Biomolecular condensates: organizers of cellular biochemistry (Q39146409)

9 September 2017

title

Biomolecular condensates: organizers of cellular biochemistry (English)

1 reference

9 September 2017

Salman F Banani

1 reference

9 September 2017

Hyun O Lee

series ordinal

1 reference

9 September 2017

Anthony A Hyman

series ordinal

1 reference

9 September 2017

Michael K Rosen

series ordinal

1 reference

9 September 2017

publication date

22 February 2017

1 reference

Nature Reviews Molecular Cell Biology

9 September 2017

published in

1 reference

9 September 2017

1 reference

9 September 2017

1 reference

9 September 2017

page(s)

285-298

1 reference

Biogenesis and function of nuclear bodies

9 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

P-bodies and stress granules: possible roles in the control of translation and mRNA degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Higher-order assemblies in a new paradigm of signal transduction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

In vivo kinetics of Cajal body components

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

High mobility of proteins in the mammalian cell nucleus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Dynamics of component exchange at PML nuclear bodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

In vivo analysis of Cajal body movement, separation, and joining in live human cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Nuclear aggresomes form by fusion of PML-associated aggregates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Live cell dynamics of promyelocytic leukemia nuclear bodies upon entry into and exit from mitosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

The number of PML nuclear bodies increases in early S phase by a fission mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Germline P granules are liquid droplets that localize by controlled dissolution/condensation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Liquid-liquid phase separation in biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase transitions in the assembly of multivalent signalling proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase transitions of multivalent proteins can promote clustering of membrane receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase separation of signaling molecules promotes T cell receptor signal transduction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

In Vitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Compositional Control of Phase-Separated Cellular Bodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Vascular effects of a low-carbohydrate high-protein diet.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Molecular-level engineering of protein physical hydrogels for predictive sol-gel phase behavior

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Polymer physics of intracellular phase transitions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

RNA Controls PolyQ Protein Phase Transitions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Stress granule assembly is mediated by prion-like aggregation of TIA-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

A role for Q/N-rich aggregation-prone regions in P-body localization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase transition of spindle-associated protein regulate spindle apparatus assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

The LC Domain of hnRNPA2 Adopts Similar Conformations in Hydrogel Polymers, Liquid-like Droplets, and Nuclei

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Inverse size scaling of the nucleolus by a concentration-dependent phase transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Nucleation of nuclear bodies by RNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

De novo formation of a subnuclear body

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

RNA transcription modulates phase transition-driven nuclear body assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

A role for macromolecular crowding effects in the assembly and function of compartments in the nucleus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Mitotic accumulations of PML protein contribute to the re-establishment of PML nuclear bodies in G1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Robust heat shock induces eIF2alpha-phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast, Saccharomyces cerevisiae.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Eukaryotic stress granules: the ins and outs of translation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Stress-dependent relocalization of translationally primed mRNPs to cytoplasmic granules that are kinetically and spatially distinct from P-bodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Amyloid-like Self-Assembly of a Cellular Compartment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Amyloid fibrils from muscle myoglobin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Quantitative characterization of intrinsic disorder in polyglutamine: insights from analysis based on polymer theories

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

A glass menagerie of low complexity sequences.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Altered ribostasis: RNA-protein granules in degenerative disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Stress granules as crucibles of ALS pathogenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Getting RNA and protein in phase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Phase Separation: Linking Cellular Compartmentalization to Disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Are aberrant phase transitions a driver of cellular aging?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

A unique configuration of genome-wide DNA methylation patterns in the testis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Spatial Organization of the Cell Cytoplasm by Position-Dependent Phase Separation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Suppression of Ostwald ripening in active emulsions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Emergent self-organization in active materials

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Spontaneous motion in hierarchically assembled active matter

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Three-dimensional organization of promyelocytic leukemia nuclear bodies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

The multifunctional nucleolus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Fine structural organization of the interphase nucleus in some mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Beyond Oil and Water--Phase Transitions in Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

In vivo kinetics of U4/U6·U5 tri-snRNP formation in Cajal bodies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

RNA catalysis through compartmentalization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Small Cajal body-specific RNAs of Drosophila function in the absence of Cajal bodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Colocalization and Sequential Enzyme Activity in Aqueous Biphasic Systems: Experiments and Modeling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Beyond the excluded volume effects: mechanistic complexity of the crowded milieu

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Mobility of Nonsticky Nanoparticles in Polymer Liquids.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Scaffold proteins: hubs for controlling the flow of cellular information

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Enzyme clustering accelerates processing of intermediates through metabolic channeling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Dynamic reorganization of metabolic enzymes into intracellular bodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Common regulatory control of CTP synthase enzyme activity and filament formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Functional roles for noise in genetic circuits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Identification of Edc3p as an enhancer of mRNA decapping in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Role of PML and the PML-nuclear body in the control of programmed cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Molecular distribution in condensation polymers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Thermoreversible Gelation in Solutions of Associative Polymers. 1. Statics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.7

Physiological protein aggregation run amuck: stress granules and the genesis of neurodegenerative disease

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28225081

12 December 2020

inferred from PubMed ID database lookup

Two-component protein-engineered physical hydrogels for cell encapsulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28225081

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/28225081

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NRM.2017.7

1 reference

release_l7psgqoicff3bop3bcoqxhfo5a

9 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/l7psgqoicff3bop3bcoqxhfo5a

24 November 2022

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/l7psgqoicff3bop3bcoqxhfo5a

24 November 2022

mapped directly with Wikidata item

1 reference