PAI-1 mediates the TGF-beta1+EGF-induced "scatter" response in transformed human keratinocytes (Q39709591)

14 September 2017

PAI-1 mediates the TGF-beta1+EGF-induced "scatter" response in transformed human keratinocytes (English)

1 reference

14 September 2017

1 reference

Jennifer Freytag

1 reference

14 September 2017

Cynthia E Wilkins-Port

1 reference

14 September 2017

Craig E Higgins

1 reference

14 September 2017

Stephen P Higgins

1 reference

14 September 2017

Rohan Samarakoon

1 reference

14 September 2017

Paul J Higgins

1 reference

14 September 2017

language of work or name

English

0 references

publication date

29 April 2010

1 reference

Journal of Investigative Dermatology

14 September 2017

1 reference

14 September 2017

130

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14 September 2017

1 reference

14 September 2017

2179-2190

1 reference

describes a project that uses

14 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3774605/fullTextXML

inferred from PubMed Central ID database lookup

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UV-induced skin cancer: similarities--variations

14 September 2017

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Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis

14 September 2017

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Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Matrix metalloproteinase-1 and -9 activation by plasmin regulates a novel endothelial cell-mediated mechanism of collagen gel contraction and capillary tube regression in three-dimensional collagen matrices.

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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25 September 2017

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25 September 2017

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On the role of c-Jun in the induction of PAI-1 gene expression by phorbol ester, serum, and IL-1alpha in HepG2 cells

25 September 2017

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25 September 2017

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Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion.

25 September 2017

1 reference

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TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

25 September 2017

1 reference

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TGF-beta1 + EGF-initiated invasive potential in transformed human keratinocytes is coupled to a plasmin/MMP-10/MMP-1-dependent collagen remodeling axis: role for PAI-1.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774605

PAI-1 is a Critical Upstream Regulator of the TGF-beta1/EGF-Induced Invasive Phenotype in Mutant p53 Human Cutaneous Squamous Cell Carcinoma

15 June 2018

1 reference

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15 June 2018

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The Myofibroblast Is the Predominant Plasminogen Activator Inhibitor-1-Expressing Cell Type in Human Breast Carcinomas

15 June 2018

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Discriminating expression of differentiation markers evolves in transplants of benign and malignant human skin keratinocytes through stromal interactions

15 June 2018

1 reference

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The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis

15 June 2018

1 reference

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The urokinase-type plasminogen activator system in cancer metastasis: A review

15 June 2018

1 reference

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TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

15 June 2018

1 reference

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p53 mutations in human immortalized epithelial cell lines

15 June 2018

1 reference

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Synergistic effect between EGF and TGF-beta1 in inducing oncogenic properties of intestinal epithelial cells

15 June 2018

1 reference

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Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF-beta1 signaling and EGF as well as FGF receptor tyrosine kinase-ERK pathways in mesenchymal cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774605

Plasminogen activator inhibitor-1 polymorphism is associated with increased risk for oral cancer.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774605

Expression of plasminogen activator inhibitor-1, urokinase receptor and laminin gamma-2 chain is an early coordinated event in incipient oral squamous cell carcinoma

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774605

Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774605

Metastasis is driven by sequential elevation of H-ras and Smad2 levels.

20 August 2018

1 reference

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C-erbB receptors in squamous cell carcinomas of the head and neck: clinical significance and correlation with matrix metalloproteinases and vascular endothelial growth factors.

20 August 2018

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Inducible expression of transforming growth factor beta1 in papillomas causes rapid metastasis.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774605

Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin.

20 August 2018

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Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase-9 expression and in vitro invasion.

20 August 2018

1 reference

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Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3774605

Blocking transforming growth factor beta signaling in transgenic epidermis accelerates chemical carcinogenesis: a mechanism associated with increased angiogenesis

20 August 2018

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12 December 2020

Synergistic effects of epidermal growth factor and hepatocyte growth factor on human ovarian cancer cell invasion and migration: role of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase

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12 December 2020

Fluvastatin inhibits basal and stimulated plasminogen activator inhibitor 1, but induces tissue type plasminogen activator in cultured human endothelial cells

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12 December 2020

Leading-edge myofibroblasts in human colon cancer express plasminogen activator inhibitor-1

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12 December 2020

Ligand release-independent transactivation of epidermal growth factor receptor by transforming growth factor-beta involves multiple signaling pathways.

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12 December 2020

Altered expression of the epidermal growth factor receptor and transforming growth factor-alpha during multistage skin carcinogenesis in SENCAR mice

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12 December 2020

Immunohistochemical localization of urokinase-type plasminogen activator, type-1 plasminogen-activator inhibitor, urokinase receptor and alpha(2)-macroglobulin receptor in human breast carcinomas

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12 December 2020

Plasminogen activator inhibitor-1 as a potential marker for the malignancy of gastric cancer

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12 December 2020

The role of cysteine and serine proteases in colorectal carcinoma

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12 December 2020

Prognostic impact of urokinase, urokinase receptor, and type 1 plasminogen activator inhibitor in squamous and large cell lung cancer tissue

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12 December 2020

Genome-wide profiling of oral squamous cell carcinoma

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12 December 2020

Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth

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12 December 2020

Leading-Edge Myofibroblasts in Human Colon Cancer Express Plasminogen Activator Inhibitor-1

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FJID.2010.106

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/JID.2010.106

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

20428185

1 reference