Genetic variability in SNCA and Parkinson's disease (Q37907930)

25 August 2017

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title

Genetic variability in SNCA and Parkinson's disease (English)

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25 August 2017

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Mathias Toft

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25 August 2017

Lasse Pihlstrøm

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25 August 2017

publication date

29 July 2011

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25 August 2017

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25 August 2017

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25 August 2017

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25 August 2017

page(s)

283-293

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Genetic Analysis of Pathways to Parkinson Disease

25 August 2017

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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A large kindred with autosomal dominant Parkinson's disease

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Mapping of a gene for Parkinson's disease to chromosome 4q21-q23

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

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Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications

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alpha-Synuclein locus triplication causes Parkinson's disease

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

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Alpha synuclein promoter and risk of Parkinson's disease: microsatellite and allelic size variability

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Australian data and meta-analysis lend support for alpha-synuclein (NACP-Rep1) as a risk factor for Parkinson's disease

21 January 2018

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Meta-analysis of alpha synuclein/ NACP polymorphism in Parkinson's disease in Japan

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High-resolution whole-genome association study of Parkinson disease.

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Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease

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alpha-Synuclein promoter confers susceptibility to Parkinson's disease.

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Multiple regions of alpha-synuclein are associated with Parkinson's disease

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Alpha-synuclein and familial Parkinson's disease

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SNCA variant associated with Parkinson disease and plasma alpha-synuclein level

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Independent and joint effects of the MAPT and SNCA genes in Parkinson disease

21 January 2018

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

21 January 2018

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Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease

21 January 2018

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Finding the missing heritability of complex diseases

21 January 2018

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Towards a complete resolution of the genetic architecture of disease

21 January 2018

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Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.

21 January 2018

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Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

21 January 2018

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Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

21 January 2018

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Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

21 January 2018

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Genomewide association study for susceptibility genes contributing to familial Parkinson disease

21 January 2018

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Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

21 January 2018

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Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

21 January 2018

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Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population

21 January 2018

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Genome-wide association study confirms extant PD risk loci among the Dutch

21 January 2018

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Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease.

21 January 2018

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21 January 2018

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21 January 2018

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Lack of interaction of SNCA and MAPT genotypes in Parkinson's disease.

21 January 2018

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a-Synuclein gene may interact with environmental factors in increasing risk of Parkinson's disease

21 January 2018

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Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease

21 January 2018

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In vivo demonstration that alpha-synuclein oligomers are toxic

21 January 2018

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Haploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease

21 January 2018

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Allelic imbalance of expression and epigenetic regulation within the alpha-synuclein wild-type and p.Ala53Thr alleles in Parkinson disease.

21 January 2018

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Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

The effect of SNCA 3' region on the levels of SNCA-112 splicing variant

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Genetic variability in the SNCA gene influences α-synuclein levels in the blood and brain

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Genetic association between α-synuclein and idiopathic parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Exploring gene-environment interactions in Parkinson’s disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Distinctive neuropathology revealed by α-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

alpha-synuclein gene haplotypes are associated with Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

21 January 2018

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-Synuclein and Parkinson disease susceptibility

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Multiplealpha-synucleingene polymorphisms are associated with Parkinson’s disease in a Norwegian population

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Alpha-synuclein polymorphisms are associated with Parkinson's disease in a Saskatchewan population

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

Interaction of ?-synuclein and tau genotypes in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

SNCA,MAPT, andGSK3Bin Parkinson disease: a gene-gene interaction study

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10048-011-0292-7

-Synuclein, pesticides, and Parkinson disease: A case-control study

21 January 2018

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Association of alpha-synuclein Rep1 polymorphism and Parkinson's disease: influence of Rep1 on age at onset

21 January 2018

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12 December 2020

Etiology of Parkinson's disease: current concepts

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12 December 2020

Parkinson's disease is not associated with the combined alpha-synuclein/apolipoprotein E susceptibility genotype

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12 December 2020

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

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12 December 2020

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

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12 December 2020

NACP-REP1 polymorphism is not involved in Parkinson's disease: a case-control study in a population sample from southern Italy

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12 December 2020

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12 December 2020

Alpha-synuclein haplotypes implicated in risk of Parkinson's disease

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12 December 2020

Mutation, sequence analysis, and association studies of alpha-synuclein in Parkinson's disease

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12 December 2020

Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein E genotype

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12 December 2020

Characterization of the human alpha-synuclein gene: Genomic structure, transcription start site, promoter region and polymorphisms.

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12 December 2020

Report of familial cases of parkinsonism. Evidence of a dominant trait in a patient's family.

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12 December 2020

Polymorphism of NACP-Rep1 in Parkinson's disease: an etiologic link with essential tremor?

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12 December 2020

The International HapMap Project

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12 December 2020

Reduced expression of the G209A alpha-synuclein allele in familial Parkinsonism.

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12 December 2020

10.1007/S10048-011-0292-7

Identifiers

DOI

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25 August 2017

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