Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma (Q34083282)

30 July 2017

title

Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma (English)

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30 July 2017

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Massimo Squatrito

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Markus Riester

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Franziska Michor

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30 July 2017

Eric C Holland

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30 July 2017

Tatsuya Ozawa

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30 July 2017

Yu-Kang Cheng

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30 July 2017

Jason T Huse

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30 July 2017

Karim Helmy

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30 July 2017

Nikki Charles

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30 July 2017

publication date

1 August 2014

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

288-300

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Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.

30 July 2017

cites work

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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

5 July 2018

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The definition of primary and secondary glioblastoma

5 July 2018

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Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice

5 July 2018

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Identification of global alteration of translational regulation in glioma in vivo

5 July 2018

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Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma

5 July 2018

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A mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis

5 July 2018

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Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression

5 July 2018

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Mosaic analysis with double markers reveals tumor cell of origin in glioma

5 July 2018

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Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells.

5 July 2018

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Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas

5 July 2018

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PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

5 July 2018

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A mathematical framework to determine the temporal sequence of somatic genetic events in cancer

5 July 2018

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A differentiation-based phylogeny of cancer subtypes

5 July 2018

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

5 July 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

5 July 2018

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The transcriptional network for mesenchymal transformation of brain tumours.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations

5 July 2018

1 reference

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The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Modeling Adult Gliomas Using RCAS/t-va Technology

5 July 2018

1 reference

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Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis

5 July 2018

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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

5 July 2018

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

5 July 2018

1 reference

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Role of platelet-derived growth factors in physiology and medicine

5 July 2018

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5 July 2018

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Pten haploinsufficiency accelerates formation of high-grade astrocytomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

5 July 2018

1 reference

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Chronic myeloid leukaemia

5 July 2018

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The 2007 WHO classification of tumours of the central nervous system

5 July 2018

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Aneuploidy and confined chromosomal mosaicism in the developing human brain.

5 July 2018

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Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma

5 July 2018

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Visualization of interphase chromosomes in postmitotic cells of the human brain by multicolour banding (MCB).

5 July 2018

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

5 July 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

5 July 2018

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Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

5 July 2018

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mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma

5 July 2018

1 reference

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Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model

5 July 2018

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Mechanism of action and in vivo role of platelet-derived growth factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Genetic instabilities in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

The neighbor-joining method: a new method for reconstructing phylogenetic trees

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: differential expression and pathological meaning

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

PTEN methylation and expression in glioblastomas

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

Generation of RCAS vectors useful for functional genomic analyses.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4143139

10.1016/J.CCR.2014.06.005

28 October 2018

Identifiers

DOI

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30 July 2017

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30 July 2017

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