A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma (Q39419240)

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English	A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 September 2017

A nonclinical safety and pharmacokinetic evaluation of N6022: a first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma (English)

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Europe PubMed Central

PubMed publication ID

11 September 2017

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pharmacokinetics

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based on heuristic

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author name string

Dorothy B Colagiovanni

1

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11 September 2017

Daniel W Drolet

2

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11 September 2017

Emilie Langlois-Forget

3

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Europe PubMed Central

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11 September 2017

Marie-Pier Piché

4

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11 September 2017

Doug Looker

5

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11 September 2017

Gary J Rosenthal

6

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11 September 2017

language of work or name

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publication date

24 December 2011

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11 September 2017

Regulatory Toxicology and Pharmacology

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11 September 2017

62

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11 September 2017

1

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11 September 2017

115-124

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11 September 2017

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

1 reference

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S-nitrosylation of proteins

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Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid

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Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family

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Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways

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Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile

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Pulmonary complications of intravenous drug misuse. 1. Epidemiology and non-infective complications

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S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme

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Regulation of nitric oxide and soluble guanylyl cyclase

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CeeTox™ Analysis of CNB-001 a Novel Curcumin-Based Neurotrophic/Neuroprotective Lead Compound to Treat Stroke: Comparison with NXY-059 and Radicut

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Endogenous S-nitrosothiols protect against myocardial injury

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S-nitrosylation in cardiovascular signaling

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A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans

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Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock

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A short history of nitroglycerine and nitric oxide in pharmacology and physiology

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Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3

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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1 reference

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Protection from experimental asthma by an endogenous bronchodilator

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Acyl glucuronides: the good, the bad and the ugly.

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Toxicological and pathophysiological roles of reactive oxygen and nitrogen species

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Role of nitric oxide in the biology, physiology and pathophysiology of reproduction

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7 January 2021

Medium- and short-chain dehydrogenase/reductase gene and protein families : Dual functions of alcohol dehydrogenase 3: implications with focus on formaldehyde dehydrogenase and S-nitrosoglutathione reductase activities

1 reference

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7 January 2021

Discovery of S -Nitrosoglutathione Reductase Inhibitors: Potential Agents for the Treatment of Asthma and Other Inflammatory Diseases

1 reference

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7 January 2021

The ontogeny, distribution, and regulation of alcohol dehydrogenase 3: implications for pulmonary physiology

1 reference

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Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2

1 reference

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7 January 2021

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10.1016/J.YRTPH.2011.12.012

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Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

ResearchGate publication ID

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