Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma (Q39733997)

14 September 2017

title

Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma (English)

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14 September 2017

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14 September 2017

H Ochiai

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14 September 2017

H Takenobu

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14 September 2017

A Nakagawa

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14 September 2017

Y Yamaguchi

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14 September 2017

M Kimura

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14 September 2017

M Ohira

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14 September 2017

Y Okimoto

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14 September 2017

Y Fujimura

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14 September 2017

Y Kohno

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14 September 2017

A Nakagawara

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14 September 2017

T Kamijo

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14 September 2017

language of work or name

English

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publication date

1 March 2010

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

page(s)

2681-2690

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Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation

14 September 2017

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Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma

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A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation

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Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner

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Bmi-1 is essential for the tumorigenicity of neuroblastoma cells

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Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8

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E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas.

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Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

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Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

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BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas

31 March 2020

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Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblastomas

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E2F proteins regulate MYCN expression in neuroblastomas

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31 March 2020

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The Polycomb group protein EZH2 directly controls DNA methylation

31 March 2020

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Genetic parameters of neuroblastomas

31 March 2020

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Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma

31 March 2020

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Association of epigenetic inactivation of RASSF1A with poor outcome in human neuroblastoma.

31 March 2020

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Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.22

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Dimensions Publication ID

14 September 2017

1042147496

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