Idiosyncratic liver toxicity of nonsteroidal antiinflammatory drugs: molecular mechanisms and pathology (Q40422942)

20 September 2017

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title

Idiosyncratic liver toxicity of nonsteroidal antiinflammatory drugs: molecular mechanisms and pathology (English)

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20 September 2017

U A Boelsterli

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20 September 2017

H J Zimmerman

series ordinal

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20 September 2017

A Kretz-Rommel

series ordinal

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20 September 2017

language of work or name

English

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publication date

1 January 1995

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Critical Reviews in Toxicology

20 September 2017

published in

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20 September 2017

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20 September 2017

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20 September 2017

page(s)

207-235

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Idiosyncratic drug reactions: a mechanistic evaluation of risk factors

20 September 2017

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21 January 2018

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Diclofenac inhibits monocyte superoxide production ex vivo in rheumatoid arthritis

21 January 2018

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Nonsteroidal anti-inflammatory drugs: effects on kidney function

21 January 2018

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Another side effect of NSAIDs

21 January 2018

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Hepatitis and non-steroidal anti-inflammatory drugs

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21 January 2018

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The role of non-steroidal anti-inflammatory drugs in acute liver injury

21 January 2018

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CINCHOPHEN—IS THERE A SAFE METHOD OF ADMINISTRATION?

21 January 2018

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IBUFENAC IN THE TREATMENT OF ARTHRITIS

21 January 2018

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IBUFENAC (4-ISOBUTYLPHENYL ACETIC ACID).

21 January 2018

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Phenylbutazone liver injury: A clinical-pathologic survey of 23 cases and review of the literature

21 January 2018

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Diclofenac associated hepatitis

21 January 2018

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21 January 2018

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Fatal hepatitis associated with diclofenac

21 January 2018

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Diclofenac-induced hepatotoxicity

21 January 2018

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Diclofenac-associated hepatotoxicity

21 January 2018

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21 January 2018

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Reversible hepatitis associated with diclofenac

21 January 2018

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Diclofenac induced hepatitis. 3 cases with features of autoimmune chronic active hepatitis

21 January 2018

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Chronic active hepatitis and giant multinucleated hepatocytes in adults treated with clometacin

21 January 2018

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21 January 2018

Sulindac hepatotoxicity

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Sulindac hepatotoxicity: effects of acute and chronic exposure

21 January 2018

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Sulindac-induced Stevens-Johnson toxic epidermal necrolysis syndrome

21 January 2018

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Jaundice associated with naproxen

21 January 2018

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Jaundice associated with naproxen

21 January 2018

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The problems and pitfalls of NSAID therapy in the elderly (Part I).

21 January 2018

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Comparative Efficacy of Pirprofen and Aspirin in Rheumatoid Arthritis

21 January 2018

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Phenylbutazone and hepatitis

21 January 2018

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Piroxicam. A reappraisal of its pharmacology and therapeutic efficacy

21 January 2018

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Emergency liver transplantation for fulminant hepatitis

21 January 2018

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Severe cholestatic jaundice associated with piroxicam

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408449509089888

Piroxicam induced submassive necrosis of the liver

21 January 2018

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The immunologic and metabolic basis of drug hypersensitivities

21 January 2018

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Drug-induced allergic hepatitis

21 January 2018

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Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes

21 January 2018

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Biotransformation of diclofenac sodium (Voltaren) in animals and in man. I. Isolation and identification of principal metabolites

21 January 2018

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Contrasting systemic stabilities of the acyl and phenolic glucuronides of diflunisal in the rat

21 January 2018

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New developments in glucuronidation research: report of a workshop on "glucuronidation, its role in health and disease"

21 January 2018

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Glucuronidation and its Role in Regulation of Biological Activity of Drugs

21 January 2018

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Glucuronidation of drugs. A re-evaluation of the pharmacological significance of the conjugates and modulating factors

21 January 2018

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Acyl glucuronides revisited: is the glucuronidation process a toxification as well as a detoxification mechanism?

21 January 2018

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Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs

21 January 2018

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Protein binding and stereoselectivity of nonsteroidal anti-inflammatory drugs

21 January 2018

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Reversible binding of tolmetin, zomepirac, and their glucuronide conjugates to human serum albumin and plasma

21 January 2018

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Stereoselective interactions of ketoprofen glucuronides with human plasma protein and serum albumin

21 January 2018

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Clinical Pharmacokinetics of Non-steroidal Anti-inflammatory Drugs

21 January 2018

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Predictability of the covalent binding of acidic drugs in man.

21 January 2018

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Irreversible binding of zomepirac to plasma protein in vitro and in vivo

21 January 2018

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Evidence for covalent binding of acyl glucuronides to serum albumin via an imine mechanism as revealed by tandem mass spectrometry

21 January 2018

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Stability of prostacyclin analogues: an unusual lack of reactivity in acid-catalyzed alkene hydration

21 January 2018

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Disposition and irreversible plasma protein binding of tolmetin in humans

21 January 2018

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Pharmacokinetics and irreversible binding of tolmetin and its glucuronic acid esters in the elderly.

21 January 2018

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Studies on the reactivity of acyl glucuronides--V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and beta-glucuronidase.

21 January 2018

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Immunochemical detection of liver protein adducts of the nonsteroidal antiinflammatory drug diclofenac

21 January 2018

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Presence of covalently bound metabolites on rat hepatocyte plasma membrane proteins after administration of isaxonine, a drug leading to immunoallergic hepatitis in man.

21 January 2018

1 reference

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Can hepatocytes serve as 'activated' immunomodulating cells in the immune response?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Drug-induced hepatitis associated with anticytoplasmic organelle autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Cell-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Antibodies to the surface of halothane-altered rabbit hepatocytes in patients with severe halothane-associated hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Antibody mediated hepatocyte injury in methyl dopa induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Anti-cytoskeletal autoantibodies: diagnostic significance for liver diseases, infections and systemic autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Autoimmunity and liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

MHC class-II molecules and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Cross‐reactions of anti‐DNA autoantibodies with cell surface proteins

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408449509089888

The role of autoantibodies in autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Characteristics of clometacin-induced hepatitis with special reference to the presence of anti-actin cable antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Disposition and Metabolism of Benoxaprofen in Laboratory Animals and Man

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408449509089888

Relative toxicities of several nonsteroidal antiinflammatory compounds in primary cultures of rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408449509089888

Interrelationships between xenobiotic metabolism and lipid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Inhibition of hepatic drug-metabolizing enzymes by arachidonic acid

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408449509089888

Conjugation pathways in liver disease

21 January 2018

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Biliary excretion of diflunisal conjugates in patients with T-tube drainage

21 January 2018

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Molecular mimicry of trifluoroacetylated human liver protein adducts by constitutive proteins and immunochemical evidence for its impairment in halothane hepatitis

21 January 2018

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Halothane metabolism: the dihydrolipoamide acetyltransferase subunit of the pyruvate dehydrogenase complex molecularly mimics trifluoroacetyl-protein adducts

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408449509089888

The stereoselective uptake of ibuprofen enantiomers into adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Acute liver injury associated with nonsteroidal anti-inflammatory drugs and the role of risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

Is there a rational basis for the different spectra of adverse effects of nonsteroidal anti-inflammatory drugs (NSAIDs)?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449509089888

21 January 2018

Towards a better aspirin

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10.3109/10408449509089888

21 January 2018

Identifiers

DOI

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20 September 2017

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