Na/K pump regulation of cardiac repolarization: insights from a systems biology approach (Q38106884)

29 August 2017

title

Na/K pump regulation of cardiac repolarization: insights from a systems biology approach (English)

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29 August 2017

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Carlos Sánchez

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Alfonso Bueno-Orovio

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Blanca Rodriguez

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Esther Pueyo

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29 August 2017

publication date

15 May 2013

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29 August 2017

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29 August 2017

volume

466

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29 August 2017

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29 August 2017

page(s)

183-193

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Modulation of cardiac Na+,K+-ATPase cell surface abundance by simulated ischemia-reperfusion and ouabain preconditioning.

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Na/K-ATPase--an integral player in the adrenergic fight-or-flight response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

In vivo human left-to-right ventricular differences in rate adaptation transiently increase pro-arrhythmic risk following rate acceleration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Electrical alternans: membrane-limited and subcellular components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Bridging experiments, models and simulations: an integrative approach to validation in computational cardiac electrophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Mechanisms of ventricular arrhythmias: a dynamical systems-based perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Transport and pharmacological properties of nine different human Na, K-ATPase isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Phospholemman-mediated activation of Na/K-ATPase limits [Na]i and inotropic state during beta-adrenergic stimulation in mouse ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

A model of cardiac electrical activity incorporating ionic pumps and concentration changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Calsequestrin mutation and catecholaminergic polymorphic ventricular tachycardia: a simulation study of cellular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Amiodarone inhibits the 3,5,3'-triiodothyronine-dependent increase of sodium/potassium adenosine triphosphatase activity and concentration in human atrial myocardial tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Cardiac ischemia causes inhibition of the Na/K ATPase by a labile cytosolic compound whose production is linked to oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Regulation of the cardiac sodium pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Steady-state current-voltage relationship of the Na/K pump in guinea pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Ion channels versus ion pumps: the principal difference, in principle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Functional differences between alpha subunit isoforms of the rat Na,K-ATPase expressed in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Contribution of mechanical factors to arrhythmogenesis in calcium overloaded cardiomyocytes: model predictions and experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Systems biology: an approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Simulation analysis of intracellular Na+ and Cl- homeostasis during beta 1-adrenergic stimulation of cardiac myocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

A role for sodium/calcium exchange in the action potential shortening caused by strophanthidin in guinea pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ET(B) receptor-mediated pathway in beating rabbit atria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

A dynamic model of the cardiac ventricular action potential. II. Afterdepolarizations, triggered activity, and potentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Role of individual ionic current systems in ventricular cells hypothesized by a model study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Optimising conditions for studying the acute effects of drugs on indices of cardiac contractility and on haemodynamics in anaesthetized guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Preconditioning by subinotropic doses of ouabain in the Langendorff perfused rabbit heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Crystal structure of the sodium–potassium pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

[Na] and [K] dependence of the Na/K pump current-voltage relationship in guinea pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Repolarization and activation restitution near human pulmonary veins and atrial fibrillation initiation: a mechanism for the initiation of atrial fibrillation by premature beats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

How the Hodgkin-Huxley equations inspired the Cardiac Physiome Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Comparative efficacy of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Simulation study of cellular electric properties in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Characterization of QT interval adaptation to RR interval changes and its use as a risk-stratifier of arrhythmic mortality in amiodarone-treated survivors of acute myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Intracellular [Na(+)] modulates synergy between Na(+)/Ca (2+) exchanger and L-type Ca (2+) current in cardiac excitation-contraction coupling during action potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

NHE inhibition does not improve Na(+) or Ca(2+) overload during reperfusion: using modeling to illuminate the mechanisms underlying a therapeutic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Diverse toxicity associated with cardiac Na+/K+ pump inhibition: evaluation of electrophysiological mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Mechanistic investigation of extracellular K+ accumulation during acute myocardial ischemia: a simulation study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Impact of ionic current variability on human ventricular cellular electrophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Systematic characterization of the ionic basis of rabbit cellular electrophysiology using two ventricular models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Effect of cardiac glycosides on action potential characteristics and contractility in cat ventricular myocytes: role of calcium overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Measurement of Na(+)-K+ pump current in isolated rabbit ventricular myocytes using the whole-cell voltage-clamp technique. Inhibition of the pump by oxidant stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

The influence of some cations on an adenosine triphosphatase from peripheral nerves

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Development of models of active ion transport for whole-cell modelling: cardiac sodium-potassium pump as a case study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

The Na+/K+-ATPase alpha2-isoform regulates cardiac contractility in rat cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Simulation and mechanistic investigation of the arrhythmogenic role of the late sodium current in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

The inhibitory effect of phospholemman on the sodium pump requires its palmitoylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Regional expression of sodium pump subunits isoforms and Na+-Ca++ exchanger in the human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Digitalis: new actions for an old drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

The dynamics of cardiac fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Opposing effects of coupled and uncoupled NOS activity on the Na+-K+ pump in cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Dobutamine-induced spontaneous rhythmic contractions of human isolated atrial strips mimic physiological responses of intact human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-013-1293-1

Active compounds in Chinese herbs and medicinal animal products which promote blood circulation via inhibition of Na+, K+-ATPase.

21 January 2018

1 reference

12 December 2020

Electrophysiology of the sodium-potassium-ATPase in cardiac cells

1 reference

12 December 2020

A COMPARISON OF DIHYDRO-OUABAIN, DIHYDRODIGOXIN, DIHYDRODIGITOXIN, 3-ACETYL STROPHANTHIDIN, ERYSIMIN, AND OUABAIN GIVEN BY CONTINUOUS INFUSION INTO DOGS

1 reference

12 December 2020

Na, K-ATPase: Ubiquitous Multifunctional Transmembrane Protein and its Relevance to Various Pathophysiological Conditions

1 reference

12 December 2020

Measurement and significance of the reversal potential for the pace-maker current (iK2) in sheep Purkinje fibres

1 reference

12 December 2020

Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction

1 reference

12 December 2020

Digitalis for treatment of heart failure in patients in sinus rhythm

1 reference

12 December 2020

Ionic Remodeling Underlying Action Potential Changes in a Canine Model of Atrial Fibrillation

1 reference

12 December 2020

Digoxin-induced delayed afterdepolarizations: biphasic effects of digoxin on action potential duration and the Q-T interval in cardiac Purkinje fibers

1 reference

12 December 2020

Interventricular heterogeneity in rat heart responses to hypoxia: the tuning of glucose metabolism, ion gradients, and function

1 reference

12 December 2020

The cardiac sodium pump: structure and function.

1 reference

12 December 2020

Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes.

1 reference

12 December 2020

KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes

1 reference

12 December 2020

Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure

1 reference

12 December 2020

Dynamics of the QT interval in patients with exercise-induced ventricular tachycardia in normal and abnormal hearts

1 reference

12 December 2020

The balance between inactivation and activation of the Na+-K+ pump underlies the triphasic accumulation of extracellular K+ during myocardial ischemia

1 reference

12 December 2020

The effects of six cardiac glycosides on the transmembrane potential and contractile characteristics of the right ventricle of guinea pigs

1 reference

12 December 2020

Observations on the biphasic nature of digitalis electrophysiological actions in the human right atrium

1 reference

12 December 2020

Combining SERCA2a activation and Na-K ATPase inhibition: a promising new approach to managing acute heart failure syndromes with low cardiac output.

1 reference

12 December 2020

Delayed adaptation of ventricular repolarization after sudden changes in heart rate due to conversion of atrial fibrillation. A potential risk factor for proarrhythmia?

1 reference

12 December 2020

Reciprocal regulation of cardiac Na-K-ATPase and Na/Ca exchanger: hypertension, thyroid hormone, development

1 reference

12 December 2020

Ischemia-induced phosphorylation of phospholemman directly activates rat cardiac Na/K-ATPase

1 reference

12 December 2020

Sodium pump isoform expression in heart failure: implication for treatment.

1 reference

12 December 2020

Action potential duration, rate of stimulation, and intracellular sodium

1 reference

12 December 2020

Relative inotropic and arrhythmogenic effects of five cardiac steroids in ventricular myocardium: oscillatory afterpotentials and the role of endogenous catecholamines.

1 reference

12 December 2020

Characterisation of the Na, K pump current in atrial cells from patients with and without chronic atrial fibrillation

1 reference

12 December 2020

Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failure

1 reference

12 December 2020

10.1007/S00424-013-1293-1

Identifiers

DOI

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Dimensions Publication ID

29 August 2017

1029215898

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