Prospective virtual screening for novel p53-MDM2 inhibitors using ultrafast shape recognition (Q39022371)

8 September 2017

title

Prospective virtual screening for novel p53-MDM2 inhibitors using ultrafast shape recognition (English)

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8 September 2017

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24554192%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Sachin P Patil

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24554192%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Cassidy R Kerezsi

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24554192%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

20 February 2014

1 reference

Journal of Computer - Aided Molecular Design

8 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24554192%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

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6 June 2020

issue

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6 June 2020

page(s)

89-97

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24554192%20AND%20SRC:MED&resulttype=core&format=json

The p53 pathway: positive and negative feedback loops

6 June 2020

cites work

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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21 January 2018

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Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

21 January 2018

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Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

21 January 2018

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Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

21 January 2018

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Identification of FDA-approved drugs that computationally bind to MDM2

21 January 2018

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Ultrafast shape recognition: method and applications

21 January 2018

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Ultrafast shape recognition to search compound databases for similar molecular shapes

21 January 2018

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Hierarchical virtual screening for the discovery of new molecular scaffolds in antibacterial hit identification

21 January 2018

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Prospective virtual screening with Ultrafast Shape Recognition: the identification of novel inhibitors of arylamine N-acetyltransferases

21 January 2018

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ZINC--a free database of commercially available compounds for virtual screening

21 January 2018

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Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery.

21 January 2018

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21 January 2018

The Protein Data Bank

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Structural determinants of benzodiazepinedione/peptide-based p53-HDM2 inhibitors using 3D-QSAR, docking and molecular dynamics

21 January 2018

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The Structure‐Based Design of Mdm2/Mdmx–p53 Inhibitors Gets Serious

21 January 2018

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The tumor suppressor p53: from structures to drug discovery

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Optimization of high throughput virtual screening by combining shape-matching and docking methods

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Novel procedure for modeling ligand/receptor induced fit effects.

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Isoquinolin-1-one inhibitors of the MDM2-p53 interaction

21 January 2018

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Therapeutic targeting of angiotensin II receptor type 1 to regulate androgen receptor in prostate cancer

21 January 2018

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The MDM2-p53 interaction.

21 January 2018

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12 December 2020

Telmisartan as a peroxisome proliferator-activated receptor-γ ligand is a new target in the treatment of human renal cell carcinoma

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12 December 2020

Small-molecule antagonists of p53-MDM2 binding: research tools and potential therapeutics.

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12 December 2020

Discovery of highly potent p53-MDM2 antagonists and structural basis for anti-acute myeloid leukemia activities.

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12 December 2020

Telmisartan inhibits human urological cancer cell growth through early apoptosis

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12 December 2020

Ultrafast shape recognition: Evaluating a new ligand-based virtual screening technology

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12 December 2020

10.1007/S10822-014-9732-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24554192%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

DBLP publication ID

journals/jcamd/PatilBK14

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24554192%20AND%20SRC:MED&resulttype=core&format=json