STAT3 in tissue fibrosis: Is there a role in the lung? (Q37800646)

23 August 2017

title

STAT3 in tissue fibrosis: is there a role in the lung? (English)

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23 August 2017

STAT3 in tissue fibrosis: Is there a role in the lung? (English)

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Crossref

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

3 August 2024

Darryl Knight

1 reference

23 August 2017

Steven E. Mutsaers

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20951825

3 August 2024

Cecilia M. Prêle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20951825

3 August 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20951825

3 August 2024

publication date

15 October 2010

1 reference

full work available at URL

23 August 2017

https://api.elsevier.com/content/article/PII:S1094553910001197?httpAccept=text/xml

1 reference

Crossref

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

https://api.elsevier.com/content/article/PII:S1094553910001197?httpAccept=text/plain

3 August 2024

1 reference

Crossref

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Pulmonary Pharmacology & Therapeutics

3 August 2024

published in

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23 August 2017

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23 August 2017

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23 August 2017

page(s)

193-198

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Stats: transcriptional control and biological impact

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

The STAT3 isoforms alpha and beta have unique and specific functions

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Of alphas and betas: distinct and overlapping functions of STAT3 isoforms

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Regulation of STAT signalling by proteolytic processing

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Roles of unphosphorylated STATs in signaling

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Acquiring signalling specificity from the cytokine receptor gp130.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Endothelin-1 induces hypertrophy and inhibits apoptosis in human airway smooth muscle cells

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS3 negatively regulates IL-6 signaling in vivo

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

A new protein containing an SH2 domain that inhibits JAK kinases

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Inhibition of Stat1-mediated gene activation by PIAS1

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Specific Inhibition of Stat3 Signal Transduction by PIAS3

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Activation of signal transducer and activator of transcription 3 correlates with cell proliferation and renal injury in human glomerulonephritis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Signal transducer and activator of transcription 3 involvement in the development of renal interstitial fibrosis after unilateral ureteral obstruction

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Idiopathic pulmonary fibrosis: current understanding of the pathogenesis and the status of treatment

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Telomerase mutations in families with idiopathic pulmonary fibrosis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Mechanisms of pulmonary fibrosis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Idiopathic pulmonary fibrosis: current understanding of the pathogenesis and the status of treatment

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

The myofibroblast: one function, multiple origins

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Effect of gamma-interferon on collagen synthesis by normal and fibrotic human lung fibroblasts

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Heterogeneous proliferative characteristics of human adult lung fibroblast lines and clonally derived fibroblasts from control and fibrotic tissue

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Fibroblasts from idiopathic pulmonary fibrosis and normal lungs differ in growth rate, apoptosis, and tissue inhibitor of metalloproteinases expression

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Loss of fibroblast Thy-1 expression correlates with lung fibrogenesis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Enhanced myofibroblastic differentiation and survival in Thy-1(-) lung fibroblasts

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Transforming growth factor-beta stimulates interleukin-11 transcription via complex activating protein-1-dependent pathways

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Stimulatory effect of inflammatory cytokines on alpha 1-antichymotrypsin expression in human lung-derived epithelial cells

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Effect of IL-6 on alveolar fibroblast proliferation in interstitial lung diseases

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNgamma and IL-4 are involved.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS-1 participates in negative regulation of LPS responses

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Suppressor of cytokine signaling 1 inhibits pulmonary inflammation and fibrosis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells.

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Genetics of fibrosing lung diseases

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Determinants of initiation and progression of idiopathic pulmonary fibrosis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymorphisms in patients with idiopathic pulmonary fibrosis

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

A promotor polymorphism in the Interleukin 11 gene is associated with chronic obstructive pulmonary disease

3 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.PUPT.2010.10.005

3 August 2024

Identifiers

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23 August 2017

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