Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation. (Q39185480)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23459942%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation (English)

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24 February 2020

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24 February 2020

Ken Blackwell

1 reference

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24 February 2020

Laiqun Zhang

1 reference

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24 February 2020

Lauren M Workman

1 reference

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24 February 2020

Adrian T Ting

1 reference

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24 February 2020

Hasem Habelhah

1 reference

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24 February 2020

language of work or name

English

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publication date

4 March 2013

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Molecular and Cellular Biology

24 February 2020

published in

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24 February 2020

volume

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24 February 2020

issue

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24 February 2020

page(s)

1901-1915

1 reference

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No one can whistle a symphony alone - how different ubiquitin linkages cooperate to orchestrate NF-κB activity

24 February 2020

cites work

1 reference

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IAPs limit activation of RIP kinases by TNF receptor 1 during development

10 September 2017

1 reference

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cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

10 September 2017

1 reference

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HOIL-1L interacting protein (HOIP) is essential for CD40 signaling

10 September 2017

1 reference

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Linear ubiquitination prevents inflammation and regulates immune signalling

10 September 2017

1 reference

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In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8

10 September 2017

1 reference

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TNFR1-induced activation of the classical NF-κB pathway

10 September 2017

1 reference

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Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

10 September 2017

1 reference

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Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.

10 September 2017

1 reference

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Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

10 September 2017

1 reference

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Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

10 September 2017

1 reference

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A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

10 September 2017

1 reference

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Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2

10 September 2017

1 reference

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Breaking the chains: structure and function of the deubiquitinases

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Linear polyubiquitination: a new regulator of NF-kappaB activation.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Regulation and function of NF-kappaB transcription factors in the immune system

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Nonproteolytic functions of ubiquitin in cell signaling

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

TNF-alpha induces two distinct caspase-8 activation pathways

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Control of canonical NF-kappaB activation through the NIK-IKK complex pathway

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Shared principles in NF-kappaB signaling

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

10 September 2017

1 reference

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Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

10 September 2017

1 reference

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Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases

10 September 2017

1 reference

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

10 September 2017

1 reference

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Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

10 September 2017

1 reference

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The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

10 September 2017

1 reference

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RING finger proteins: mediators of ubiquitin ligase activity

10 September 2017

1 reference

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

10 September 2017

1 reference

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Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific

10 September 2017

1 reference

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Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

TRAF2 suppresses basal IKK activity in resting cells and TNFalpha can activate IKK in TRAF2 and TRAF5 double knockout cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Genetic analysis of NF- B/Rel transcription factors defines functional specificities

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Two waves of nuclear factor kappaB recruitment to target promoters

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647962

2 December 2018

Identifiers

DOI

10.1128/MCB.01416-12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23459942%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

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24 February 2020

PubMed publication ID

23459942

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23459942%20AND%20SRC:MED&resulttype=core&format=json