Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma. (Q39402899)

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scientific article published on July 2017

Language	Label	Description	Also known as
English	Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma.	scientific article published on July 2017

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scholarly article

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24 March 2020

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Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma (English)

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24 March 2020

Philip M Hansbro

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24 March 2020

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Richard Y Kim

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24 March 2020

Malcolm R Starkey

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24 March 2020

Chantal Donovan

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Jemma R Mayall

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24 March 2020

Nicole G Hansbro

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24 March 2020

Jodie L Simpson

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Lisa G Wood

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24 March 2020

Jeremy A Hirota

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24 March 2020

Darryl A Knight

12

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Jay C Horvat

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1 July 2017

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24 March 2020

Immunological Reviews

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24 March 2020

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24 March 2020

1

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24 March 2020

41-62

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24 March 2020

The emerging role of microRNAs in regulating immune and inflammatory responses in the lung.

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21 January 2018

Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts

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21 January 2018

Th2 cytokine antagonists: potential treatments for severe asthma

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21 January 2018

Antiinflammatory action of glucocorticoids--new mechanisms for old drugs

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21 January 2018

Inhaled glucocorticoids for asthma

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21 January 2018

Glucocorticoids

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21 January 2018

Mode of glucocorticoid actions in airway disease.

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21 January 2018

Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells

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21 January 2018

Biochemical basis of asthma therapy

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21 January 2018

Histone deacetylases (HDACs): characterization of the classical HDAC family

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21 January 2018

Mechanisms and resistance in glucocorticoid control of inflammation

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21 January 2018

Glucocorticoid resistance in inflammatory diseases.

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21 January 2018

Effects of dual therapy with corticosteroids plus long acting beta2-agonists in asthma.

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21 January 2018

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21 January 2018

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

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21 January 2018

Steroid Resistance in Bronchial Asthma

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21 January 2018

Steroid resistance in asthma: mechanisms and treatment options

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21 January 2018

Association between neutrophilic airway inflammation and airflow limitation in adults with asthma.

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21 January 2018

Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

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21 January 2018

Cytokine/anti‐cytokine therapy – novel treatments for asthma?

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21 January 2018

IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

1 reference

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21 January 2018

Differences in airway cytokine profile in severe asthma compared to moderate asthma.

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21 January 2018

Pathogenesis of steroid-resistant airway hyperresponsiveness: interaction between IFN-gamma and TLR4/MyD88 pathways.

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21 January 2018

TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice

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21 January 2018

Inflammasomes in COPD and neutrophilic asthma

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21 January 2018

Airway Surfactant Protein D Deficiency in Adults With Severe Asthma

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21 January 2018

Elevated expression of the NLRP3 inflammasome in neutrophilic asthma

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21 January 2018

Innate immune activation in neutrophilic asthma and bronchiectasis.

1 reference

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21 January 2018

Failure of montelukast to reduce sputum eosinophilia in high-dose corticosteroid-dependent asthma

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21 January 2018

Severe asthma: anti-IgE or anti-IL-5?

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21 January 2018

Characterization of asthma endotypes: implications for therapy

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21 January 2018

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia.

1 reference

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21 January 2018

Heterogeneity in mechanisms influencing glucocorticoid sensitivity: the need for a systems biology approach to treatment of glucocorticoid-resistant inflammation.

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21 January 2018

Potential therapeutic targets for steroid-resistant asthma

1 reference

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21 January 2018

Emerging roles of pulmonary macrophages in driving the development of severe asthma

1 reference

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21 January 2018

Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma

1 reference

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21 January 2018

p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma

1 reference

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21 January 2018

Corticosteroid-insensitive asthma: molecular mechanisms.

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21 January 2018

Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients

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21 January 2018

Corticosteroid resistance in airway disease

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21 January 2018

Role of HDAC2 in the pathophysiology of COPD.

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21 January 2018

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

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21 January 2018

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice

1 reference

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21 January 2018

Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma

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21 January 2018

Epithelial cell proliferation contributes to airway remodeling in severe asthma

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21 January 2018

Fibulin-1 is increased in asthma--a novel mediator of airway remodeling?

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21 January 2018

Fibulin1C peptide induces cell attachment and extracellular matrix deposition in lung fibroblasts

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21 January 2018

Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitis

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21 January 2018

LF-15 & T7, synthetic peptides derived from tumstatin, attenuate aspects of airway remodelling in a murine model of chronic OVA-induced allergic airway disease

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21 January 2018

Reduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation, and hyperresponsiveness

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21 January 2018

Airway remodeling and lack of bronchodilator response in steroid-resistant asthma

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21 January 2018

Pulmonary immunity during respiratory infections in early life and the development of severe asthma

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21 January 2018

Murine models of infectious exacerbations of airway inflammation

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21 January 2018

Programming of the lung in early life by bacterial infections predisposes to chronic respiratory disease

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21 January 2018

Understanding the mechanisms of viral induced asthma: new therapeutic directions

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21 January 2018

Childhood asthma after bacterial colonization of the airway in neonates

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21 January 2018

Fetal and Postnatal Development of the Lung

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The relationship between pneumonia in early childhood and impaired lung function in late adult life

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21 January 2018

Role of atypical bacterial infection of the lung in predisposition/protection of asthma.

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21 January 2018

The 'hygiene hypothesis' for autoimmune and allergic diseases: an update

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Emerging pathogenic links between microbiota and the gut-lung axis.

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CD8 T cells and dendritic cells: key players in the attenuated maternal immune response to influenza infection.

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Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation

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21 January 2018

Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7.

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21 January 2018

Adults face increased asthma risk after infant RSV bronchiolitis and reduced respiratory health-related quality of life after RSV pneumonia

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21 January 2018

Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life.

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21 January 2018

Elevated risk of asthma after hospitalization for respiratory syncytial virus infection in infancy

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21 January 2018

Respiratory syncytial virus predisposes mice to augmented allergic airway responses via IL-13-mediated mechanisms

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21 January 2018

Exposure of neonates to respiratory syncytial virus is critical in determining subsequent airway response in adults

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21 January 2018

The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production

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21 January 2018

Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice

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21 January 2018

The Impact of Respiratory Syncytial Virus Disease Prevention on Pediatric Asthma

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21 January 2018

Respiratory-tract colonization and a distinctive pneumonia syndrome in infants infected with Chlamydia trachomatis

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21 January 2018

Pneumonia due to Chlamydia pneumoniae in children: Epidemiology, diagnosis, and treatment

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21 January 2018

Chronic respiratory disease in premature infants caused by Chlamydia trachomatis

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21 January 2018

Chlamydia trachomatis Infections in Neonates and Young Children

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21 January 2018

Chlamydia trachomatis and Chlamydia pneumoniae infections in children and adolescents

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21 January 2018

Chlamydophila pneumoniae and Mycoplasma pneumoniae in respiratory specimens of children with chronic lung diseases

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21 January 2018

The bronchial lavage of pediatric patients with asthma contains infectious Chlamydia

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21 January 2018

Detection of anti-Chlamydia pneumoniae IgE in children with reactive airway disease

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21 January 2018

Chlamydia pneumoniae-specific IgE is prevalent in asthma and is associated with disease severity

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21 January 2018

The development of asthma in wheezing infants with Chlamydia pneumoniae infection

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21 January 2018

Chronic Chlamydia pneumoniae lung infection: a neglected explanation for macrolide effects in wheezing and asthma?

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21 January 2018

Occurrence of Chlamydia trachomatis and Chlamydia pneumoniae in paediatric respiratory infections

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21 January 2018

Neonatal chlamydial infection induces mixed T-cell responses that drive allergic airway disease.

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21 January 2018

Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology

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21 January 2018

Programmed Death Ligand 1 Promotes Early-Life Chlamydia Respiratory Infection-Induced Severe Allergic Airway Disease

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21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease.

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21 January 2018

Constitutive production of IL-13 promotes early-life Chlamydia respiratory infection and allergic airway disease

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21 January 2018

Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice.

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21 January 2018

TLR2, but not TLR4, is required for effective host defence against Chlamydia respiratory tract infection in early life.

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21 January 2018

Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life.

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21 January 2018

The airway microbiome in patients with severe asthma: Associations with disease features and severity.

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21 January 2018

Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment

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21 January 2018

Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma.

1 reference

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21 January 2018

Atypical pathogens and respiratory tract infections

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21 January 2018

Mycoplasma pneumoniae infections

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21 January 2018

Infections caused by Chlamydia pneumoniae strain TWAR

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21 January 2018

Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma

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21 January 2018

Infectious Chlamydia pneumoniae is associated with elevated interleukin-8 and airway neutrophilia in children with refractory asthma

1 reference

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21 January 2018

Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma

1 reference

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21 January 2018

Chlamydia pneumoniae infection enhances cellular proliferation and reduces steroid responsiveness of human peripheral blood mononuclear cells via a tumor necrosis factor-alpha-dependent pathway

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21 January 2018

Chlamydial infection of immune cells: altered function and implications for disease

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21 January 2018

Potentially pathogenic bacteria cultured from the sputum of stable asthmatics are associated with increased 8-isoprostane and airway neutrophilia

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21 January 2018

Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma

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21 January 2018

Association of hospitalizations for asthma with seasonal and pandemic influenza

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21 January 2018

Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma

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21 January 2018

Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease.

1 reference

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21 January 2018

Haemophilus influenzae infection drives IL-17-mediated neutrophilic allergic airways disease

1 reference

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21 January 2018

Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma

1 reference

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21 January 2018

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2.

1 reference

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21 January 2018

Role for NLRP3 Inflammasome-mediated, IL-1β-Dependent Responses in Severe, Steroid-Resistant Asthma.

1 reference

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21 January 2018

Clarithromycin targets neutrophilic airway inflammation in refractory asthma.

1 reference

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21 January 2018

Macrolides for yet another chronic airway disease: severe asthma?

1 reference

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21 January 2018

An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model

1 reference

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21 January 2018

Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma

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21 January 2018

Effect of wortmannin on human eosinophil responses in vitro and on bronchial inflammation and airway hyperresponsiveness in Guinea pigs in vivo

1 reference

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21 January 2018

Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model

1 reference

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21 January 2018

PI3K gamma-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling

1 reference

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21 January 2018

Allergic airway hyperresponsiveness, inflammation, and remodeling do not develop in phosphoinositide 3-kinase gamma-deficient mice.

1 reference

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21 January 2018

Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The contribution of toll-like receptors to the pathogenesis of asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TLR2, TLR4 AND MyD88 Mediate Allergic Airway Disease (AAD) and Streptococcus pneumoniae-Induced Suppression of AAD.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

IL-27/IFN-γ induce MyD88-dependent steroid-resistant airway hyperresponsiveness by inhibiting glucocorticoid signaling in macrophages.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The inflammasomes: guardians of the body

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The inflammasomes

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Inflammasomes: too big to miss

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Inflammasomes in the lung.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Critical functions of priming and lysosomal damage for NLRP3 activation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

A potential role for P2X7R in allergic airway inflammation in mice and humans

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Analysis of NLRP3 in the development of allergic airway disease in mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Inflammasome-IL-1-Th17 response in allergic lung inflammation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally infected mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1β - A Possible Pathway of Exacerbations in COPD

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Influenza virus activates inflammasomes via its intracellular M2 ion channel

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNAs: target recognition and regulatory functions

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Many roads to maturity: microRNA biogenesis pathways and their regulation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNAs as therapeutics for future drug delivery systems in treatment of lung diseases.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The genetic and epigenetic landscapes of the epithelium in asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNAs in inflammatory lung disease--master regulators or target practice?

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Antagonism of miR-328 increases the antimicrobial function of macrophages and neutrophils and rapid clearance of non-typeable Haemophilus influenzae (NTHi) from infected lung

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airway epithelial miRNA expression is altered in asthma.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The PTEN-PI3K pathway: of feedbacks and cross-talks

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Severe asthma: an expanding and mounting clinical challenge

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Dose-response curves to inhaled beta-adrenoceptor agonists in normal and asthmatic subjects

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Chlamydia muridarum infection subverts dendritic cell function to promote Th2 immunity and airways hyperreactivity

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TRAIL signaling is proinflammatory and proviral in a murine model of rhinovirus 1B infection.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TRAIL deficiency and PP2A activation with salmeterol ameliorates egg allergen-driven eosinophilic esophagitis

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Estrogen and progesterone decrease let-7f microRNA expression and increase IL-23/IL-23 receptor signaling and IL-17A production in patients with severe asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TH17 cells in asthma and COPD.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Elucidating novel disease mechanisms in severe asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Harnessing regulatory T cells to suppress asthma: from potential to therapy

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Components of Streptococcus pneumoniae suppress allergic airways disease and NKT cells by inducing regulatory T cells.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Pneumococcal components induce regulatory T cells that attenuate the development of allergic airways disease by deviating and suppressing the immune response to allergen.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Asthma is associated with weight gain in females but not males, independent of physical activity

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Body mass index and asthma incidence among USA adults

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Prospective study of body mass index, weight change, and risk of adult-onset asthma in women

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Effect of weight reduction on respiratory function and airway reactivity in obese women.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Influence of excess adiposity on exercise fitness and performance in overweight children and adolescents

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Dietary factors lead to innate immune activation in asthma.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Exhaled nitric oxide is increased in asthma.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

No significant relationship between exhaled nitric oxide and body mass index in people with asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The relation between obesity and asthmatic airway inflammation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airway inflammation in obese and nonobese patients with difficult-to-treat asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Obesity and asthma: a specific phenotype?

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Obesity in asthma: more neutrophilic inflammation as a possible explanation for a reduced treatment response.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airway inflammation is augmented by obesity and fatty acids in asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Influence of body mass index on the response to asthma controller agents

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Prolonged reactive oxygen species generation and nuclear factor-kappaB activation after a high-fat, high-carbohydrate meal in the obese.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Weight reduction, but not a moderate intake of fish oil, lowers concentrations of inflammatory markers and PAI-1 antigen in obese men during the fasting and postprandial state

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Postprandial variations of plasma inflammatory markers in abdominally obese men.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Postprandial recruitment of neutrophils may contribute to endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Importance of size and composition of particles for effects on cells in vitro

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The adjuvant effect of ambient particulate matter is closely reflected by the particulate oxidant potential

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airborne indoor particles from schools are more toxic than outdoor particles

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Scanning electron microscopy of immunogold labeled cat allergens (Fel d 1) on the surface of airborne house dust particles

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airborne house dust particles and diesel exhaust particles as allergen carriers

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Human airway epithelial cell innate immunity: relevance to asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Innate immunity in the respiratory epithelium.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airway epithelial regulation of pulmonary immune homeostasis and inflammation.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Effects of air pollutants on innate immunity: the role of Toll-like receptors and nucleotide-binding oligomerization domain-like receptors

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TLR-2 is involved in airway epithelial cell response to air pollution particles

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Ambient particulate matter induces interleukin-8 expression through an alternative NF-κB (nuclear factor-kappa B) mechanism in human airway epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Size fractions of ambient particulate matter induce granulocyte macrophage colony-stimulating factor in human bronchial epithelial cells by mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

TACE/TGF-α/EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Cytokine Production by Human Airway Epithelial Cells after Exposure to an Air Pollution Particle Is Metal-Dependent

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA-375 regulation of thymic stromal lymphopoietin by diesel exhaust particles and ambient particulate matter in human bronchial epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Adjuvant activity of diesel-exhaust particulates for the production of IgE antibody in mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel-exhaust particulates inoculated by the intranasal route have an adjuvant activity for IgE production in mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Ozone activates pulmonary dendritic cells and promotes allergic sensitization through a Toll-like receptor 4-dependent mechanism

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Radical-containing particles activate dendritic cells and enhance Th17 inflammation in a mouse model of asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel exhaust particles stimulate adaptive immunity by acting on pulmonary dendritic cells.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Activation of pulmonary dendritic cells and Th2-type inflammatory responses on instillation of engineered, environmental diesel emission source or ambient air pollutant particles in vivo

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

MicroRNA expression in response to controlled exposure to diesel exhaust: attenuation by the antioxidant N-acetylcysteine in a randomized crossover study

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Ozone-induced bronchial epithelial cytokine expression differs between healthy and asthmatic subjects.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Patients with asthma demonstrate airway inflammation after exposure to concentrated ambient particulate matter

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel exhaust exposure enhances the ozone-induced airway inflammation in healthy humans

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: Effects on inflammatory lung markers.

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: results of a double-blinded randomized cross-over clinical pilot study

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Nasal challenge with diesel exhaust particles can induce sensitization to a neoallergen in the human mucosa

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

The glutathione-S-transferase mu 1 (GSTM1) null genotype and increased neutrophil response to low-level ozone (0.06 ppm).

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Effect of GST variants on lung function following diesel exhaust and allergen co-exposure in a controlled human crossover study

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

NK Cell Deficiency Predisposes to Viral-Induced Th2-Type Allergic Inflammation via Epithelial-Derived IL-25

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Animal models of chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1111%2FIMR.12543

21 January 2018

Identifiers

10.1111/IMR.12543

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28658552%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28658552%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

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