Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models (Q38375945)

2 September 2017

1 reference

title

Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models (English)

1 reference

2 September 2017

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Desiree Abdurrachim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Joost J F P Luiken

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jan F C Glatz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

12 March 2015

1 reference

2 September 2017

published in

Cardiovascular Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

106

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6 June 2020

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

194-205

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

Dyssynchrony of Ca2+ release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction.

6 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Myocardial fatty acid metabolism in health and disease

21 January 2018

1 reference

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Mitochondrial fatty acid oxidation alterations in heart failure, ischaemic heart disease and diabetic cardiomyopathy

21 January 2018

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Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes.

21 January 2018

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Differential translocation of the fatty acid transporter, FAT/CD36, and the glucose transporter, GLUT4, coordinates changes in cardiac substrate metabolism during ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

High rates of residual fatty acid oxidation during mild ischemia decrease cardiac work and efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Quantitative PET imaging detects early metabolic remodeling in a mouse model of pressure-overload left ventricular hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Carnitine palmitoyltransferase-1b deficiency aggravates pressure overload-induced cardiac hypertrophy caused by lipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiomyocyte triglyceride accumulation and reduced ventricular function in mice with obesity reflect increased long chain Fatty Acid uptake and de novo Fatty Acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

High fat feeding in mice is insufficient to induce cardiac dysfunction and does not exacerbate heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Gender-dependent effects of high-fat lard diet on cardiac function in C57Bl/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

The role of dietary fatty acids in predicting myocardial structure in fat-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Dietary fat and heart failure: moving from lipotoxicity to lipoprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Rescue of heart lipoprotein lipase-knockout mice confirms a role for triglyceride in optimal heart metabolism and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

A novel mouse model of lipotoxic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Absence of fatty acid transporter CD36 protects against Western-type diet-related cardiac dysfunction following pressure overload in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Myocardial recovery from ischemia is impaired in CD36-null mice and restored by myocyte CD36 expression or medium-chain fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

A murine model of isolated cardiac steatosis leads to cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Prolonged QT interval and lipid alterations beyond β-oxidation in very long-chain acyl-CoA dehydrogenase null mouse hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Development and pathomechanisms of cardiomyopathy in very long-chain acyl-CoA dehydrogenase deficient (VLCAD(-/-)) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac-specific VLCAD deficiency induces dilated cardiomyopathy and cold intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Tissue-specific strategies of the very-long chain acyl-CoA dehydrogenase-deficient (VLCAD-/-) mouse to compensate a defective fatty acid β-oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Myocardial energy shortage and unmet anaplerotic needs in the fasted long-chain acyl-CoA dehydrogenase knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Fasting-induced myocardial lipid accumulation in long-chain acyl-CoA dehydrogenase knockout mice is accompanied by impaired left ventricular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiomyocyte specific peroxisome proliferator-activated receptor-α overexpression leads to irreversible damage in ischemic murine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Mitochondrial long chain fatty acid beta-oxidation in man and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Homozygous carnitine palmitoyltransferase 1a (liver isoform) deficiency is lethal in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Inhibition of carnitine palymitoyltransferase1b induces cardiac hypertrophy and mortality in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Sarcolemmal fatty acid uptake vs. mitochondrial beta-oxidation as target to regress cardiac insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Multiphasic triacylglycerol dynamics in the intact heart during acute in vivo overexpression of CD36

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Myocardial triacylglycerol metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Lipid metabolism and toxicity in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Lipotoxicity in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Congestive heart failure with preserved ejection fraction is associated with severely impaired dynamic Starling mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac fatty acid uptake and transport in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Myocardial infarction and heart failure in the db/db diabetic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Metabolic manipulation in ischaemic heart disease, a novel approach to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Defects of mitochondrial beta-oxidation: a growing group of disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

MicroRNAs in lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

MicroRNAs in metabolism and metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Regulatory RNAs and paracrine networks in the heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Acute lipoprotein lipase deletion in adult mice leads to dyslipidemia and cardiac dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

Polymorphic ventricular tachycardia and abnormal Ca2+ handling in very-long-chain acyl-CoA dehydrogenase null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVV105

21 January 2018

Identifiers

DOI

10.1093/CVR/CVV105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json

release_tyogea44lzh2vffltth4rlxxgi

6 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tyogea44lzh2vffltth4rlxxgi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25765936%20AND%20SRC:MED&resulttype=core&format=json