FM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways (Q39672963)

13 September 2017

title

FM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways (English)

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13 September 2017

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Francisco Javier Rodríguez-Jiménez

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13 September 2017

Victoria Moreno-Manzano

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13 September 2017

Pablo Mateos-Gregorio

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13 September 2017

Inmaculada Royo

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13 September 2017

Slaven Erceg

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13 September 2017

José Ramón Murguia

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13 September 2017

Jose María Sánchez-Puelles

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13 September 2017

publication date

3 July 2010

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

page(s)

2803-2813

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Centrioles: active players or passengers during mitosis?

13 September 2017

cites work

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Centrioles, centrosomes, and cilia in health and disease

21 January 2018

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Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

21 January 2018

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A mechanism linking extra centrosomes to chromosomal instability

21 January 2018

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Managing the centrosome numbers game: from chaos to stability in cancer cell division

21 January 2018

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Origins and consequences of centrosome aberrations in human cancers

21 January 2018

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Characterisation of breast fine-needle aspiration biopsies by centrosome aberrations and genomic instability

21 January 2018

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Centrosome amplification drives chromosomal instability in breast tumor development

21 January 2018

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Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

21 January 2018

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Centrosome aberrations: cause or consequence of cancer progression?

21 January 2018

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Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

21 January 2018

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Extra centrosomes and/or chromosomes prolong mitosis in human cells

21 January 2018

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Spindle multipolarity is prevented by centrosomal clustering.

21 January 2018

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Centrosome amplification can initiate tumorigenesis in flies.

21 January 2018

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Genetic instabilities in human cancers

21 January 2018

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On the road to cancer: aneuploidy and the mitotic checkpoint

21 January 2018

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The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation

21 January 2018

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The spindle-assembly checkpoint in space and time

21 January 2018

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Examining the link between chromosomal instability and aneuploidy in human cells

21 January 2018

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Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

21 January 2018

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Beyond genetics: surprising determinants of cell fate in antitumor drugs

21 January 2018

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Controlling centrosome number: licenses and blocks

21 January 2018

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Ab ovo or de novo? Mechanisms of centriole duplication

21 January 2018

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Revisiting the role of the mother centriole in centriole biogenesis.

21 January 2018

1 reference

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SAK/PLK4 is required for centriole duplication and flagella development

21 January 2018

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The Polo kinase Plk4 functions in centriole duplication

21 January 2018

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Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis.

21 January 2018

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Constitutive expression of murine Sak-a suppresses cell growth and induces multinucleation

21 January 2018

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Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Plk4-induced centriole biogenesis in human cells

21 January 2018

1 reference

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Plk4 is required for cytokinesis and maintenance of chromosomal stability

21 January 2018

1 reference

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Comparative expression of the mitotic regulators SAK and PLK in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Degradation of activated protein kinases by ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.9.14.12184

The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

21 January 2018

1 reference

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Drosophila skpA, a component of SCF ubiquitin ligases, regulates centrosome duplication independently of cyclin E accumulation

21 January 2018

1 reference

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Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

21 January 2018

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

21 January 2018

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Autophosphorylation of polo-like kinase 4 and its role in centriole duplication

21 January 2018

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Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle

21 January 2018

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Sak/Plk4 and mitotic fidelity

21 January 2018

1 reference

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Merotelic kinetochore orientation, aneuploidy, and cancer.

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040958

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

27 October 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040958

Centrosome hyperamplification predicts progression and tumor recurrence in bladder cancer

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20647763

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Centrosome defects and genetic instability in malignant tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20647763

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.9.14.12184

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PMC publication ID

3040958

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1 reference