SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity (Q33727409)

28 July 2017

title

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity (English)

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28 July 2017

1 reference

Jerrold M Olefsky

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28 July 2017

Takeshi Yoshizaki

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28 July 2017

Simon Schenk

1 reference

28 July 2017

Takeshi Imamura

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28 July 2017

Jennie L Babendure

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28 July 2017

Noriyuki Sonoda

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28 July 2017

Eun Ju Bae

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28 July 2017

Da Young Oh

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28 July 2017

Min Lu

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28 July 2017

Jill C Milne

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28 July 2017

Christoph Westphal

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28 July 2017

Gautam Bandyopadhyay

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28 July 2017

publication date

8 December 2009

1 reference

American Journal of Physiology - Endocrinology and Metabolism

28 July 2017

published in

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28 July 2017

volume

298

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28 July 2017

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28 July 2017

page(s)

E419-28

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describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2838524/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes

21 June 2018

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Palmitate- and lipopolysaccharide-activated macrophages evoke contrasting insulin responses in muscle cells

21 June 2018

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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

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21 June 2018

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

21 June 2018

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JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

21 June 2018

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Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

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21 June 2018

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Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation

21 June 2018

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Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance

21 June 2018

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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

21 June 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 June 2018

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Inflammation and metabolic disorders

21 June 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 June 2018

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Resveratrol improves health and survival of mice on a high-calorie diet

21 June 2018

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Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

21 June 2018

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Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

21 June 2018

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Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice

21 June 2018

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Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance

21 June 2018

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

21 June 2018

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21 June 2018

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A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

21 June 2018

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21 June 2018

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 June 2018

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Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

21 June 2018

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IKK-beta links inflammation to obesity-induced insulin resistance

21 June 2018

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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 June 2018

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21 June 2018

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Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes

21 June 2018

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 June 2018

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Obesity is associated with macrophage accumulation in adipose tissue

21 June 2018

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A central role for JNK in obesity and insulin resistance

21 June 2018

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Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

21 June 2018

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21 June 2018

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Increase in activity during calorie restriction requires Sirt1

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19996381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPENDO.00417.2009

1 reference

28 July 2017

1 reference

28 July 2017

1 reference