Bioartificial livers in vitro and in vivo: tailoring biocomponents to the expanding variety of applications (Q38264625)

1 September 2017

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title

Bioartificial livers in vitro and in vivo: tailoring biocomponents to the expanding variety of applications (English)

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1 September 2017

Jurgen Seppen

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Martien van Wenum

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1 September 2017

Robert Afm Chamuleau

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1 September 2017

Thomas M van Gulik

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1 September 2017

Adriaan Siliakus

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1 September 2017

Ruurdtje Hoekstra

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1 September 2017

language of work or name

English

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publication date

4 November 2014

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Expert Opinion on Biological Therapy

1 September 2017

published in

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1 September 2017

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1 September 2017

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1 September 2017

page(s)

1745-1760

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

1 September 2017

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Increased hepatic functionality of the human hepatoma cell line HepaRG cultured in the AMC bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Evaluation of encapsulated liver cell spheroids in a fluidised-bed bioartificial liver for treatment of ischaemic acute liver failure in pigs in a translational setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Spheroid-based three-dimensional liver-on-a-chip to investigate hepatocyte-hepatic stellate cell interactions and flow effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Workshop meeting report Organs-on-Chips: human disease models

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Liver Cell Culture Devices

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Proliferative human cell sources applied as biocomponent in bioartificial livers: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Bioartificial liver systems: current status and future perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Clinical monitoring of intracranial pressure in fulminant hepatic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Lessons from look-back in acute liver failure? A single centre experience of 3300 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Perspectives on liver failure: past and future

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

The systemic inflammatory response syndrome in acute liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Auxiliary partial orthotopic versus standard orthotopic whole liver transplantation for acute liver failure: a reappraisal from a single center by a case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Which hepatocyte will it be? Hepatocyte choice for bioartificial liver support systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Loss and Recovery of Liver Regeneration in Rats with Fulminant Hepatic Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

In vitro evaluation of a novel bioreactor based on an integral oxygenator and a spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Bioengineering the liver: scale-up and cool chain delivery of the liver cell biomass for clinical targeting in a bioartificial liver support system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Liver-assist device with a microfluidics-based vascular bed in an animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Current concepts of mechanisms in drug-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Plasmodium vivax: modern strategies to study a persistent parasite's life cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Cellular models for the screening and development of anti-hepatitis C virus agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Malaria eradication back on the table

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

In vitro zonation and toxicity in a hepatocyte bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Perfused multiwell plate for 3D liver tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Rapid, large-scale formation of porcine hepatocyte spheroids in a novel spheroid reservoir bioartificial liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Acetaminophen-induced hepatotoxicity of gel entrapped rat hepatocytes in hollow fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Artificial and bioartificial liver devices: present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

In vitro analysis of a hepatic device with intrinsic microvascular-based channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

A microfluidic hepatic coculture platform for cell-based drug metabolism studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Comparative Analysis of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cells Reveals Current Drawbacks and Possible Strategies for Improved Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Genomics and proteomics analysis of cultured primary rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Temporal gene expression analysis of monolayer cultured rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Generation of proliferating human hepatocytes using Upcyte® technology: characterisation and applications in induction and cytotoxicity assays

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Chapter 4 Preparation of Isolated Rat Liver Cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Drug interaction studies: study design, data analysis, and implications for dosing and labeling

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

General review on in vitro hepatocyte models and their applications

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Which are the right cells to be used in a bioartificial liver?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Cells for bioartificial liver devices: the human hepatoma-derived cell line C3A produces urea but does not detoxify ammonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Stem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Biochemical and molecular characterization of hepatocyte-like cells derived from human bone marrow mesenchymal stem cells on a novel three-dimensional biocompatible nanofibrous scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Use of a rotary bioartificial liver in the differentiation of human liver stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

What is the point of large-scale collections of human induced pluripotent stem cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Pluripotent stem cell-derived hepatocyte-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Modeling hepatitis C virus infection using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

The promotion of hepatic maturation of human pluripotent stem cells in 3D co-culture using type I collagen and Swiss 3T3 cell sheets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Vascularized and functional human liver from an iPSC-derived organ bud transplant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Production of hepatocyte-like cells from human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Mouse liver repopulation with hepatocytes generated from human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Direct reprogramming of human fibroblasts to functional and expandable hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Human hepatocytes with drug metabolic function induced from fibroblasts by lineage reprogramming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Reconstruction of liver organoid using a bioreactor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Interleukin-1 receptor antagonist modulates the early phase of liver regeneration after partial hepatectomy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Cytokine adsorbing columns

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Kinetic analysis of the human blood-brain barrier transport of lactate and its influence by hypercapnia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Increased brain lactate is central to the development of brain edema in rats with chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Cerebral microdialysis in patients with fulminant hepatic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Brain lactate uptake increases at the site of impact after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Lactate: a preferred fuel for human brain metabolism in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Brain lactate in hepatic encephalopathy: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Oxidation of albumin is enhanced in the presence of uremic toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Human serum albumin, systemic inflammation, and cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Apolipoprotein A-I Modulates Regulatory T Cells in Autoimmune LDLr−/−, ApoA-I−/− Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

The significant improvement of survival times and pathological parameters by bioartificial liver with recombinant HepG2 in porcine liver failure model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Cytochrome p450 and chemical toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Intact signaling by transforming growth factor beta is not required for termination of liver regeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Bioartificial liver treatment in rats with fulminant hepatic failure: effect on DNA-binding activity of liver-enriched and growth-associated transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and a dynamic three-dimensional bioreactor system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2014.950651

10.1517/14712598.2014.950651

21 January 2018

Identifiers

DOI

1 reference

1 September 2017

1 reference