Genetic parameters of neuroblastomas (Q34750143)

4 August 2017

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title

Genetic parameters of neuroblastomas (English)

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4 August 2017

Frank Westermann

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4 August 2017

Manfred Schwab

series ordinal

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4 August 2017

language of work or name

English

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publication date

1 October 2002

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4 August 2017

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4 August 2017

volume

184

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4 August 2017

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4 August 2017

page(s)

127-147

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The current contribution of molecular factors to risk estimation in neuroblastoma patients

4 August 2017

cites work

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7 January 2021

Neuroblastoma: current drug therapy recommendations as part of the total treatment approach

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7 January 2021

Why does stage 4s neuroblastoma regress spontaneously?

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7 January 2021

Spontaneous regression of stage IV neuroblastoma

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7 January 2021

Prolonged survival of a patient with disseminated neuroblastoma

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7 January 2021

Mass screening in Japan increased the detection of infants with neuroblastoma without a decrease in cases in older children

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7 January 2021

Which cases are found and missed by neuroblastoma screening at 1 year? Results from the 1992 to 1995 study in three Federal States of Germany

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7 January 2021

Biology and genetics of human neuroblastomas.

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7 January 2021

Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma

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7 January 2021

Flow cytometric DNA analysis of neuroblastoma. Correlation with histology and clinical outcome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

N-myc amplification in neuroblastomas: histopathological, DNA ploidy, and clinical variables

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Disomy 1 with terminal 1p deletion is frequent in mass-screening-negative/late-presenting neuroblastomas in young children, but not in mass-screening-positive neuroblastomas in infants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Cytogenetic findings and prognosis in neuroblastoma with emphasis on marker chromosome 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Prognostic significance of DNA di-tetraploidy in neuroblastoma

1 reference

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7 January 2021

Comparative genomic hybridization (CGH) analysis of neuroblastomas--an important methodological approach in paediatric tumour pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lackingMYCN amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: how many genetic subgroups are there?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Comparative genomic hybridization analysis of human neuroblastomas: detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Comparative genomic hybridization reveals changes in DNA-copy number in poor-risk neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Mechanism and relevance of ploidy in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Managing the centrosome numbers game: from chaos to stability in cancer cell division

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Familial neuroblastoma. Case reports, literature review, and etiologic considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

A general theory of carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Genomic instability in 1p and human malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Chromosomal aberrations in human neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Loss of Heterozygosity at 1p36 Independently Predicts for Disease Progression But Not Decreased Overall Survival Probability in Neuroblastoma Patients: A Children’s Cancer Group Study

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Neuroblastoma consensus deletion maps to 1p36.1-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Constitutional translocation t(1;17)(p36;q12-21) in a patient with neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Detailed molecular analysis of 1p36 in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Smallest region of overlapping deletion in 1p36 in human neuroblastoma: a 1 Mbp cosmid and PAC contig

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Chromosome 1p36 Deletions: The Clinical Phenotype and Molecular Characterization of a Common Newly Delineated Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Terminal deletion of 1p36.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Molecular refinement of the 1p36 deletion syndrome reveals size diversity and a preponderance of maternally derived deletions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

There may be two tumor suppressor genes on chromosome arm 1p closely associated with biologically distinct subtypes of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Two distinct deleted regions on the short arm of chromosome I in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Evidence for two tumour suppressor loci on chromosomal bands 1p35–36 involved in neuroblastoma: one probably imprinted, another associated with N-myc amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Clinical relevance of loss heterozygosity of the short arm of chromosome 1 in neuroblastoma: a single-institution study

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Three chromosomal rearrangements in neuroblastoma cluster within a 300-kb region on 1p36.1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Preferential amplification of the paternal allele of the N-myc gene in human neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Analysis of genomic imprinting at 1p35-36 in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Tumour karyotype discriminates between good and bad prognostic outcome in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Fluorescence in situ hybridization analyses of chromosome band 1p36 in neuroblastoma detect two classes of alterations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

MYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Germline duplication of chromosome 2p and neuroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Trisomy 2p: analysis of unusual phenotypic findings

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

The DDX1 gene maps within 400 kbp 5' to MYCN and is frequently coamplified in human neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

The homeobox gene MEIS1 is amplified in IMR-32 and highly expressed in other neuroblastoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Amplification of N-myc oncogene in stage II and IVS neuroblastomas may be a prognostic indicator

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Clinical implications of oncogene activation in human neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Loss of chromosome 1p may have a prognostic value in localised Neuroblastoma: results of the French NBL 90 study

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Sustained expression of the human protooncogene MYCN rescues rat embryo cells from senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

In vivoregulation of single copy and amplified N-myc in human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

The mycn/max protein complex in neuroblastoma. Short review

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Prognostic significance of MYCN oncogene expression in childhood neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Neoplastic transformation by the human gene N-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

MycN and IFNgamma cooperate in apoptosis of human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

MycN sensitizes neuroblastoma cells for drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Molecular cytogenetic analysis of 1;17 translocations in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Additional copies of a 25 Mb chromosomal region originating from 17q23.1-17qter are present in 90% of high-grade neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Promiscuous translocations of chromosome arm 17q in human neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients. U.K. Children's Cancer Study Group and the U.K. Cancer Cytogenetics Group

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

17q gain in neuroblastoma predicts adverse clinical outcome. U.K. Cancer Cytogenetics Group and the U.K. Children's Cancer Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2(SSTR2) gene at 17q24.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Nm23-H1 mutation in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Neuroblastoma in a boy with MCA/MR syndrome, deletion 11q, and duplication 12q.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

High incidence of constitutional balanced translocations in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Genetics of familial neuroblastoma: long-range studies

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

An increased NM23H1 copy number may be a poor prognostic factor independent of LOH on 1p in neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Deletion of 11q23 is a frequent event in the evolution of MYCN single-copy high-risk neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Allelic deletion at chromosome bands 11q14-23 is common in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Representational difference analysis and loss of heterozygosity studies detect 3p deletions in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Loss of heterozygosity of 3p markers in neuroblastoma tumours implicate a tumour-suppressor locus distal to the FHIT gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Prognostic discrimination among neuroblastomas according to Ha-ras/trk A gene expression: a comparison of the profiles of neuroblastomas detected clinically and those detected through mass screening

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

CpG island methylator phenotype in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

1q23 gain is associated with progressive neuroblastoma resistant to aggressive treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Allelic loss of the short arm of chromosome 4 in neuroblastoma suggests a novel tumour suppressor gene locus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Loss of Heterozygosity at Chromosome 9p21 in Primary Neuroblastomas: Evidence for Two Deleted Regions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Deletion of chromosome 11 and of 14q sequences in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Analysis of loss of heterozygosity at 16p12-p13 (familial neuroblastoma locus) in 470 neuroblastomas including both sporadic and mass screening tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Localization of a hereditary neuroblastoma predisposition gene to 16p12-p13

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900199-4

7 January 2021

10.1016/S0304-3835(02)00199-4

Identifiers

DOI

1 reference

4 August 2017

1 reference