Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-β/Smad signaling pathway (Q38975175)

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English	Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-β/Smad signaling pathway	scientific article

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scholarly article

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Europe PubMed Central

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8 September 2017

Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-β/Smad signaling pathway (English)

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Europe PubMed Central

PMC publication ID

8 September 2017

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Jiang Geng

1

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8 September 2017

Jie Fan

2

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8 September 2017

Qi Ouyang

3

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8 September 2017

Xiaopeng Zhang

4

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8 September 2017

Xiaolong Zhang

5

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8 September 2017

Juan Yu

6

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8 September 2017

Zude Xu

7

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8 September 2017

Qianyu Li

8

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8 September 2017

Xudong Yao

9

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8 September 2017

Xiuping Liu

10

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8 September 2017

Junhua Zheng

11

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8 September 2017

language of work or name

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publication date

1 July 2014

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8 September 2017

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Europe PubMed Central

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8 September 2017

5

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8 September 2017

14

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Europe PubMed Central

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8 September 2017

5700-5711

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Europe PubMed Central

PMC publication ID

8 September 2017

Identification of a Novel Compound That Suppresses Breast Cancer Invasiveness by Inhibiting Transforming Growth Factor-β Signaling via Estrogen Receptor α.

1 reference

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9 September 2017

EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Cancer statistics, 2013

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Genetic variations in the transforming growth factor beta pathway as predictors of bladder cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

TGFβ1 induces apoptosis in invasive prostate cancer and bladder cancer cells via Akt-independent, p38 MAPK and JNK/SAPK-mediated activation of caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Regulation of MMP-9 by p53 in first trimester cytotrophoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Expression of PTEN, PPM1A and P-Smad2 in hepatocellular carcinomas and adjacent liver tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Termination of TGF-beta superfamily signaling through SMAD dephosphorylation--a functional genomic view

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Muscle-invasive urothelial carcinoma of the bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Superficial and muscle-invasive bladder cancer: principles of management for outcomes assessments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Transcriptional regulation of cadherins during development and carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Epithelial-mesenchymal transitions in tumour progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

TGF-beta signaling: positive and negative effects on tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Predictive value of expression of transforming growth factor-beta(1) and its receptors in transitional cell carcinoma of the urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

TGF-beta signaling in cancer--a double-edged sword

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

PPM1A is a RelA phosphatase with tumor suppressor-like activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

9 September 2017

Coupling of dephosphorylation and nuclear export of Smads in TGF-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

14 September 2017

Combination effect of a TGF-beta receptor kinase inhibitor with 5-FU analog S1 on lymph node metastasis of scirrhous gastric cancer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

14 September 2017

Protein phosphatase 1A (PPM1A) is involved in human cytotrophoblast cell invasion and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

14 September 2017

Sp1 is required for transforming growth factor-beta-induced mesenchymal transition and migration in pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

14 September 2017

Involvement of MAPK pathway in TNF-alpha-induced MMP-9 expression in human trophoblastic cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

14 September 2017

Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells

1 reference

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14 September 2017

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

1 reference

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17 June 2018

Regulation of transforming growth factor-beta 1-induced apoptosis and epithelial-to-mesenchymal transition by protein kinase A and signal transducers and activators of transcription 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4170610

21 August 2018

Silencing of FABP3 promotes apoptosis and induces mitochondrion impairment in embryonic carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25026293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factors-beta 1 and beta 2 in serum and urine from patients with bladder carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25026293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/25026293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Expression and significance of LMP2 and PPM1A in gestational trophoblastic disease]

1 reference

https://pubmed.ncbi.nlm.nih.gov/25026293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

REG1A predicts recurrence in stage Ta/T1 bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25026293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preoperative plasma levels of transforming growth factor beta(1) strongly predict clinical outcome in patients with bladder carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25026293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.2144

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

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