Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation (Q24321363)

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English	Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation	scientific article

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scholarly article

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title

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation (English)

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main subject

cell biology

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TNF receptor associated factor 6

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stated in

GOA release 2020-03-11

response to interleukin-1

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stated in

GOA release 2020-03-11

protein ubiquitination

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based on heuristic

inferred from title

author name string

Betty Lamothe

series ordinal

1

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Arnaud Besse

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2

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Alejandro D Campos

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3

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William K Webster

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4

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Hao Wu

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5

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Bryant G Darnay

series ordinal

6

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language of work or name

English

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publication date

9 February 2007

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published in

Journal of Biological Chemistry

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volume

282

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issue

6

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page(s)

4102-12

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cites work

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TRAF6-deficient mice display hypohidrotic ectodermal dysplasia

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

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Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

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Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster

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TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

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A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

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19 March 2017

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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19 March 2017

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

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19 March 2017

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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19 March 2017

Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif

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Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase

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Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

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7 April 2017

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

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7 April 2017

Ubiquitin signalling in the NF-kappaB pathway

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PubMed Central

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7 April 2017

Ubiquitin: structures, functions, mechanisms

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7 April 2017

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

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Biologic basis for interleukin-1 in disease

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Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli

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Strength of TRAF6 signalling determines osteoclastogenesis

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27 September 2017

RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis.

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Inflammatory diseases: is ubiquitinated NEMO at the hub?

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27 September 2017

The role of TRAF6 in signal transduction and the immune response

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27 September 2017

TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

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27 September 2017

TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor

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27 September 2017

All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction

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27 September 2017

Signal transduction by tumor necrosis factor and its relatives

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27 September 2017

New experimental approaches in retrovirus-mediated expression screening

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27 September 2017

The TRAF6 RING finger domain mediates physical interaction with Ubc13.

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29 November 2018

Identifiers

DOI

10.1074/JBC.M609503200

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4256886

OpenCitations bibliographic resource ID

4256886

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4256886

PMC publication ID

3221607

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4256886

PubMed publication ID

17135271

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4256886

 

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