probes for protein coding sequences

1 reference

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PubMed Central

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20 August 2018

SIMPLE34: an improved and enhanced implementation for VAX and Sun computers of the SIMPLE algorithm for analysis of clustered repetitive motifs in nucleotide sequences.

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794195

retrieved

20 August 2018

Identifiers

DOI

10.1093/NAR/GKP864

1 reference

stated in

Europe PubMed Central

PMC publication ID

2794195

retrieved

14 September 2017

PMC publication ID

2794195

1 reference

stated in

Europe PubMed Central

PMC publication ID

2794195

retrieved

14 September 2017

PubMed publication ID

19846596

1 reference

stated in

Europe PubMed Central

PMC publication ID

2794195

retrieved

14 September 2017

ResearchGate publication ID

38027476

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