Akt signaling pathway: a target for radiosensitizing human malignant glioma. (Q39712690)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406894%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Akt signaling pathway: a target for radiosensitizing human malignant glioma (English)

1 reference

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31 January 2020

1 reference

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31 January 2020

Gaëlle Loubeau

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31 January 2020

Andreï Tchirkov

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31 January 2020

Jacques Chassagne

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31 January 2020

Claudine Vermot-Desroches

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31 January 2020

Laurent Morel

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31 January 2020

Pierre Verrelle

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31 January 2020

publication date

4 February 2010

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31 January 2020

number of pages

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inferred from page(s)

published in

Neuro-Oncology

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31 January 2020

volume

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31 January 2020

issue

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31 January 2020

page(s)

434-443

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The PI3-K/AKT-pathway and radiation resistance mechanisms in non-small cell lung cancer

31 January 2020

cites work

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation

14 September 2017

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14 September 2017

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The role of IL-6 and STAT3 in inflammation and cancer

14 September 2017

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Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy

14 September 2017

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Immunohistochemically determined total epidermal growth factor receptor levels not of prognostic value in newly diagnosed glioblastoma multiforme: report from the Radiation Therapy Oncology Group

14 September 2017

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

14 September 2017

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Epidemiology and etiology of gliomas

14 September 2017

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Repair of radiation damage to DNA.

14 September 2017

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The STATs of cancer--new molecular targets come of age

14 September 2017

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Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers

14 September 2017

1 reference

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Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice

14 September 2017

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Stats: transcriptional control and biological impact

14 September 2017

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Malignant glioma: genetics and biology of a grave matter.

14 September 2017

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Brain and other central nervous system tumors: rates, trends, and epidemiology.

14 September 2017

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The DNA damage response: putting checkpoints in perspective

14 September 2017

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

14 September 2017

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Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery

14 September 2017

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A Medical Research Council trial of two radiotherapy doses in the treatment of grades 3 and 4 astrocytoma. The Medical Research Council Brain Tumour Working Party

14 September 2017

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Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators

14 September 2017

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PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro

14 September 2017

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JSI-124 inhibits glioblastoma multiforme cell proliferation through G(2)/M cell cycle arrest and apoptosis augment

14 September 2017

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Inhibition of STAT3 promotes the efficacy of adoptive transfer therapy using type-1 CTLs by modulation of the immunological microenvironment in a murine intracranial glioma

14 September 2017

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Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir

14 September 2017

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Macrophages enhance the radiosensitizing activity of lipid A: a novel role for immune cells in tumor cell radioresponse.

14 September 2017

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Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002.

14 September 2017

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Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

14 September 2017

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An analysis of dose-effect relationship in the radiotherapy of malignant gliomas

14 September 2017

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Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation.

14 September 2017

1 reference

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Radiosensitization of human tumor cell lines induced by the adenovirus-mediated expression of an anti-Ras single-chain antibody fragment.

25 September 2017

1 reference

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Interleukin-6 gene amplification and shortened survival in glioblastoma patients.

25 September 2017

1 reference

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Characterization of structurally distinct, isoform-selective phosphoinositide 3'-kinase inhibitors in combination with radiation in the treatment of glioblastoma

17 June 2018

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Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells

20 August 2018

1 reference

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The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas

20 August 2018

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A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

20 August 2018

1 reference

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IL-6 gene amplification and expression in human glioblastomas

20 August 2018

1 reference

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Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture.

20 August 2018

1 reference

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Cancer surveillance series [corrected]: brain and other central nervous system cancers: recent trends in incidence and mortality

20 August 2018

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15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406894

12 December 2020

inferred from PubMed ID database lookup

Studies on the mechanism of phosphatidylinositol 3-kinase inhibition by wortmannin and related analogs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406894

12 December 2020

inferred from PubMed ID database lookup

Malignant glioma: who benefits from adjuvant chemotherapy?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406894

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NEUONC/NOP059

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406894%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

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31 January 2020

PubMed publication ID

20406894

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406894%20AND%20SRC:MED&resulttype=core&format=json