Dopamine and Huntington's disease. (Q38379277)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

review article

1 reference

title

Dopamine and Huntington's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

Erratum. Correction to: Dopamine and Huntington's disease

3 March 2020

main subject

Huntington's disease

0 references

corrigendum / erratum

1 reference

10.1586/14737175.2015.1088179

DOI

12 July 2019

http://api.crossref.org/works?select=update-to&filter=doi:10.1586/14737175.2015.1088179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Laetitia C Schwab

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Shady N Garas

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Janelle Drouin-Ouellet

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Sarah L Mason

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

language of work or name

1 reference

16 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

3 March 2020

published in

1 reference

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3 March 2020

volume

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3 March 2020

issue

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3 March 2020

page(s)

445-458

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25773746%20AND%20SRC:MED&resulttype=core&format=json

Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records

3 March 2020

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

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Huntington disease: natural history, biomarkers and prospects for therapeutics

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Mechanisms of neurodegeneration in Huntington's disease.

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Mutant huntingtin is present in neuronal grafts in Huntington disease patients

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Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the Huntington's disease mutation

21 January 2018

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Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

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Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

21 January 2018

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A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

21 January 2018

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Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

21 January 2018

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Impaired dopamine release and uptake in R6/1 Huntington's disease model mice

21 January 2018

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Motor function and dopamine release measurements in transgenic Huntington's disease model rats

21 January 2018

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Predictive test for Huntington's chorea

21 January 2018

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Chemical pathology of Huntington's disease

21 January 2018

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Neurochemical alterations in Huntington's chorea: a study of post-mortem brain tissue

21 January 2018

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Corticostriatal circuit dysfunction in Huntington's disease: intersection of glutamate, dopamine and calcium

21 January 2018

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The neurobiology of dopamine signaling

21 January 2018

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Human brain D1 and D2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases

21 January 2018

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Parkinson's disease. First of two parts

21 January 2018

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Structure and function of dopamine receptors

21 January 2018

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Role of dopamine D2 receptors in human reinforcement learning

21 January 2018

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Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits

21 January 2018

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Mesocortical dopamine modulation of executive functions: beyond working memory

21 January 2018

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The neural circuitry of executive functions in healthy subjects and Parkinson's disease

21 January 2018

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Chemistry of the mind: neurochemical modulation of prefrontal cortical function

21 January 2018

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The physiology, signaling, and pharmacology of dopamine receptors

21 January 2018

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The basal ganglia: focused selection and inhibition of competing motor programs

21 January 2018

1 reference

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D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

The functional anatomy of basal ganglia disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Dopamine release is severely compromised in the R6/2 mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

21 January 2018

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Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea

21 January 2018

1 reference

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A quantitative investigation of the substantia nigra in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Serotonin and dopamine striatal innervation in Parkinson's disease and Huntington's chorea

21 January 2018

1 reference

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Tyrosine hydroxylase-like immunoreactivity is distributed in the matrix compartment of normal human and Huntington's disease striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Decreased striatal monoaminergic terminals in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers

21 January 2018

1 reference

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Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons.

21 January 2018

1 reference

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Bimodal induction of dopamine-mediated striatal neurotoxicity is mediated through both activation of D1 dopamine receptors and autoxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.

21 January 2018

1 reference

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Dopaminergic signaling and striatal neurodegeneration in Huntington's disease

21 January 2018

1 reference

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PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease

21 January 2018

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Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers

21 January 2018

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Changes in striatal dopamine D2 receptor binding in pre-clinical Huntington's disease

21 January 2018

1 reference

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Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

21 January 2018

1 reference

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Striatal D1 and D2 receptor binding in patients with Huntington's disease and other choreas A PET study

21 January 2018

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Huntington's disease progression. PET and clinical observations.

21 January 2018

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Detection of Huntington's disease decades before diagnosis: the Predict-HD study

21 January 2018

1 reference

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The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease

21 January 2018

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Hypothalamic involvement in Huntington's disease: an in vivo PET study

21 January 2018

1 reference

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Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Extrastriatal dopamine D(2) receptor binding in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

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Animal models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

21 January 2018

1 reference

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Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice

21 January 2018

1 reference

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Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice

21 January 2018

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Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

21 January 2018

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

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Huntington's Disease: Can Mice Lead the Way to Treatment?

21 January 2018

1 reference

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Increased Cerebrospinal Fluid Dopamine and 3,4‐Dihydroxyphenylacetic Acid Levels in Huntington's Disease: Evidence for an Overactive Dopaminergic Brain Transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

In vivo Dopamine Efflux is Decreased in Striatum of both Fragment (R6/2) and Full-Length (YAC128) Transgenic Mouse Models of Huntington's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease

21 January 2018

1 reference

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Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease.

21 January 2018

1 reference

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Tetrabenazine for the treatment of hyperkinetic movement disorders: a review of the literature.

21 January 2018

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Neurochemical changes following the administration of depleters of biogenic monoamines

21 January 2018

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Depletion of monoamine transmitters by tetrabenazine in brain tissue in Huntington's disease

21 January 2018

1 reference

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Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter

21 January 2018

1 reference

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Tetrabenazine therapy of dystonia, chorea, tics, and other dyskinesias

21 January 2018

1 reference

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Long-term effects of tetrabenazine in hyperkinetic movement disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Tetrabenazine treatment for Huntington's disease-associated chorea

21 January 2018

1 reference

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Short-term effects of tetrabenazine on chorea associated with Huntington's disease

21 January 2018

1 reference

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The long-term effect of tetrabenazine in the management of Huntington disease

21 January 2018

1 reference

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Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

A study of chorea after tetrabenazine withdrawal in patients with Huntington disease

21 January 2018

1 reference

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The gait abnormality of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Effect of neuroleptic treatment on involuntary movements and motor performances in Huntington's disease

21 January 2018

1 reference

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Drug treatment in 117 cases of Huntington's disease with special reference to fluphenazine (Prolixin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia

21 January 2018

1 reference

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A Europe-wide assessment of current medication choices in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Olanzapine in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Olanzapine for Huntington's disease: an open label study

21 January 2018

1 reference

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A comparative trial use of sulpiride and risperidone in Huntington's disease: a pilot study.

21 January 2018

1 reference

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Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.

21 January 2018

1 reference

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Treatment of the symptoms of Huntington's disease: preliminary results comparing aripiprazole and tetrabenazine

21 January 2018

1 reference

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Bromocriptine, an ergot alkaloid, inhibits excitatory amino acid release mediated by glutamate transporter reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Effects of bromocriptine on central dopaminergic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Bromocriptine in Huntington Chorea

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Acute treatment of Huntington's chorea with lisuride

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Levodopa and Huntington's chorea

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Letter: Huntington's chorea and levodopa

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Levodopa in Huntington's chorea

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Emerging drug therapies in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Late onset levodopa responsive Huntington's disease with minimal chorea masquerading as Parkinson plus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

In vivo pharmacology of the dopaminergic stabilizer pridopidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for mot

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Schizophrenia: from dopamine to glutamate and back

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Efficacy and safety of the dopaminergic stabilizer Pridopidine (ACR16) in patients with Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Pridopidine for the treatment of motor function in patients with Huntington's disease (MermaiHD): a phase 3, randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

A randomized, double-blind, placebo-controlled trial of pridopidine in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Prefrontal dopamine signaling and cognitive symptoms of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

A convergent model for cognitive dysfunctions in Parkinson's disease: the critical dopamine-acetylcholine synaptic balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Clinical neurogenetics: huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

High-dose olanzapine in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383

How dopamine dysregulation leads to psychotic symptoms? Abnormal mesolimbic and mesostriatal prediction error signalling in psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.2015.1025383