A global transcription cofactor bound to juxtaposed strands of unwound DNA. (Q38316757)

2 September 2017

title

A global transcription cofactor bound to juxtaposed strands of unwound DNA. (English)

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SUB1 regulator of transcription

2 September 2017

main subject

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identical protein binding

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Sebastiaan Werten

series ordinal

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2 September 2017

Dino Moras

series ordinal

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2 September 2017

publication date

15 January 2006

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Nature Structural & Molecular Biology

2 September 2017

published in

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2 September 2017

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2 September 2017

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2 September 2017

page(s)

181-182

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Transcriptional coactivator PC4 stimulates promoter escape and facilitates transcriptional synergy by GAL4-VP16

2 September 2017

cites work

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High-affinity DNA binding by the C-terminal domain of the transcriptional coactivator PC4 requires simultaneous interaction with two opposing unpaired strands and results in helix destabilization.

21 January 2018

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C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site

21 January 2018

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Identification of the single-stranded DNA binding surface of the transcriptional coactivator PC4 by NMR.

21 January 2018

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Interaction of PC4 with melted DNA inhibits transcription

21 January 2018

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The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage

21 January 2018

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The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription.

21 January 2018

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Multimerization of the adenovirus DNA-binding protein is the driving force for ATP-independent DNA unwinding during strand displacement synthesis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NSMB1044

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Dimensions Publication ID

2 September 2017

1005721717

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