Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities (Q38725778)

http://europepmc.org/abstract/PMC/5270474

22 February 2018

title

Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities (English)

1 reference

http://europepmc.org/abstract/PMC/5270474

22 February 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Carolyn G Sweeney

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Bradford P Tremblay

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Thomas Stockner

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Harald H Sitte

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

16 December 2016

1 reference

http://europepmc.org/abstract/PMC/5270474

22 February 2018

published in

Journal of Biological Chemistry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

292

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7 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

1302-1309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters

7 June 2020

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23 June 2018

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Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain

23 June 2018

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Differential Internalization Rates and Postendocytic Sorting of the Norepinephrine and Dopamine Transporters Are Controlled by Structural Elements in the N Termini.

23 June 2018

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23 June 2018

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23 June 2018

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Spontaneous inward opening of the dopamine transporter is triggered by PIP2-regulated dynamics of the N-terminus

23 June 2018

1 reference

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23 June 2018

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A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter

23 June 2018

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Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors

23 June 2018

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Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2 -containing membranes.

23 June 2018

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Amphetamines, new psychoactive drugs and the monoamine transporter cycle.

23 June 2018

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Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.

23 June 2018

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PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

23 June 2018

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Antagonist-induced conformational changes in dopamine transporter extracellular loop two involve residues in a potential salt bridge

23 June 2018

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X-ray structure of dopamine transporter elucidates antidepressant mechanism

23 June 2018

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Mechanisms of dopamine transporter regulation in normal and disease states

23 June 2018

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Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

23 June 2018

1 reference

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Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

23 June 2018

1 reference

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A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter

23 June 2018

1 reference

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Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

23 June 2018

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Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding

23 June 2018

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Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation

23 June 2018

1 reference

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SLC6 neurotransmitter transporters: structure, function, and regulation

23 June 2018

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The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

23 June 2018

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Site-Directed Mutations near Transmembrane Domain 1 Alter Conformation and Function of Norepinephrine and Dopamine Transporters

23 June 2018

1 reference

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The N terminus of monoamine transporters is a lever required for the action of amphetamines

23 June 2018

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23 June 2018

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Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues

23 June 2018

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A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

23 June 2018

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23 June 2018

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23 June 2018

1 reference

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An intracellular interaction network regulates conformational transitions in the dopamine transporter.

23 June 2018

1 reference

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Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D.

23 June 2018

1 reference

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Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter

23 June 2018

1 reference

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Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase

23 June 2018

1 reference

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23 June 2018

1 reference

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Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

Sodium-dependent neurotransmitter transporters: oligomerization as a determinant of transporter function and trafficking

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

Plasma membrane monoamine transporters: structure, regulation and function

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

The antidepressant-sensitive dopamine transporter in Drosophila melanogaster: a primordial carrier for catecholamines.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

Calcineurin interacts with the serotonin transporter C-terminus to modulate its plasma membrane expression and serotonin uptake

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5270474

PCR-ligation-PCR mutagenesis: a protocol for creating gene fusions and mutations

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27986813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M116.762872

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

27986813

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27986813%20AND%20SRC:MED&resulttype=core&format=json