Resveratrol and health--a comprehensive review of human clinical trials (Q37891928)

24 August 2017

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title

Resveratrol and health--a comprehensive review of human clinical trials (English)

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24 August 2017

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24 August 2017

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24 August 2017

Heather A Hausenblas

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24 August 2017

publication date

20 June 2011

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Molecular Nutrition and Food Research

24 August 2017

published in

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24 August 2017

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24 August 2017

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24 August 2017

page(s)

1129-1141

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Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders.

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Effect of exercise training on chronic inflammation

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol, sirtuins, and the promise of a DR mimetic

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Therapeutic potential of resveratrol: the in vivo evidence

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

New enlightenment of French Paradox: resveratrol's potential for cancer chemoprevention and anti-cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Dietary polyphenols: good, bad, or indifferent for your health?

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

SIRT1 transgenic mice show phenotypes resembling calorie restriction

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Crystal structure of quinone reductase 2 in complex with resveratrol

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Usage patterns, health, and nutritional status of long-term multiple dietary supplement users: a cross-sectional study

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Absorption of three wine-related polyphenols in three different matrices by healthy subjects

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Pleiotropic mechanisms facilitated by resveratrol and its metabolites.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Clinical trials of resveratrol

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Bioavailability of trans-resveratrol from red wine in humans.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Polyphenols synergistically inhibit oxidative stress in subjects given red and white wine.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

High absorption but very low bioavailability of oral resveratrol in humans

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Distribution of [3H]trans-resveratrol in rat tissues following oral administration

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Nitrative and oxidative stress in toxicology and disease

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Oxidants, oxidative stress and the biology of ageing

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Oxidants and the pathogenesis of lung diseases

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis--there is nothing more practical than a good theory

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

A Resveratrol and Polyphenol Preparation Suppresses Oxidative and Inflammatory Stress Response to a High-Fat, High-Carbohydrate Meal

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol suppresses body mass gain in a seasonal non-human primate model of obesity

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Biomedical effects of grape products

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Grapes, wines, resveratrol, and heart health

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Grapes and cardiovascular disease

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Cardioprotective actions of grape polyphenols

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Is the association between flow-mediated dilation and cardiovascular risk limited to low-risk populations?

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Challenges of translating basic research into therapeutics: resveratrol as an example

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Chemosensitization of tumors by resveratrol

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol in cancer management: where are we and where we go from here?

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol and cellular mechanisms of cancer prevention

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol preserves cerebrovascular density and cognitive function in aging mice.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Resveratrol induces mitochondrial biogenesis in endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Mitochondrial biogenesis and healthy aging

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Suppression of oxidative stress by resveratrol after isometric contractions in gastrocnemius muscles of aged mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Mediation of endogenous antioxidant enzymes and apoptotic signaling by resveratrol following muscle disuse in the gastrocnemius muscles of young and old rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Red wine triggers cell death and thioredoxin reductase inhibition: effects beyond resveratrol and SIRT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100143

Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201100143

21 January 2018

Identifiers

DOI

10.1002/MNFR.201100143

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24 August 2017

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