The role of glutamate dehydrogenase in mammalian ammonia metabolism (Q37950871)

25 August 2017

title

The role of glutamate dehydrogenase in mammalian ammonia metabolism (English)

1 reference

25 August 2017

0 references

Cleanthe Spanaki

1 reference

25 August 2017

Andreas Plaitakis

series ordinal

1 reference

25 August 2017

publication date

29 October 2011

1 reference

25 August 2017

published in

Neurotoxicity Research

1 reference

25 August 2017

1 reference

25 August 2017

1 reference

25 August 2017

page(s)

117-127

1 reference

Trade-offs in the adaptation to acidosis

25 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Glial glutamate dehydrogenase: ultrastructural localization and regional distribution in relation to the mitochondrial enzyme, cytochrome oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Estrogen modification of human glutamate dehydrogenases is linked to enzyme activation state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Changes in brain metabolism during hyperammonemia and acute liver failure: results of a comparative 1H-NMR spectroscopy and biochemical investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

The glial cell glutamate uptake carrier countertransports pH-changing anions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Hepatic glutamate metabolism: a tale of 2 hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

A mass isotopomer study of urea and glutamine synthesis from 15N-labeled ammonia in the perfused rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Pathophysiology of hepatic encephalopathy: a new look at ammonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

13N as a tracer for studying glutamate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Cerebral ammonia metabolism in hyperammonemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

The inhibition of glutamate dehydrogenase by some antipsychotic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Detection of structural differences between nuclear and mitochondrial glutamate dehydrogenases by the use of immunoadsorbents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Gender-dependent regulation of glutamate dehydrogenase expression in periportal and pericentral zones of rat liver lobules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Properties and molecular evolution of human GLUD2 (neural and testicular tissue-specific) glutamate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Demonstration of neuron-glia transfer of precursors for GABA biosynthesis in a co-culture system of dissociated mouse cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

The structure and allosteric regulation of glutamate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

The dynamics of ammonia metabolism in man. Effects of liver disease and hyperammonemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Activation of oxoglutarate dehydrogenase in the kidney in response to acute acidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Molecular basis of human glutamate dehydrogenase regulation under changing energy demands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Studies of hepatic glutamine metabolism in the perfused rat liver with (15)N-labeled glutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Fine structural localization of glutamine synthetase in astrocytes of rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Neurological disorders associated with deficiency of glutamate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

The human GLUD2 glutamate dehydrogenase and its regulation in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

The significance of the NH3-NH+(4) equilibrium on the passage of 13N-ammonia from blood to brain. A new regional residue detection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Regulation of renal ammoniagenesis in metabolic acidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Untangling the glutamate dehydrogenase allosteric nightmare

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

On the reversibility of glutamate dehydrogenase and the source of hyperammonemia in the hyperinsulinism/hyperammonemia syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Systemic activation of glutamate dehydrogenase increases renal ammoniagenesis: implications for the hyperinsulinism/hyperammonemia syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

21 January 2018

How to make an ape brain

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9285-4

Factors that affect the uptake of ammonia by the brain: the blood-brain pH gradient

21 January 2018

1 reference

12 December 2020

Subdivision of hexagonal liver lobules into a structural and functional unit; role in hepatic physiology and pathology

1 reference

12 December 2020

Glutamate dehydrogenase activation and ammonia formation by rat kidney mitochondria

1 reference

12 December 2020

Localization of ammonia-metabolizing enzymes in human liver: ontogenesis of heterogeneity

1 reference

12 December 2020

Renal metabolism of amino acids: its role in interorgan amino acid exchange

1 reference

12 December 2020

Mechanisms of glutamate metabolic signaling in retinal glial (Müller) cells

1 reference

12 December 2020

Microquantitative analysis of the intra-acinar profiles of glutamate dehydrogenase in rat liver

1 reference

12 December 2020

Regulation of bovine glutamate dehydrogenase. The effects of pH and ADP

1 reference

12 December 2020

Short-term metabolic fate of [13N]ammonia in rat liver in vivo

1 reference

12 December 2020

Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene

1 reference

12 December 2020

Metabolism of glutamine and glutamate by rat renal tubules. Study with 15N and gas chromatography-mass spectrometry

1 reference

12 December 2020

L-glutamate dehydrogenases: distribution, properties and mechanism.

1 reference

12 December 2020

The influence of diethylstilbestrol and adenosine diphosphate on pyridine nucleotide coenzyme binding by glutamic dehydrogenase

1 reference

12 December 2020

The metabolic fate of 13N-labeled ammonia in rat brain

1 reference

12 December 2020

Effects of chlorpromazine on glutamate dehydrogenase

1 reference

12 December 2020

High protein diet induces pericentral glutamate dehydrogenase and ornithine aminotransferase to provide sufficient glutamate for pericentral detoxification of ammonia in rat liver lobules

1 reference

12 December 2020

Purification and characterization of glutamate dehydrogenase as another isoprotein binding to the membrane of rough endoplasmic reticulum

1 reference

12 December 2020

Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture.

1 reference

12 December 2020

Purification and characterization of a soluble and a particulate glutamate dehydrogenase from rat brain

1 reference

12 December 2020

Quantitative ultrastructural localization of glutamate dehydrogenase in the rat cerebellar cortex

1 reference

12 December 2020

Control of ammoniagenesis by alpha-ketoglutarate in rat kidney mitochondria

1 reference

12 December 2020

Regulation of glutamate dehydrogenase by palmitoyl-coenzyme A

1 reference

12 December 2020

Short-term metabolic fate of 13N-labeled glutamate, alanine, and glutamine(amide) in rat liver

1 reference

12 December 2020

Symposium on acid-base homeostasis. Control of renal production of ammonia

1 reference

12 December 2020

Effect of pH on metabolism of alpha-ketoglutarate by renal cortical mitochondria

1 reference

12 December 2020

Ammonia production in muscle and other tissues: the purine nucleotide cycle

1 reference

12 December 2020

The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants

1 reference

12 December 2020

Severity of hyperammonemic encephalopathy correlates with brain ammonia level and saturation of glutamine synthetase in vivo.

1 reference

12 December 2020

Studies of glutamate dehydrogenase. The interaction of ADP, GTP, and NADPH in complexes with glutamate dehydrogenase

1 reference

12 December 2020

The role of microcompartmentation in the regulation of glutamate metabolism by rat kidney mitochondria

1 reference

12 December 2020

Newer aspects of glutamine/glutamate metabolism: the role of acute pH changes

1 reference

12 December 2020

DISTRIBUTION PATTERN OF SEVERAL ENZYMES IN HUMAN LIVER AND ITS VARIATIONS DURING CELL DAMAGE. III. ON THE METHODOLOGY OF ENZYME DETERMINATION IN HUMAN ORGAN EXTRACTS AND SERUM

1 reference

12 December 2020

10.1007/S12640-011-9285-4

Identifiers

DOI

1 reference

25 August 2017

1 reference