The neonatal immune system: immunomodulation of infections in early life (Q39014478)

8 September 2017

title

The neonatal immune system: immunomodulation of infections in early life (English)

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8 September 2017

Eliana Akemi Futata

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8 September 2017

Ana Elisa Fusaro

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8 September 2017

Cyro Alves de Brito

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8 September 2017

Maria Notomi Sato

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8 September 2017

publication date

1 March 2012

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Expert Review of Anti-infective Therapy

8 September 2017

published in

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8 September 2017

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8 September 2017

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8 September 2017

page(s)

289-298

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Estimating the causes of 4 million neonatal deaths in the year 2000.

8 September 2017

cites work

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The neonatal blood count in health and disease.I. Reference values for neutrophilic cells

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Impaired innate immunity in the newborn: newborn neutrophils are deficient in bactericidal/permeability-increasing protein.

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Neonatal innate immunity to infectious agents

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Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis.

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Toll-like receptors and dendritic cells: for whom the bug tolls

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Toll-like receptors and acquired immunity

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A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells

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Preferential production of the IL-12(p40)/IL-23(p19) heterodimer by dendritic cells from human newborns.

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Molecular mechanisms underlying anti-inflammatory phenotype of neonatal splenic macrophages

21 January 2018

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Innate cellular immune responses in newborns

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Acquisition of adult-like TLR4 and TLR9 responses during the first year of life

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Impaired responses to toll-like receptor 4 and toll-like receptor 3 ligands in human cord blood

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Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life.

21 January 2018

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Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes.

21 January 2018

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Expression of cytokine-associated genes in dendritic cells (DCs): comparison between adult peripheral blood- and umbilical cord blood-derived DCs by cDNA microarray.

21 January 2018

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Dendritic cell immaturity during infancy restricts the capacity to express vaccine-specific T-cell memory

21 January 2018

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Neonatal innate TLR-mediated responses are distinct from those of adults.

21 January 2018

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Innate immunity of the human newborn is polarized toward a high ratio of IL-6/TNF-alpha production in vitro and in vivo

21 January 2018

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Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848.

21 January 2018

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The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn.

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Impaired innate and adaptive immunity to Streptococcus pneumoniae and its effect on colonization in an infant mouse model

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Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans.

21 January 2018

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CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene.

21 January 2018

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Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

21 January 2018

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Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses

21 January 2018

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CD28/B7 system of T cell costimulation

21 January 2018

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Neonatal Tolerance: Towards an Immunogenetic Definition of Self

21 January 2018

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Generation of adult-like antibody avidity profiles after early-life immunization with protein vaccines

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Genetic immunization of neonates

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Predominant autoantibody production by early human B cell precursors

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Peripheral development of B cells in mouse and man.

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APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

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Maternal antibodies, childhood infections, and autoimmune diseases

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Clinical microbiology of bacterial and fungal sepsis in very-low-birth-weight infants

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Long-term trends in the epidemiology of neonatal sepsis and antibiotic susceptibility of causative agents.

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Defective macrophage function in neonates and its impact on unresponsiveness of neonates to polysaccharide antigens

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Listeria monocytogenes: clinical and experimental update

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Enhancement of neonatal innate defense: effects of adding an N-terminal recombinant fragment of bactericidal/permeability-increasing protein on growth and tumor necrosis factor-inducing activity of gram-negative bacteria tested in neonatal cord bloo

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Interactions of alpha-, beta-, and theta-defensins with influenza A virus and surfactant protein D.

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Effect of antibacterial cathelicidin peptide CAP18/LL-37 on sepsis in neonatal rats.

21 January 2018

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Recent advances in prevention of sepsis in the premature neonates in NICU.

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Lactoferrin for prevention of neonatal infections

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Lactoferrin—a multifunctional protein with antimicrobial properties

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Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties

21 January 2018

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Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists.

21 January 2018

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Low birth weight infants and Calmette-Guérin bacillus vaccination at birth: community study from Guinea-Bissau

21 January 2018

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Yersinia enterocolitica promotes robust mucosal inflammatory T-cell immunity in murine neonates

21 January 2018

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Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidates

21 January 2018

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The advantage of mucosal immunization for polysaccharide-specific memory responses in early life.

21 January 2018

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Selective enhancement of systemic Th1 immunity in immunologically immature rats with an orally administered bacterial extract

21 January 2018

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Exogenous heat-killed Escherichia coli improves alveolar macrophage activity and reduces Pneumocystis carinii lung burden in infant mice

21 January 2018

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Probiotics prevent death caused by Citrobacter rodentium infection in neonatal mice

21 January 2018

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Tolerance rather than immunity protects from Helicobacter pylori-induced gastric preneoplasia

21 January 2018

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Asthma exacerbations. 2: aetiology

21 January 2018

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The role of T cells in the enhancement of respiratory syncytial virus infection severity during adult reinfection of neonatally sensitized mice

21 January 2018

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Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life.

21 January 2018

1 reference

The Acquisition of Herpes Simplex Virus during Pregnancy

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Neuropathogenesis of congenital cytomegalovirus infection: disease mechanisms and prospects for intervention

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Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments.

21 January 2018

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Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection

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CD4(+) T cell responses to cytomegalovirus in early life: a prospective birth cohort study

21 January 2018

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A proviral role for CpG in cytomegalovirus infection.

21 January 2018

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Adoptive transfer studies demonstrating the antiviral effect of natural killer cells in vivo

21 January 2018

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Adaptive immune features of natural killer cells

21 January 2018

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Immunomodulation with IL-4R alpha antisense oligonucleotide prevents respiratory syncytial virus-mediated pulmonary disease.

21 January 2018

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Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells

21 January 2018

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Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes

21 January 2018

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Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes

21 January 2018

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Immune adjuvants in early life: targeting the innate immune system to overcome impaired adaptive response

21 January 2018

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Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs

21 January 2018

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Immunological mechanisms of vaccination

21 January 2018

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New adjuvants for human vaccines

21 January 2018

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Vaccine Adjuvants: Putting Innate Immunity to Work

21 January 2018

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Hyper innate responses in neonates lead to increased morbidity and mortality after infection

21 January 2018

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IL-12 and type I IFN response of neonatal myeloid DC to human CMV infection

21 January 2018

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TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver

21 January 2018

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3 January 2024

https://opencitations.net/index/api/v1/citations/10.1182/BLOOD-2004-08-3262

Identifiers

DOI

10.1586/ERI.12.9

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8 September 2017

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