Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II. (Q43206399)

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scientific article published on 11 February 2008

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English	Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.	scientific article published on 11 February 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

16 November 2017

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II. (English)

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

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Emmanuel Brouillet

11

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16 November 2017

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Nicole Déglon

10

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Philippe Hantraye

9

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Philippe Hantraye

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16 November 2017

Yaël Trioulier

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Yaël Trioulier

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16 November 2017

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Elsa Diguet

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16 November 2017

4

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Carole Malgorn

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16 November 2017

Marie-Claude Gaillard

5

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Marie-Claude Gaillard

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16 November 2017

Jean-Marc Elalouf

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Jean-Marc Elalouf

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16 November 2017

8

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Stan Krajewski

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Europe PubMed Central

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16 November 2017

author name string

Alexandra Benchoua

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Europe PubMed Central

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16 November 2017

Noelle Dufour

6

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16 November 2017

publication date

11 February 2008

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16 November 2017

Human Molecular Genetics

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16 November 2017

17

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Europe PubMed Central

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16 November 2017

10

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Europe PubMed Central

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16 November 2017

1446-1456

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Europe PubMed Central

PMC publication ID

16 November 2017

Dopaminergic signaling and striatal neurodegeneration in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

Normal huntingtin function: an alternative approach to Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation

1 reference

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25 May 2018

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

1 reference

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25 May 2018

Ca2+ regulation and gene expression in normal brain aging

1 reference

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25 May 2018

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

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25 May 2018

Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons.

1 reference

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25 May 2018

Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases

1 reference

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25 May 2018

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

1 reference

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25 May 2018

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

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25 May 2018

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

1 reference

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25 May 2018

Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.

1 reference

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25 May 2018

Neuronal cell death in Huntington's disease: a potential role for dopamine

1 reference

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25 May 2018

Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice

1 reference

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25 May 2018

Wild-type huntingtin protects from apoptosis upstream of caspase-3.

1 reference

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25 May 2018

Mitochondrial control of cell death

1 reference

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25 May 2018

Replicating Huntington's disease phenotype in experimental animals

1 reference

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25 May 2018

Dopamine receptors: from structure to function

2 references

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25 May 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

https://api.crossref.org/works/10.1093%2FHMG%2FDDN033

21 January 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

25 May 2018

Assay of succinate dehydrogenase activity by a colorimetric-continuous method using iodonitrotetrazolium chloride as electron acceptor.

1 reference

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25 May 2018

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

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25 May 2018

Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.

1 reference

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15 August 2018

Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Dopamine induces a PI3-kinase-independent activation of Akt in striatal neurons: a new route to cAMP response element-binding protein phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

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1 reference

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15 August 2018

Dopamine modulates the susceptibility of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor

1 reference

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15 August 2018

Parenterally administered 3-nitropropionic acid and amphetamine can combine to produce damage to terminals and cell bodies in the striatum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Mitochondrial defect in Huntington's disease caudate nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2367694

15 August 2018

Pre- and postsynaptic neurotoxic effects of dopamine demonstrated by intrastriatal injection

1 reference

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15 August 2018

Morphologic and histochemical characteristics of a spared subset of striatal neurons in Huntington's disease

1 reference

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Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN033

21 January 2018

Mechanisms of dopamine-induced cell death in cultured rat forebrain neurons: interactions with and differences from glutamate-induced cell death

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https://pubmed.ncbi.nlm.nih.gov/18267960

12 December 2020

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Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

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https://pubmed.ncbi.nlm.nih.gov/18267960

12 December 2020

based on heuristic

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Identifiers

10.1093/HMG/DDN033

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

ResearchGate publication ID

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