Structure-activity relationships for α-calcitonin gene-related peptide. (Q38062933)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23186257%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

review article

1 reference

title

Structure-activity relationships for α-calcitonin gene-related peptide (English)

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18 February 2020

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18 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23186257%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23186257%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

James Barwell

1 reference

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18 February 2020

Harriet A Watkins

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18 February 2020

language of work or name

English

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publication date

1 December 2013

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British Journal of Pharmacology

18 February 2020

published in

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18 February 2020

volume

170

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18 February 2020

issue

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18 February 2020

page(s)

1308-1322

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Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT((a)) function

18 February 2020

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Dynamic -Helix Structure of Micelle-bound Human Amylin

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Molecular recognition of parathyroid hormone by its G protein-coupled receptor

6 September 2017

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Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

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6 September 2017

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Vascular actions of calcitonin gene-related peptide and adrenomedullin

6 September 2017

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6 September 2017

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International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors

6 September 2017

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Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists

6 September 2017

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Conformation of a peptide ligand bound to its G-protein coupled receptor

6 September 2017

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Effects of glycosylation on the structure and dynamics of eel calcitonin in micelles and lipid bilayers determined by nuclear magnetic resonance spectroscopy

6 September 2017

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6 September 2017

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6 September 2017

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Calcitonin gene-related peptide analogues with aza and indolizidinone amino acid residues reveal conformational requirements for antagonist activity at the human calcitonin gene-related peptide 1 receptor

14 September 2017

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14 September 2017

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28 September 2017

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28 September 2017

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The role of the 8-18 helix of CGRP8-37 in mediating high affinity binding to CGRP receptors; coulombic and steric interactions

23 June 2018

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A comparison of the actions of BIBN4096BS and CGRP(8-37) on CGRP and adrenomedullin receptors expressed on SK-N-MC, L6, Col 29 and Rat 2 cells

23 June 2018

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Bioactive beta-bend structures for the antagonist halpha CGRP(8 - 37) at the CGRP(1) receptor of the rat pulmonary artery

23 June 2018

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On the role of the C-terminus of alpha-calcitonin-gene-related peptide (alpha CGRP). The structure of des-phenylalaninamide37-alpha CGRP and its interaction with the CGRP receptor

23 June 2018

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Structure-activity profile of calcitonin gene-related peptide in peripheral and brain tissues. Evidence for receptor multiplicity

23 June 2018

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hCGRP8-37, a calcitonin gene-related peptide antagonist revealing calcitonin gene-related peptide receptor heterogeneity in brain and periphery

23 June 2018

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Solution structure of human calcitonin gene-related peptide by 1H NMR and distance geometry with restrained molecular dynamics.

23 June 2018

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Structural studies on the [But-Cys18](19-37)-fragment of human β-calcitonin-gene-related peptide

23 June 2018

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Comparative affinities and antagonistic potencies of various human calcitonin gene-related peptide fragments on calcitonin gene-related peptide receptors in brain and periphery

23 June 2018

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Structure-activity study of hCGRP8-37, a calcitonin gene-related peptide receptor antagonist

23 June 2018

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Pharmacological characterization of a receptor for calcitonin gene-related peptide on rat, L6 myocytes

23 June 2018

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Mapping the CGRP receptor ligand binding domain: tryptophan-84 of RAMP1 is critical for agonist and antagonist binding

23 June 2018

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Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23-60 of the calcitonin receptor-like receptor

31 August 2018

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Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor

31 August 2018

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International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor

31 August 2018

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Pharmacology of the human CGRP1 receptor in Cos 7 cells

31 August 2018

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Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity.

31 August 2018

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Turn structures in CGRP C-terminal analogues promote stable arrangements of key residue side chains

31 August 2018

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Structure-activity studies on position 14 of human alpha-calcitonin gene-related peptide.

31 August 2018

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Photoaffinity labeling of rat calcitonin gene-related peptide receptors and adenylate cyclase activation: identification of receptor subtypes

31 August 2018

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Investigation of the structure/activity relationship of human calcitonin gene-related peptide (CGRP).

31 August 2018

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Biological activity of N-terminal fragments of calcitonin gene-related peptide.

31 August 2018

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Identification of the Key Residue of Calcitonin Gene Related Peptide (CGRP) 27−37 to Obtain Antagonists with Picomolar Affinity at the CGRP Receptor

31 August 2018

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Crossref

https://api.crossref.org/works/10.1111%2FBPH.12072

Minimization of parathyroid hormone. Novel amino-terminal parathyroid hormone fragments with enhanced potency in activating the type-1 parathyroid hormone receptor

21 January 2018

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12 December 2020

Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37)

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12 December 2020

Functional characteristics of calcitonin gene-related peptide receptors in human Ewing's sarcoma WE-68 cells

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12 December 2020

CGRP antagonist activity of short C-terminal fragments of human alpha CGRP, CGRP(23-37) and CGRP(19-37)

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12 December 2020

Conformation of human calcitonin gene-related peptide (8-37) in aqueous solution as determined by circular dichroism spectroscopy

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12 December 2020

Constrained analogues of the calcitonin gene-related peptide

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12 December 2020

Structure-activity relationship of adrenomedullin, a novel vasodilatory peptide, in cultured rat vascular smooth muscle cells

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12 December 2020

Structure of human calcitonin gene-related peptide (hCGRP) and of its antagonist hCGRP 8-37 as determined by NMR and molecular modeling

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12 December 2020

Structural comparison of alanine-substituted analogues of the calcitonin gene-related peptide 8-37. Importance of the C-terminal segment for antagonistic activity

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12 December 2020

From Micromolar to Nanomolar Affinity: A Systematic Approach To Identify the Binding Site of CGRP at the Human Calcitonin Gene-Related Peptide 1 Receptor

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12 December 2020

Binding of CGRP analogs and their effect on adenylate cyclase activity in porcine iris-ciliary body

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12 December 2020

CGRP 27-37 analogues with high affinity to the CGRP1 receptor show antagonistic properties in a rat blood flow assay

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12 December 2020

Evolutionary history of the calcitonin gene-related peptide family in vertebrates revealed by comparative genomic analyses

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12 December 2020

Class-B GPCR activation: is ligand helix-capping the key?

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12 December 2020

Novel Peptide Antagonists of Adrenomedullin and Calcitonin Gene-Related Peptide Receptors: Identification, Pharmacological Characterization, and Interactions with Position 74 in Receptor Activity-Modifying Protein 1/3

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12 December 2020

Discovery of potent, cyclic calcitonin gene‐related peptide receptor antagonists

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12 December 2020

Identifiers

DOI

10.1111/BPH.12072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23186257%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23186257%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

23186257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23186257%20AND%20SRC:MED&resulttype=core&format=json