Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6. (Q37740229)

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scientific article published on 16 October 2015

Language	Label	Description	Also known as
English	Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.	scientific article published on 16 October 2015

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6. (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

rheumatoid arthritis

1 reference

based on heuristic

inferred from title

2

0 references

object named as

Anil K Singh

1

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author name string

Sharayah Riegsecker

3

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Europe PubMed Central

PMC publication ID

22 August 2017

Mukesh Chourasia

4

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Salahuddin Ahmed

5

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

publication date

16 October 2015

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Europe PubMed Central

PMC publication ID

22 August 2017

Arthritis & Rheumatology

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Europe PubMed Central

PMC publication ID

22 August 2017

68

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Europe PubMed Central

PMC publication ID

22 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

347-358

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Europe PubMed Central

PMC publication ID

22 August 2017

Treating inflammation by blocking interleukin-1 in humans

1 reference

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22 August 2017

IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production

1 reference

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22 August 2017

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

1 reference

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22 August 2017

Mechanism and in vitro pharmacology of TAK1 inhibition by (5Z)-7-Oxozeaenol

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22 August 2017

β-TrCP-mediated IRAK1 degradation releases TAK1-TRAF6 from the membrane to the cytosol for TAK1-dependent NF-κB activation

1 reference

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22 August 2017

Anakinra as an interleukin 1 receptor antagonist, complicated genetics and molecular impacts--from the point of view of mouse genomics

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Cadherin-11 regulates fibroblast inflammation

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Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

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Breaking the chains: structure and function of the deubiquitinases

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The risk of infections with biologic therapies for rheumatoid arthritis

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22 August 2017

Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.

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22 August 2017

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

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22 August 2017

Risk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trials

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22 August 2017

Ubiquitin-mediated activation of TAK1 and IKK.

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22 August 2017

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

1 reference

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22 August 2017

Ubiquitin signalling in the NF-kappaB pathway

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22 August 2017

Safety of tumour necrosis factor-alpha antagonists

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22 August 2017

TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

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22 August 2017

Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals

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22 August 2017

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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22 August 2017

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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22 August 2017

Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice

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22 August 2017

Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

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22 August 2017

Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB

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22 August 2017

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

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22 August 2017

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

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22 August 2017

Interleukin-1 receptor associated kinase inhibitors: potential therapeutic agents for inflammatory- and immune-related disorders

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22 August 2017

TAK1 selective inhibition: state of the art and future opportunities

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22 August 2017

Small-molecule therapeutics in rheumatoid arthritis: scientific rationale, efficacy and safety

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22 August 2017

Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases

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22 August 2017

Cell type-specific function of TAK1 in innate immune signaling

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22 August 2017

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

1 reference

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22 August 2017

TAK1, more than just innate immunity

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22 August 2017

Targeting of TAK1 in inflammatory disorders and cancer

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22 August 2017

Ubiquitination in signaling to and activation of IKK.

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22 August 2017

In vivo RNAi-mediated silencing of TAK1 decreases inflammatory Th1 and Th17 cells through targeting of myeloid cells.

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14 September 2017

Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner

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Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB.

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28 September 2017

Down-regulation of myeloid cell leukemia 1 by epigallocatechin-3-gallate sensitizes rheumatoid arthritis synovial fibroblasts to tumor necrosis factor alpha-induced apoptosis.

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23 June 2018

Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression.

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Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes

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23 June 2018

Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor

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Multi-omic landscape of rheumatoid arthritis: re-evaluation of drug adverse effects

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Kinase inhibition--a new approach to the treatment of rheumatoid arthritis.

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Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts

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1 September 2018

Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.

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Lack of response to anakinra in rheumatoid arthritis following failure of tumor necrosis factor alpha blockade

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Identifiers

10.1002/ART.39447

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

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