Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression (Q37318149)

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English	Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

genetic variation

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based on heuristic

inferred from title

2

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Europe PubMed Central

PMC publication ID

19 August 2017

10

object named as

Zena Werb

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Europe PubMed Central

PMC publication ID

19 August 2017

Paul D P Pharoah

4

object named as

Paul D P Pharoah

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Europe PubMed Central

PMC publication ID

19 August 2017

6

object named as

Koei Chin

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Europe PubMed Central

PMC publication ID

19 August 2017

7

object named as

Joe W Gray

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Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Mark D Sternlicht

1

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Europe PubMed Central

PMC publication ID

19 August 2017

Dan H Moore

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

David G Ginzinger

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Frederic M Waldman

8

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Europe PubMed Central

PMC publication ID

19 August 2017

Bruce A J Ponder

9

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Europe PubMed Central

PMC publication ID

19 August 2017

publication date

1 November 2006

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Cancer Epidemiology, Biomarkers & Prevention

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Europe PubMed Central

PMC publication ID

19 August 2017

15

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Europe PubMed Central

PMC publication ID

19 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

2107-2114

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Europe PubMed Central

PMC publication ID

19 August 2017

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Unexpected role of plasminogen activator inhibitor 1 in cell adhesion and detachment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

A gene-expression signature as a predictor of survival in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Clinical utility of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 determination in primary breast cancer tissue for individualized therapy concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Genetic variation in coagulation and fibrinolytic proteins and their relation with acute myocardial infarction: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Association between plasma concentrations of plasminogen activator inhibitor-1 and survival in patients with colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

6 September 2017

Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

14 September 2017

Role of connective growth factor in plasminogen activator inhibitor-1 and fibronectin expression induced by transforming growth factor beta1 in renal tubular cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

14 September 2017

Plasminogen activator inhibitor-1 promotes angiogenesis by stimulating endothelial cell migration toward fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

26 June 2018

Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

26 June 2018

Mutational analysis of the genes encoding urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in advanced ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

26 June 2018

Prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in completely resected gastric cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

26 June 2018

Post-transcriptional regulation of the human transforming growth factor-beta 1 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

26 June 2018

Induction of PAI-1 expression by tumor necrosis factor alpha in endothelial cells is mediated by its responsive element located in the 4G/5G site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Invasion factors uPA/PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Enhanced benefit from adjuvant chemotherapy in breast cancer patients classified high-risk according to urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (n = 3424).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Differential mechanisms of plasminogen activator inhibitor-1 gene activation by transforming growth factor-beta and tumor necrosis factor-alpha in endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Urokinase plasminogen activator and its inhibitor, PAI-1, in association with progression-free survival in early stage endometrial cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Metabolic determinants are much more important than genetic polymorphisms in determining the PAI-1 activity and antigen plasma concentrations: a family study with part of the Stanislas Cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Plasminogen activator inhibitor-1 (PAI-1) promoter polymorphism and coronary artery disease in non-insulin-dependent diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

2 September 2018

Comprehensive Survey of Common Genetic Variation at the Plasminogen Activator Inhibitor-1 Locus and Relations to Circulating Plasminogen Activator Inhibitor-1 Levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731792

3 December 2018

The 4G4G genotype of the plasminogen activator inhibitor 4G/5G gene polymorphism is associated with coronary atherosclerosis in patients at high risk for this disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship of mutations in the MTHFR, prothrombin, and PAI-1 genes to plasma levels of homocysteine, prothrombin, and PAI-1 in children and adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor-1 4G/5G polymorphism in breast cancer patients and its association with tissue PAI-1 levels and tumor severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism is not associated with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complex between urokinase and its type-1 inhibitor in primary breast cancer: relation to survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor 1 (PAI-1) levels and gene promoter polymorphisms in subjects with colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Contribution to Circulating Levels of Hemostatic Factors in Healthy Families With Effects of Known Genetic Polymorphisms on Heritability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor-1 gene polymorphism and colorectal cancer risk and prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of uPA, PAI-1 and PAI-2 mRNA expression in primary breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor 1 (PAI-1) 1334G/A genetic polymorphism in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alternative method for PAI-1 promoter polymorphism (4G/5G) typing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 4G/5G polymorphism of the plasminogen activator inhibitor gene is associated with the time course of progression to acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 4G/5G polymorphism of PAI-1 promoter gene and the risk of myocardial infarction: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17119035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1055-9965.EPI-06-0351

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

release_orvax2i2uzfjlnbajhzmfqdm2e

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https://api.fatcat.wiki/v0/release/orvax2i2uzfjlnbajhzmfqdm2e

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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