APC resistance: biological basis and acquired influences (Q37651037)

21 August 2017

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title

APC resistance: biological basis and acquired influences (English)

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21 August 2017

E Castoldi

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21 August 2017

J Rosing

series ordinal

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21 August 2017

publication date

30 November 2009

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Journal of Thrombosis and Haemostasis

21 August 2017

published in

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21 August 2017

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21 August 2017

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21 August 2017

page(s)

445-453

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The anticoagulant protein C pathway

21 August 2017

cites work

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Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C

21 January 2018

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Mutation in blood coagulation factor V associated with resistance to activated protein C.

21 January 2018

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Activated protein C resistance determined with a thrombin generation-based test predicts for venous thrombosis in men and women

21 January 2018

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Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

21 January 2018

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Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va.

21 January 2018

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Peptide Bond Cleavages and Loss of Functional Activity during Inactivation of Factor Va and Factor VaR506Q by Activated Protein C

21 January 2018

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Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

21 January 2018

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Effects of factor Xa and protein S on the individual activated protein C-mediated cleavages of coagulation factor Va.

21 January 2018

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21 January 2018

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Role of P1 residues Arg336 and Arg562 in the activated-Protein-C-catalysed inactivation of Factor VIIIa.

21 January 2018

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Detailed mechanisms of the inactivation of factor VIIIa by activated protein C in the presence of its cofactors, protein S and factor V.

21 January 2018

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Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.

21 January 2018

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21 January 2018

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Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C

21 January 2018

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Determinants of the APTT- and ETP-based APC sensitivity tests.

21 January 2018

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21 January 2018

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Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutations

21 January 2018

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An underestimated combination of opposites resulting in enhanced thrombotic tendency.

21 January 2018

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Intraindividual consistency of the activated protein C resistance phenotype

21 January 2018

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Phenotypic sensitivity to activated protein C in healthy families: importance of genetic components and environmental factors

21 January 2018

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Resistance to activated protein C in healthy women taking oral contraceptives.

21 January 2018

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Genetic determinants of hemostasis phenotypes in Spanish families.

21 January 2018

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A new locus on chromosome 18 that influences normal variation in activated protein C resistance phenotype and factor VIII activity and its relation to thrombosis susceptibility.

21 January 2018

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The activated protein C (APC)-resistant phenotype of APC cleavage site mutants of recombinant factor V in a reconstituted plasma model.

21 January 2018

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Functional characterization of recombinant FV Hong Kong and FV Cambridge.

21 January 2018

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Factor V I359T: a novel mutation associated with thrombosis and resistance to activated protein C.

21 January 2018

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Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency.

21 January 2018

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Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor

21 January 2018

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Regulation of TFPI function by protein S.

21 January 2018

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Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study

21 January 2018

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Mechanisms for acquired activated protein C resistance in cancer patients.

21 January 2018

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Thrombin generation and activated protein C resistance in patients with essential thrombocythemia and polycythemia vera

21 January 2018

1 reference

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Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor VLeiden mutation: a randomized trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2009.03711.X

Effects of the contraceptive patch, the vaginal ring and an oral contraceptive on APC resistance and SHBG: a cross-over study

21 January 2018

1 reference

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Isolation and characterization of an antifactor V antibody causing activated protein C resistance from a patient with severe thrombotic manifestations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2009.03711.X

10.1111/J.1538-7836.2009.03711.X

21 January 2018

Identifiers

DOI

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21 August 2017

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