The chemistry of regulation of genes and other things (Q37608414)

21 August 2017

The chemistry of regulation of genes and other things (English)

1 reference

21 August 2017

Mark Ptashne

1 reference

PMC publication ID

3937619

21 August 2017

language of work or name

English

0 references

publication date

2 January 2014

1 reference

Journal of Biological Chemistry

21 August 2017

1 reference

21 August 2017

289

1 reference

21 August 2017

1 reference

21 August 2017

5417-5435

1 reference

Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Mechanisms and models of somatic cell reprogramming

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Epigenetics: core misconcept

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

A molecular roadmap of reprogramming somatic cells into iPS cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Polycomb-repressed genes have permissive enhancers that initiate reprogramming

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

An effect of DNA sequence on nucleosome occupancy and removal

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Proteolytic instability and the action of nonclassical transcriptional activators

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Forcing cells to change lineages

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Activator control of nucleosome occupancy in activation and repression of transcription

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

On the use of the word 'epigenetic'.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

ISOLATION OF THE lambda PHAGE REPRESSOR

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Isolation of the lac repressor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Targets of the Gal4 transcription activator in functional transcription complexes.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

On the role of Cro in lambda prophage induction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Transcription initiation: imposing specificity by localization

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Octamerization of lambda CI repressor is needed for effective repression of P(RM) and efficient switching from lysogeny

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Activation of gene expression by small molecule transcription factors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Fundamentally different logic of gene regulation in eukaryotes and prokaryotes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Amino acid-amino acid contacts at the cooperativity interface of the bacteriophage lambda and P22 repressors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

The operator-binding domain of lambda repressor: structure and DNA recognition

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Structure of the cro repressor from bacteriophage lambda and its interaction with DNA.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Promoter for the establishment of repressor synthesis in bacteriophage lambda

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Mutant lambda phage repressor with a specific defect in its positive control function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Control of transcription of the repressor gene in bacteriophage lambda

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Regulation of repressor expression in lambda

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Control of lambda repressor synthesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

23 August 2017

The lac operator is DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Sequence of a repressor-binding site in the DNA of bacteriophage lamda

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Multiple Repressor Binding at the Operators in Bacteriophage λ

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Specific DNA binding of GAL4, a positive regulatory protein of yeast

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Recognition of a DNA operator by the repressor of phage 434: a view at high resolution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Cooperative DNA binding of the yeast transcriptional activator GAL4.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

A new class of yeast transcriptional activators

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

GAL4 activates gene expression in mammalian cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

A novel genetic system to detect protein-protein interactions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

The lambda repressor contains two domains

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Mechanism of action of the cro protein of bacteriophage lambda

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Interactions between DNA-bound repressors govern regulation by the λ phage repressor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Evolution of Complex Gene Regulatory Circuits by Addition of Refinements

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Cooperativity in long-range gene regulation by the lambda CI repressor.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

lambda Repressor and cro--components of an efficient molecular switch

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Quantitation of putative activator-target affinities predicts transcriptional activating potentials

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Nucleosomes and the accessibility problem

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Gene regulation at the right operator (OR) of bacteriophage lambda. III. lambda repressor directly activates gene transcription

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Immunity phase-shift in defective lysogens: non-mutational hereditary change of early regulation of lambda prophage.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Cooperative binding of lambda repressors to sites separated by integral turns of the DNA helix

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

DNA loops induced by cooperative binding of lambda repressor

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

GAL4 activates transcription in Drosophila.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Turning lambda Cro into a transcriptional activator

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

How lambda repressor and lambda Cro distinguish between OR1 and OR3.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Generating yeast transcriptional activators containing no yeast protein sequences.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Genetics. Genetics driving epigenetics.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Regulation of a mammalian gene bearing a CpG island promoter and a distal enhancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Francois Jacob (1920-2013).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Binding reactions: epigenetic switches, signal transduction and cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

On speaking, writing and inspiration.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Regulatory functions of the lambda repressor reside in the amino-terminal domain.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Genomic cis-regulatory architecture and trans-acting regulators of a single interneuron-specific gene battery in C. elegans

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Gene regulation at the right operator (OR) of bacteriophage lambda. II. OR1, OR2, and OR3: their roles in mediating the effects of repressor and cro.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

In vitro repression of RNA synthesis by purified lambda phage repressor.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937619

Specific Binding of the λ Phage Repressor to λ DNA

1 September 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X114.547323

Isolation of the 434 Phage Repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X114.547323

Homology among DNA-binding proteins suggests use of a conserved super-secondary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X114.547323

Yeast activators stimulate plant gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X114.547323

Negative effect of the transcriptional activator GAL4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X114.547323

Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X114.547323

Questions over the scientific basis of epigenome project

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X114.547323

Structure of the λ Operators

21 January 2018

1 reference

12 December 2020

Changing the binding specificity of a repressor by redesigning an alpha-helix

1 reference

12 December 2020

Signal transduction. Imposing specificity on kinases

1 reference

12 December 2020

Specificity determinants for the interaction of lambda repressor and P22 repressor dimers

1 reference

12 December 2020

Converting a eukaryotic transcriptional inhibitor into an activator

1 reference

12 December 2020

1 reference

12 December 2020

GAL11P: a yeast mutation that potentiates the effect of weak GAL4-derived activators

1 reference

12 December 2020

Repressor structure and the mechanism of positive control

1 reference

12 December 2020

Single-site mutations in the C-terminal domain of bacteriophage lambda cI repressor alter cooperative interactions between dimers adjacently bound to OR

1 reference

12 December 2020

Autodigestion and RecA-dependent cleavage of Ind- mutant LexA proteins

1 reference

12 December 2020

Gene activation by recruitment of the RNA polymerase II holoenzyme

1 reference

12 December 2020

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1 reference

12 December 2020

Active form of two coliphage repressors

1 reference

12 December 2020

Imposing specificity by localization: mechanism and evolvability

1 reference

12 December 2020

Control of bacteriophage Lambda repressor synthesis: Regulation of the maintenance pathway by the cro and cI products

1 reference

12 December 2020

Imposing specificity by localization: mechanism and evolvability

1 reference

12 December 2020

Faddish stuff: epigenetics and the inheritance of acquired characteristics

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.X114.547323

1 reference

21 August 2017

1 reference

PMC publication ID

3937619

21 August 2017

PubMed publication ID

24385432

1 reference

PMC publication ID

3937619