Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma. (Q39402899)

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24 March 2020

review article

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title

Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma (English)

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24 March 2020

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24 March 2020

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24 March 2020

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24 March 2020

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24 March 2020

Richard Y Kim

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24 March 2020

Malcolm R Starkey

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24 March 2020

Chantal Donovan

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24 March 2020

Jemma R Mayall

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24 March 2020

Nicole G Hansbro

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24 March 2020

Jodie L Simpson

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24 March 2020

Lisa G Wood

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24 March 2020

Jeremy A Hirota

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24 March 2020

Darryl A Knight

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24 March 2020

Jay C Horvat

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24 March 2020

publication date

1 July 2017

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24 March 2020

published in

Immunological Reviews

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24 March 2020

volume

278

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24 March 2020

issue

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24 March 2020

page(s)

41-62

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The emerging role of microRNAs in regulating immune and inflammatory responses in the lung.

24 March 2020

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21 January 2018

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21 January 2018

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21 January 2018

1 reference

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

21 January 2018

1 reference

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

21 January 2018

1 reference

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

21 January 2018

1 reference

Prolonged reactive oxygen species generation and nuclear factor-kappaB activation after a high-fat, high-carbohydrate meal in the obese.

21 January 2018

1 reference

Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression

21 January 2018

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21 January 2018

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Weight reduction, but not a moderate intake of fish oil, lowers concentrations of inflammatory markers and PAI-1 antigen in obese men during the fasting and postprandial state

21 January 2018

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21 January 2018

1 reference

Postprandial recruitment of neutrophils may contribute to endothelial dysfunction

21 January 2018

1 reference

Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study

21 January 2018

1 reference

Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma

21 January 2018

1 reference

Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress

21 January 2018

1 reference

Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season

21 January 2018

1 reference

Importance of size and composition of particles for effects on cells in vitro

21 January 2018

1 reference

The adjuvant effect of ambient particulate matter is closely reflected by the particulate oxidant potential

21 January 2018

1 reference

Airborne indoor particles from schools are more toxic than outdoor particles

21 January 2018

1 reference

Scanning electron microscopy of immunogold labeled cat allergens (Fel d 1) on the surface of airborne house dust particles

21 January 2018

1 reference

Airborne house dust particles and diesel exhaust particles as allergen carriers

21 January 2018

1 reference

Human airway epithelial cell innate immunity: relevance to asthma

21 January 2018

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Innate immunity in the respiratory epithelium.

21 January 2018

1 reference

Airway epithelial regulation of pulmonary immune homeostasis and inflammation.

21 January 2018

1 reference

Effects of air pollutants on innate immunity: the role of Toll-like receptors and nucleotide-binding oligomerization domain-like receptors

21 January 2018

1 reference

Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles

21 January 2018

1 reference

TLR-2 is involved in airway epithelial cell response to air pollution particles

21 January 2018

1 reference

Ambient particulate matter induces interleukin-8 expression through an alternative NF-κB (nuclear factor-kappa B) mechanism in human airway epithelial cells

21 January 2018

1 reference

Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells

21 January 2018

1 reference

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

21 January 2018

1 reference

Size fractions of ambient particulate matter induce granulocyte macrophage colony-stimulating factor in human bronchial epithelial cells by mitogen-activated protein kinase pathways

21 January 2018

1 reference

Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter

21 January 2018

1 reference

The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.

21 January 2018

1 reference

Diesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3.

21 January 2018

1 reference

TACE/TGF-α/EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components

21 January 2018

1 reference

Cytokine Production by Human Airway Epithelial Cells after Exposure to an Air Pollution Particle Is Metal-Dependent

21 January 2018

1 reference

Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin.

21 January 2018

1 reference

Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin

21 January 2018

1 reference

MicroRNA-375 regulation of thymic stromal lymphopoietin by diesel exhaust particles and ambient particulate matter in human bronchial epithelial cells

21 January 2018

1 reference

Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation

21 January 2018

1 reference

Adjuvant activity of diesel-exhaust particulates for the production of IgE antibody in mice

21 January 2018

1 reference

Diesel-exhaust particulates inoculated by the intranasal route have an adjuvant activity for IgE production in mice

21 January 2018

1 reference

Ozone activates pulmonary dendritic cells and promotes allergic sensitization through a Toll-like receptor 4-dependent mechanism

21 January 2018

1 reference

Radical-containing particles activate dendritic cells and enhance Th17 inflammation in a mouse model of asthma

21 January 2018

1 reference

Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice

21 January 2018

1 reference

Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization.

21 January 2018

1 reference

Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent

21 January 2018

1 reference

Diesel exhaust particles stimulate adaptive immunity by acting on pulmonary dendritic cells.

21 January 2018

1 reference

Activation of pulmonary dendritic cells and Th2-type inflammatory responses on instillation of engineered, environmental diesel emission source or ambient air pollutant particles in vivo

21 January 2018

1 reference

Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation

21 January 2018

1 reference

Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation

21 January 2018

1 reference

IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung.

21 January 2018

1 reference

Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice

21 January 2018

1 reference

Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation.

21 January 2018

1 reference

Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation

21 January 2018

1 reference

Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures

21 January 2018

1 reference

Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel

21 January 2018

1 reference

Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium

21 January 2018

1 reference

Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans.

21 January 2018

1 reference

MicroRNA expression in response to controlled exposure to diesel exhaust: attenuation by the antioxidant N-acetylcysteine in a randomized crossover study

21 January 2018

1 reference

Ozone-induced bronchial epithelial cytokine expression differs between healthy and asthmatic subjects.

21 January 2018

1 reference

Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone

21 January 2018

1 reference

Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers

21 January 2018

1 reference

Patients with asthma demonstrate airway inflammation after exposure to concentrated ambient particulate matter

21 January 2018

1 reference

Diesel exhaust exposure enhances the ozone-induced airway inflammation in healthy humans

21 January 2018

1 reference

Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study

21 January 2018

1 reference

Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers.

21 January 2018

1 reference

Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: results of a double-blinded randomized cross-over clinical pilot study

21 January 2018

1 reference

Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms

21 January 2018

1 reference

Nasal challenge with diesel exhaust particles can induce sensitization to a neoallergen in the human mucosa

21 January 2018

1 reference

Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma

21 January 2018

1 reference

The glutathione-S-transferase mu 1 (GSTM1) null genotype and increased neutrophil response to low-level ozone (0.06 ppm).

21 January 2018

1 reference

Effect of GST variants on lung function following diesel exhaust and allergen co-exposure in a controlled human crossover study

21 January 2018

1 reference

NK Cell Deficiency Predisposes to Viral-Induced Th2-Type Allergic Inflammation via Epithelial-Derived IL-25

21 January 2018

1 reference

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

21 January 2018

1 reference

Animal models of chronic obstructive pulmonary disease

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12543

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28658552%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28658552%20AND%20SRC:MED&resulttype=core&format=json