Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma (Q38453759)

3 September 2017

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma (English)

1 reference

3 September 2017

Arjun A Rao

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Tathiane M Malta

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Pietro Zoppoli

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Jiguang Wang

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Ganiraju Manyam

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Matthew Meyerson

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Raul Rabadan

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Michele Ceccarelli

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Stefano M Pagnotta

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Olena Morozova

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David H Gutmann

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David Haussler

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3 September 2017

Tom Mikkelsen

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3 September 2017

Rameen Beroukhim

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3 September 2017

Carlos Gilberto Carlotti

object named as

Carlos Gilberto Carlotti

1 reference

3 September 2017

Andrew D Cherniack

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3 September 2017

Norman L Lehman

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Daniela Pretti da Cunha Tirapelli

3 September 2017

object named as

Daniela Pretti da Cunha Tirapelli

1 reference

3 September 2017

Sofie R Salama

1 reference

3 September 2017

Roel G W Verhaak

1 reference

3 September 2017

Floris P Barthel

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Antonio Iavarone

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Siyuan Zheng

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Jill S. Barnholtz-Sloan

object named as

Jill S Barnholtz-Sloan

0 references

Thais S Sabedot

1 reference

3 September 2017

Bradley A Murray

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3 September 2017

Yulia Newton

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3 September 2017

Amie Radenbaugh

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3 September 2017

Samreen Anjum

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3 September 2017

Shiyun Ling

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3 September 2017

Mia Grifford

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3 September 2017

Hailei Zhang

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3 September 2017

Laila Poisson

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3 September 2017

Arvind Rao

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3 September 2017

Ching C Lau

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3 September 2017

W K Alfred Yung

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3 September 2017

Jason Huse

1 reference

3 September 2017

Daniel J Brat

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3 September 2017

Kenneth Hess

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3 September 2017

Ganesh Rao

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3 September 2017

Lee Cooper

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3 September 2017

Rehan Akbani

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3 September 2017

Margaret Wrensch

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3 September 2017

Kenneth D Aldape

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3 September 2017

Peter W Laird

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3 September 2017

TCGA Research Network

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3 September 2017

Houtan Noushmehr

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3 September 2017

language of work or name

English

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publication date

1 January 2016

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3 September 2017

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3 September 2017

164

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3 September 2017

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3 September 2017

550-563

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DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors

3 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

The somatic genomic landscape of glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Inferring tumour purity and stromal and immune cell admixture from expression data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

The integrated landscape of driver genomic alterations in glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

TERT promoter mutations in familial and sporadic melanoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Sister chromatid cohesion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Mutational inactivation of STAG2 causes aneuploidy in human cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician's perspective

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

IDH1 and IDH2 mutations in gliomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

The 2007 WHO classification of tumours of the central nervous system

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Epidemiology and molecular pathology of glioma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

SOX2 functions to maintain neural progenitor identity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Mutational landscape and clonal architecture in grade II and III gliomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Degradation of AMPK by a cancer-specific ubiquitin ligase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Distribution and characterization of microglia/macrophages in human brain tumors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Codeletion of 1p and 19q determines distinct gene methylation and expression profiles in IDH-mutated oligodendroglial tumors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4754110

10.1016/J.CELL.2015.12.028

31 August 2018

Identifiers

DOI

1 reference

3 September 2017

1 reference

3 September 2017

PubMed publication ID

26824661

1 reference