Epithelial function and dysfunction in asthma. (Q38198788)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Epithelial function and dysfunction in asthma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

D E Davies

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

publication date

1 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

Clinical & Experimental Allergy

12 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

1299-1313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

Asthma: clinical expression and molecular mechanisms

12 March 2020

cites work

1 reference

Global asthma prevalence in adults: findings from the cross-sectional world health survey

21 January 2018

1 reference

Factors accounting for asthma variability: achieving optimal symptom control for individual patients.

21 January 2018

1 reference

A new perspective on concepts of asthma severity and control.

21 January 2018

1 reference

From phenotypes to endotypes to asthma treatment

21 January 2018

1 reference

Asthma: defining of the persistent adult phenotypes

21 January 2018

1 reference

Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome

21 January 2018

1 reference

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

21 January 2018

1 reference

Cluster analysis and clinical asthma phenotypes.

21 January 2018

1 reference

Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

21 January 2018

1 reference

Non-eosinophilic cor ticosteroid unresponsive asthma

21 January 2018

1 reference

A new look at the pathogenesis of asthma

21 January 2018

1 reference

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

21 January 2018

1 reference

Mold sensitization is common amongst patients with severe asthma requiring multiple hospital admissions

21 January 2018

1 reference

The link between fungi and severe asthma: a summary of the evidence.

21 January 2018

1 reference

Ambient pollen concentrations and emergency department visits for asthma and wheeze

21 January 2018

1 reference

A novel group of rhinoviruses is associated with asthma hospitalizations

21 January 2018

1 reference

Mechanisms of virus-induced asthma exacerbations: state-of-the-art. A GA2LEN and InterAirways document.

21 January 2018

1 reference

The September epidemic of asthma exacerbations in children: a search for etiology

21 January 2018

1 reference

Particulate air pollutants and asthma: a paradigm for the role of oxidative stress in PM-induced adverse health effects

21 January 2018

1 reference

Occupational asthma: current concepts in pathogenesis, diagnosis, and management

21 January 2018

1 reference

The mechanism of exercise-induced asthma is ...

21 January 2018

1 reference

Asthma and obesity: a known association but unknown mechanism

21 January 2018

1 reference

Cluster analysis of obesity and asthma phenotypes

21 January 2018

1 reference

21 January 2018

1 reference

Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma

21 January 2018

1 reference

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

21 January 2018

1 reference

A large-scale, consortium-based genomewide association study of asthma

21 January 2018

1 reference

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

21 January 2018

1 reference

The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma.

21 January 2018

1 reference

Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness

21 January 2018

1 reference

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

21 January 2018

1 reference

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

21 January 2018

1 reference

Filaggrin mutations, atopic eczema, hay fever, and asthma in children

21 January 2018

1 reference

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

21 January 2018

1 reference

Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma.

21 January 2018

1 reference

Genetic and environmental influence on asthma: a population-based study of 11,688 Danish twin pairs.

21 January 2018

1 reference

Gene-environment interactions in human disease: nuisance or opportunity?

21 January 2018

1 reference

The airway epithelium is central to the pathogenesis of asthma

21 January 2018

1 reference

The airway epithelium in asthma

21 January 2018

1 reference

The sentinel role of the airway epithelium in asthma pathogenesis

21 January 2018

1 reference

The airway epithelium: structural and functional properties in health and disease

21 January 2018

1 reference

Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge--an ex vivo and in silico approach.

21 January 2018

1 reference

Mucociliary clearance--a critical upper airway host defense mechanism and methods of assessment.

21 January 2018

1 reference

21 January 2018

The airway goblet cell

1 reference

Clara cell: progenitor for the bronchiolar epithelium

21 January 2018

1 reference

Basal cells as stem cells of the mouse trachea and human airway epithelium

21 January 2018

1 reference

Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium

21 January 2018

1 reference

CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells

21 January 2018

1 reference

Development of a repeated exposure protocol of human bronchial epithelium in vitro to study the long-term effects of atmospheric particles

21 January 2018

1 reference

Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

21 January 2018

1 reference

Tight junctions and human diseases

21 January 2018

1 reference

Occludin: a novel integral membrane protein localizing at tight junctions

21 January 2018

1 reference

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

21 January 2018

1 reference

Structure and function of claudins.

21 January 2018

1 reference

Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions

21 January 2018

1 reference

The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

21 January 2018

1 reference

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia

21 January 2018

1 reference

Dynamics and functions of tight junctions

21 January 2018

1 reference

Claudins and epithelial paracellular transport

21 January 2018

1 reference

Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins

21 January 2018

1 reference

Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells

21 January 2018

1 reference

Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

21 January 2018

1 reference

Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability

21 January 2018

1 reference

Composition and formation of intercellular junctions in epithelial cells

21 January 2018

1 reference

Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling

21 January 2018

1 reference

Defective epithelial barrier function in asthma.

21 January 2018

1 reference

TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation

21 January 2018

1 reference

Shotgun proteomic analysis of human-induced sputum

21 January 2018

1 reference

Airway mucus: From production to secretion.

21 January 2018

1 reference

Barrier properties of mucus

21 January 2018

1 reference

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

21 January 2018

1 reference

Transport of metal oxide nanoparticles and single-walled carbon nanotubes in human mucus

21 January 2018

1 reference

Structure and function of the polymeric mucins in airways mucus.

21 January 2018

1 reference

Mucus hypersecretion in asthma: causes and effects

21 January 2018

1 reference

Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B.

21 January 2018

1 reference

Regulation of mucin genes in chronic inflammatory airway diseases

21 January 2018

1 reference

Respiratory tract mucin genes and mucin glycoproteins in health and disease

21 January 2018

1 reference

SPDEF regulates goblet cell hyperplasia in the airway epithelium

21 January 2018

1 reference

Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells

21 January 2018

1 reference

Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-kappaB paradigm

21 January 2018

1 reference

Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells

21 January 2018

1 reference

Innate immunity in the respiratory epithelium.

21 January 2018

1 reference

Oxidant and antioxidant balance in the airways and airway diseases

21 January 2018

1 reference

Oxidative stress: its role in air pollution and adverse health effects

21 January 2018

1 reference

Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2

21 January 2018

1 reference

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

Toll-like receptor signalling

21 January 2018

1 reference

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

Structure, function and pathophysiology of protease activated receptors.

21 January 2018

1 reference

How C-type lectins detect pathogens

21 January 2018

1 reference

DAMPs, PAMPs and alarmins: all we need to know about danger

21 January 2018

1 reference

How dying cells alert the immune system to danger

21 January 2018

1 reference

The danger within: endogenous danger signals, atopy and asthma

21 January 2018

1 reference

Disease-associated functions of IL-33: the new kid in the IL-1 family

21 January 2018

1 reference

The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses

21 January 2018

1 reference

Characterization of airway plugging in fatal asthma.

21 January 2018

1 reference

Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma

21 January 2018

1 reference

Epithelial stress and structural remodelling in childhood asthma

21 January 2018

1 reference

Epithelial cells and airway diseases

21 January 2018

1 reference

Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis

21 January 2018

1 reference

Barrier disrupting effects of alternaria alternata extract on bronchial epithelium from asthmatic donors

21 January 2018

1 reference

Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution

21 January 2018

1 reference

Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

21 January 2018

1 reference

The airway epithelium in asthma: developmental issues that scar the airways for life?

21 January 2018

1 reference

The role of the epithelium in airway remodeling in asthma.

21 January 2018

1 reference

The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke

21 January 2018

1 reference

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

21 January 2018

1 reference

Fine particulate matter from urban ambient and wildfire sources from California's San Joaquin Valley initiate differential inflammatory, oxidative stress, and xenobiotic responses in human bronchial epithelial cells

21 January 2018

1 reference

Diesel exhaust enhances influenza virus infections in respiratory epithelial cells

21 January 2018

1 reference

Respiratory syncytial virus induces oxidative stress by modulating antioxidant enzymes

21 January 2018

1 reference

Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells.

21 January 2018

1 reference

Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities

21 January 2018

1 reference

Glutathione S-transferase polymorphisms, asthma susceptibility and confounding variables: a meta-analysis

21 January 2018

1 reference

Glutathione-S-transferase M1 regulation of diesel exhaust particle-induced pro-inflammatory mediator expression in normal human bronchial epithelial cells

21 January 2018

1 reference

Role of the Nrf2-mediated signaling pathway as a negative regulator of inflammation: implications for the impact of particulate pollutants on asthma

21 January 2018

1 reference

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress

21 January 2018

1 reference

Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration

21 January 2018

1 reference

The unfolded protein response: from stress pathway to homeostatic regulation

21 January 2018

1 reference

ER stress-induced inflammation: does it aid or impede disease progression?

21 January 2018

1 reference

Endoplasmic reticulum stress as a pro-fibrotic stimulus

21 January 2018

1 reference

Protein misfolding and endoplasmic reticulum stress in chronic lung disease.

21 January 2018

1 reference

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6

21 January 2018

1 reference

PGE2 maintains the tone of the guinea pig trachea through a balance between activation of contractile EP1 receptors and relaxant EP2 receptors

21 January 2018

1 reference

Reversal of myofibroblast differentiation by prostaglandin E(2).

21 January 2018

1 reference

Role of PGE2 in asthma and nonasthmatic eosinophilic bronchitis

21 January 2018

1 reference

Lipoxin and aspirin-triggered lipoxins.

21 January 2018

1 reference

Resolvin D1 and Resolvin E1 Promote the Resolution of Allergic Airway Inflammation via Shared and Distinct Molecular Counter-Regulatory Pathways

21 January 2018

1 reference

Uncontrolled airway inflammation in lung disease represents a defect in counter-regulatory signaling

21 January 2018

1 reference

Epithelial regulation of eicosanoid production in asthma

21 January 2018

1 reference

An update on the role of leukotrienes in asthma

21 January 2018

1 reference

Transglutaminase 2, a novel regulator of eicosanoid production in asthma revealed by genome-wide expression profiling of distinct asthma phenotypes

21 January 2018

1 reference

Eosinophil cysteinyl leukotriene synthesis mediated by exogenous secreted phospholipase A2 group X.

21 January 2018

1 reference

Dynamic role of epithelium-derived cytokines in asthma

21 January 2018

1 reference

IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies

21 January 2018

1 reference

Targeting interleukin-4 in asthma: lost in translation?

21 January 2018

1 reference

Breakdown in epithelial barrier function in patients with asthma: identification of novel therapeutic approaches.

21 January 2018

1 reference

Barrier responses of human bronchial epithelial cells to grass pollen exposure.

21 January 2018

1 reference

Epithelial eotaxin-2 and eotaxin-3 expression: relation to asthma severity, luminal eosinophilia and age at onset

21 January 2018

1 reference

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma

21 January 2018

1 reference

Asthmatic airway epithelium is intrinsically inflammatory and mitotically dyssynchronous

21 January 2018

1 reference

Epigenetic mechanisms and the development of asthma

21 January 2018

1 reference

Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells.

21 January 2018

1 reference

Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma

21 January 2018

1 reference

Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.

21 January 2018

1 reference

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma

21 January 2018

1 reference

In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects

21 January 2018

1 reference

Interferon-stimulated genes and their antiviral effector functions

21 January 2018

1 reference

Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study

21 January 2018

1 reference

Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens

21 January 2018

1 reference

Rhinoviruses, allergic inflammation, and asthma

21 January 2018

1 reference

Role of transforming growth factor-β in airway remodeling in asthma

21 January 2018

1 reference

Airway epithelial cells from asthmatic children differentially express proremodeling factors

21 January 2018

1 reference

The contribution of transforming growth factor-beta and epidermal growth factor signalling to airway remodelling in chronic asthma

21 January 2018

1 reference

TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids.

21 January 2018

1 reference

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response

21 January 2018

1 reference

Rhinovirus-induced basic fibroblast growth factor release mediates airway remodeling features.

21 January 2018

1 reference

Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling

21 January 2018

1 reference

Vascular endothelial growth factor as a key inducer of angiogenesis in the asthmatic airways

21 January 2018

1 reference

Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases.

21 January 2018

1 reference

The regulation of fibrosis in airway remodeling in asthma

21 January 2018

1 reference

Series "matrix metalloproteinases in lung health and disease": Biological role of matrix metalloproteinases: a critical balance

21 January 2018

1 reference

Human rhinovirus infection up-regulates MMP-9 production in airway epithelial cells via NF-{kappa}B.

21 January 2018

1 reference

Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma

21 January 2018

1 reference

Beta-adrenoceptor agonists and asthma--100 years of development

21 January 2018

1 reference

Efficacy of inhaled corticosteroids in asthma

21 January 2018

1 reference

The effect of treatment with omalizumab, an anti-IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma

21 January 2018

1 reference

Trials and tribulations in identifying new biologic treatments for asthma

21 January 2018

1 reference

21 January 2018

Animal models of asthma

1 reference

21 January 2018

Animal models of asthma.

1 reference

In vitro and ex vivo models of human asthma.

21 January 2018

1 reference

Diet and asthma: nutrition implications from prevention to treatment

21 January 2018

1 reference

Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathway

21 January 2018

1 reference

Exacerbation of tobacco smoke mediated apoptosis by resveratrol: an unexpected consequence of its antioxidant action

21 January 2018

1 reference

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

21 January 2018

1 reference

5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).

21 January 2018

1 reference

COX inhibitors for airway inflammation

21 January 2018

1 reference

PGE(2) receptor (EP(4)) agonists: potent dilators of human bronchi and future asthma therapy?

21 January 2018

1 reference

LXA4 stimulates ZO-1 expression and transepithelial electrical resistance in human airway epithelial (16HBE14o-) cells

21 January 2018

1 reference

Lebrikizumab treatment in adults with asthma

21 January 2018

1 reference

IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor α antagonist

21 January 2018

1 reference

Dupilumab in persistent asthma with elevated eosinophil levels

21 January 2018

1 reference

Efficacy of anti-interleukin-5 therapy with mepolizumab in patients with asthma: a meta-analysis of randomized placebo-controlled trials

21 January 2018

1 reference

Keratinocyte growth factor enhances barrier function without altering claudin expression in primary alveolar epithelial cells

21 January 2018

1 reference

Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus.

21 January 2018

1 reference

The Brussels Declaration: the need for change in asthma management

21 January 2018

1 reference

British Guideline on the Management of Asthma

21 January 2018

1 reference

Influence of outdoor aeroallergens on hospitalization for asthma in Canada

21 January 2018

1 reference

Exploring the obesity-asthma link: do all types of adiposity increase the risk of asthma?

21 January 2018

1 reference

Filaggrin variants confer susceptibility to asthma

21 January 2018

1 reference

Gene-environment interactions in asthma

21 January 2018

1 reference

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

21 January 2018

1 reference

Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma

21 January 2018

1 reference

Role of deficient type III interferon-λ production in asthma exacerbations

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CEA.12309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24661647%20AND%20SRC:MED&resulttype=core&format=json